SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qsw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
4 / 6 SER A 313
TYR A 315
VAL A 258
THR A 339
None
1.08A 3tneA-2qswA:
undetectable
3tneA-2qswA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
4 / 7 VAL A 294
ILE A 316
HIS A 287
LEU A 335
None
None
ZN  A 202 ( 3.2A)
None
1.20A 4xo7B-2qswA:
undetectable
4xo7B-2qswA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.57A 5qgjA-2qswA:
undetectable
5qgjA-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.58A 5qglA-2qswA:
undetectable
5qglA-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.61A 5qgmA-2qswA:
undetectable
5qgmA-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.55A 5qgnA-2qswA:
undetectable
5qgnA-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.61A 5qguA-2qswA:
undetectable
5qguA-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.59A 5qgvA-2qswA:
undetectable
5qgvA-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.61A 5qgwA-2qswA:
undetectable
5qgwA-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.59A 5qgxA-2qswA:
undetectable
5qgxA-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.60A 5qgyA-2qswA:
undetectable
5qgyA-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.60A 5qgzA-2qswA:
undetectable
5qgzA-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.61A 5qh0A-2qswA:
undetectable
5qh0A-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.61A 5qh1A-2qswA:
undetectable
5qh1A-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.61A 5qh2A-2qswA:
undetectable
5qh2A-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.60A 5qh3A-2qswA:
undetectable
5qh3A-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.58A 5qh4A-2qswA:
undetectable
5qh4A-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.57A 5qh5A-2qswA:
undetectable
5qh5A-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.59A 5qh6A-2qswA:
undetectable
5qh6A-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.58A 5qh7A-2qswA:
undetectable
5qh7A-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.60A 5qh9A-2qswA:
undetectable
5qh9A-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.63A 5qhaA-2qswA:
undetectable
5qhaA-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.60A 5qhcA-2qswA:
undetectable
5qhcA-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.63A 5qheA-2qswA:
undetectable
5qheA-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.59A 5qhfA-2qswA:
undetectable
5qhfA-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.58A 5qhgA-2qswA:
undetectable
5qhgA-2qswA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
2qsw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2

(Enterococcus
faecalis)
3 / 3 VAL A 341
VAL A 271
GLN A 317
None
0.58A 5qhhA-2qswA:
undetectable
5qhhA-2qswA:
18.23