SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qsx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 2qsx PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
parahaemolyticus) 		5 / 12 PHE A 161
LEU A 211
THR A  23
VAL A  22
LEU A  87
 None
None
SO4  A 216 ( 3.2A)
None
None
 1.08A 1cbsA-2qsxA:
undetectable		 1cbsA-2qsxA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 2qsx PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
parahaemolyticus) 		5 / 12 PHE A 161
LEU A 211
THR A  23
VAL A  22
LEU A  87
 None
None
SO4  A 216 ( 3.2A)
None
None
 1.09A 2fr3A-2qsxA:
undetectable		 2fr3A-2qsxA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 2qsx PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
parahaemolyticus) 		5 / 12 PHE A 161
LEU A 211
THR A  23
VAL A  22
LEU A  87
 None
None
SO4  A 216 ( 3.2A)
None
None
 1.03A 2g78A-2qsxA:
undetectable		 2g78A-2qsxA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 2qsx PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
parahaemolyticus) 		3 / 3 ASP A 171
PHE A 165
SER A  28
 None
 0.96A 3i5uB-2qsxA:
undetectable		 3i5uB-2qsxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2qsx PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
parahaemolyticus) 		4 / 6 ILE A  49
VAL A  47
LEU A  18
LEU A  65
 None
 0.83A 3kp6A-2qsxA:
undetectable
3kp6B-2qsxA:
undetectable		 3kp6A-2qsxA:
18.26
3kp6B-2qsxA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2qsx PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
parahaemolyticus) 		3 / 3 LEU A 158
PRO A 159
ARG A 169
 None
 0.57A 4klrB-2qsxA:
undetectable		 4klrB-2qsxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 2qsx PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
parahaemolyticus) 		5 / 11 LEU A 158
PHE A 142
ALA A 145
THR A 114
ASP A  53
 None
SO4  A 216 ( 4.2A)
None
None
None
 1.33A 4uuuA-2qsxA:
undetectable
4uuuB-2qsxA:
undetectable		 4uuuA-2qsxA:
22.02
4uuuB-2qsxA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 2qsx PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
parahaemolyticus) 		4 / 8 LEU A 211
LEU A  31
THR A  23
GLN A 112
 None
None
SO4  A 216 ( 3.2A)
SO4  A 216 ( 4.4A)
 1.10A 5hbsA-2qsxA:
undetectable		 5hbsA-2qsxA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 2qsx PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
parahaemolyticus) 		4 / 8 LEU A 211
LEU A  31
THR A  23
GLN A 112
 None
None
SO4  A 216 ( 3.2A)
SO4  A 216 ( 4.4A)
 1.03A 5ljbA-2qsxA:
undetectable		 5ljbA-2qsxA:
18.47