SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qsv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_B_IBPB1701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	2qsv	UNCHARACTERIZED PROTEIN (Porphyromonas gingivalis)	5 / 11	VAL A 27 ARG A 61 VAL A 39 LEU A 84 LEU A 63	None	1.15A	1eqgB-2qsvA: undetectable	1eqgB-2qsvA: 17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_C_FUAC701_2 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2qsv	UNCHARACTERIZED PROTEIN (Porphyromonas gingivalis)	5 / 12	SER A 6 LEU A 84 VAL A 39 PHE A 53 VAL A 27	None	1.37A	1q23C-2qsvA: undetectable	1q23C-2qsvA: 21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_E_FUAE706_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2qsv	UNCHARACTERIZED PROTEIN (Porphyromonas gingivalis)	5 / 10	SER A 6 LEU A 84 VAL A 39 PHE A 53 VAL A 27	None	1.47A	1q23E-2qsvA: undetectable	1q23E-2qsvA: 21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_J_FUAJ711_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2qsv	UNCHARACTERIZED PROTEIN (Porphyromonas gingivalis)	5 / 11	SER A 6 LEU A 84 VAL A 39 PHE A 53 VAL A 27	None	1.37A	1q23J-2qsvA: undetectable	1q23J-2qsvA: 21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_L_FUAL710_2 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2qsv	UNCHARACTERIZED PROTEIN (Porphyromonas gingivalis)	5 / 11	SER A 6 LEU A 84 VAL A 39 PHE A 53 VAL A 27	None	1.32A	1q23L-2qsvA: undetectable	1q23L-2qsvA: 21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_B_9CRB600_2 (RETINOIC ACID RECEPTOR, BETA)	2qsv	UNCHARACTERIZED PROTEIN (Porphyromonas gingivalis)	3 / 3	LEU A 67 PHE A 12 ARG A 51	None	0.89A	1xdkB-2qsvA: undetectable	1xdkB-2qsvA: 18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA3_A_STRA1001_2 (MINERALOCORTICOID RECEPTOR)	2qsv	UNCHARACTERIZED PROTEIN (Porphyromonas gingivalis)	4 / 4	LEU A 178 LEU A 122 SER A 123 LEU A 126	None	1.13A	1ya3A-2qsvA: undetectable	1ya3A-2qsvA: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KK6_B_CELB1701_2 (PROSTAGLANDIN G/H SYNTHASE 1)	2qsv	UNCHARACTERIZED PROTEIN (Porphyromonas gingivalis)	5 / 6	VAL A 216 SER A 201 ILE A 203 ALA A 164 LEU A 162	None	1.50A	3kk6B-2qsvA: undetectable	3kk6B-2qsvA: 18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TWP_A_SALA404_1 (ANTHRANILATE PHOSPHORIBOSYLTRANSF ERASE)	2qsv	UNCHARACTERIZED PROTEIN (Porphyromonas gingivalis)	4 / 7	ALA A 161 PRO A 160 ARG A 158 ALA A 198	None None None SO4 A 221 ( 3.6A)	1.15A	3twpA-2qsvA: undetectable	3twpA-2qsvA: 24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_I_CLMI221_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2qsv	UNCHARACTERIZED PROTEIN (Porphyromonas gingivalis)	5 / 10	SER A 6 LEU A 84 VAL A 39 PHE A 53 VAL A 27	None	1.49A	3u9fI-2qsvA: undetectable	3u9fI-2qsvA: 21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PH9_A_IBPA601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	2qsv	UNCHARACTERIZED PROTEIN (Porphyromonas gingivalis)	5 / 10	VAL A 27 ARG A 61 VAL A 39 LEU A 84 LEU A 63	None	1.08A	4ph9A-2qsvA: undetectable	4ph9A-2qsvA: 15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PH9_B_IBPB601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	2qsv	UNCHARACTERIZED PROTEIN (Porphyromonas gingivalis)	5 / 10	VAL A 27 ARG A 61 VAL A 39 LEU A 84 LEU A 63	None	1.09A	4ph9B-2qsvA: undetectable	4ph9B-2qsvA: 15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PO0_A_NPSA603_1 (SERUM ALBUMIN)	2qsv	UNCHARACTERIZED PROTEIN (Porphyromonas gingivalis)	5 / 10	LEU A 65 LEU A 82 VAL A 27 LEU A 3 VAL A 86	None	1.07A	4po0A-2qsvA: undetectable	4po0A-2qsvA: 16.47

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EQG_B_IBPB1701_1","PROSTAGLANDIN H2 SYNTHASE-1","2qsv","UNCHARACTERIZED PROTEIN","Porphyromonas gingivalis",5,"VAL A  27;ARG A  61;VAL A  39;LEU A  84;LEU A  63","None","1.15A","1eqgB-2qsvA:undetectable","1eqgB-2qsvA:17.28"],["1Q23_C_FUAC701_2","CHLORAMPHENICOL ACETYLTRANSFERASE","2qsv","UNCHARACTERIZED PROTEIN","Porphyromonas gingivalis",5,"SER A   6;LEU A  84;VAL A  39;PHE A  53;VAL A  27","None","1.37A","1q23C-2qsvA:undetectable","1q23C-2qsvA:21.90"],["1Q23_E_FUAE706_1","CHLORAMPHENICOL ACETYLTRANSFERASE","2qsv","UNCHARACTERIZED PROTEIN","Porphyromonas gingivalis",5,"SER A   6;LEU A  84;VAL A  39;PHE A  53;VAL A  27","None","1.47A","1q23E-2qsvA:undetectable","1q23E-2qsvA:21.90"],["1Q23_J_FUAJ711_1","CHLORAMPHENICOL ACETYLTRANSFERASE","2qsv","UNCHARACTERIZED PROTEIN","Porphyromonas gingivalis",5,"SER A   6;LEU A  84;VAL A  39;PHE A  53;VAL A  27","None","1.37A","1q23J-2qsvA:undetectable","1q23J-2qsvA:21.90"],["1Q23_L_FUAL710_2","CHLORAMPHENICOL ACETYLTRANSFERASE","2qsv","UNCHARACTERIZED PROTEIN","Porphyromonas gingivalis",5,"SER A   6;LEU A  84;VAL A  39;PHE A  53;VAL A  27","None","1.32A","1q23L-2qsvA:undetectable","1q23L-2qsvA:21.90"],["1XDK_B_9CRB600_2","RETINOIC ACID RECEPTOR, BETA","2qsv","UNCHARACTERIZED PROTEIN","Porphyromonas gingivalis",3,"LEU A  67;PHE A  12;ARG A  51","None","0.89A","1xdkB-2qsvA:undetectable","1xdkB-2qsvA:18.97"],["1YA3_A_STRA1001_2","MINERALOCORTICOID RECEPTOR","2qsv","UNCHARACTERIZED PROTEIN","Porphyromonas gingivalis",4,"LEU A 178;LEU A 122;SER A 123;LEU A 126","None","1.13A","1ya3A-2qsvA:undetectable","1ya3A-2qsvA:21.32"],["3KK6_B_CELB1701_2","PROSTAGLANDIN G\/H SYNTHASE 1","2qsv","UNCHARACTERIZED PROTEIN","Porphyromonas gingivalis",5,"VAL A 216;SER A 201;ILE A 203;ALA A 164;LEU A 162","None","1.50A","3kk6B-2qsvA:undetectable","3kk6B-2qsvA:18.20"],["3TWP_A_SALA404_1","ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE","2qsv","UNCHARACTERIZED PROTEIN","Porphyromonas gingivalis",4,"ALA A 161;PRO A 160;ARG A 158;ALA A 198","None;None;None;SO4 A 221 ( 3.6A)","1.15A","3twpA-2qsvA:undetectable","3twpA-2qsvA:24.01"],["3U9F_I_CLMI221_1","CHLORAMPHENICOL ACETYLTRANSFERASE","2qsv","UNCHARACTERIZED PROTEIN","Porphyromonas gingivalis",5,"SER A   6;LEU A  84;VAL A  39;PHE A  53;VAL A  27","None","1.49A","3u9fI-2qsvA:undetectable","3u9fI-2qsvA:21.90"],["4PH9_A_IBPA601_1","PROSTAGLANDIN G\/H SYNTHASE 2","2qsv","UNCHARACTERIZED PROTEIN","Porphyromonas gingivalis",5,"VAL A  27;ARG A  61;VAL A  39;LEU A  84;LEU A  63","None","1.08A","4ph9A-2qsvA:undetectable","4ph9A-2qsvA:15.12"],["4PH9_B_IBPB601_1","PROSTAGLANDIN G\/H SYNTHASE 2","2qsv","UNCHARACTERIZED PROTEIN","Porphyromonas gingivalis",5,"VAL A  27;ARG A  61;VAL A  39;LEU A  84;LEU A  63","None","1.09A","4ph9B-2qsvA:undetectable","4ph9B-2qsvA:15.12"],["4PO0_A_NPSA603_1","SERUM ALBUMIN","2qsv","UNCHARACTERIZED PROTEIN","Porphyromonas gingivalis",5,"LEU A  65;LEU A  82;VAL A  27;LEU A   3;VAL A  86","None","1.07A","4po0A-2qsvA:undetectable","4po0A-2qsvA:16.47"]]