SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qt5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_E_TFPE201_1 (PROTEIN S100-A4)	2qt5	GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1 (Rattus norvegicus)	4 / 7	PHE A 162 GLY A 163 PHE A 164 MET A 220	EDO A 1 (-4.9A) None EDO A 1 (-4.3A) EDO A 1 (-3.6A)	0.90A	3ko0D-2qt5A: undetectable 3ko0E-2qt5A: undetectable	3ko0D-2qt5A: 19.00 3ko0E-2qt5A: 19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_M_TFPM201_1 (PROTEIN S100-A4)	2qt5	GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1 (Rattus norvegicus)	4 / 7	MET A 220 PHE A 162 GLY A 163 PHE A 164	EDO A 1 (-3.6A) EDO A 1 (-4.9A) None EDO A 1 (-4.3A)	0.87A	3ko0M-2qt5A: undetectable 3ko0P-2qt5A: undetectable	3ko0M-2qt5A: 19.00 3ko0P-2qt5A: 19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_O_TFPO201_1 (PROTEIN S100-A4)	2qt5	GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1 (Rattus norvegicus)	4 / 8	MET A 220 PHE A 162 GLY A 163 PHE A 164	EDO A 1 (-3.6A) EDO A 1 (-4.9A) None EDO A 1 (-4.3A)	0.97A	3ko0O-2qt5A: undetectable 3ko0Q-2qt5A: undetectable	3ko0O-2qt5A: 19.00 3ko0Q-2qt5A: 19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_Q_TFPQ201_1 (PROTEIN S100-A4)	2qt5	GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1 (Rattus norvegicus)	4 / 8	PHE A 162 GLY A 163 PHE A 164 MET A 220	EDO A 1 (-4.9A) None EDO A 1 (-4.3A) EDO A 1 (-3.6A)	0.95A	3ko0O-2qt5A: undetectable 3ko0Q-2qt5A: undetectable	3ko0O-2qt5A: 19.00 3ko0Q-2qt5A: 19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G1B_D_ECND403_1 (FLAVOHEMOGLOBIN)	2qt5	GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1 (Rattus norvegicus)	5 / 12	ILE A 101 GLN A 94 LEU A 130 VAL A 128 LEU A 66	None	1.09A	4g1bD-2qt5A: undetectable	4g1bD-2qt5A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLR_A_CHDA504_0 (FERROCHELATASE, MITOCHONDRIAL)	2qt5	GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1 (Rattus norvegicus)	4 / 7	LEU A 223 ARG A 167 PRO A 190 VAL A 185	EDO A 1 ( 4.3A) None None None	1.27A	4klrA-2qt5A: undetectable	4klrA-2qt5A: 21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M11_C_MXMC606_2 (PROSTAGLANDIN G/H SYNTHASE 2)	2qt5	GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1 (Rattus norvegicus)	3 / 3	LEU A 203 ARG A 202 MET A 147	None	0.87A	4m11C-2qt5A: undetectable	4m11C-2qt5A: 15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_I_IPHI101_0 (INSULIN)	2qt5	GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1 (Rattus norvegicus)	5 / 12	VAL A 185 LEU A 223 ILE A 182 LEU A 232 LEU A 155	None EDO A 1 ( 4.3A) None None None	1.02A	4p65B-2qt5A: undetectable 4p65D-2qt5A: undetectable 4p65I-2qt5A: undetectable 4p65J-2qt5A: undetectable	4p65B-2qt5A: 9.24 4p65D-2qt5A: 9.24 4p65I-2qt5A: 9.85 4p65J-2qt5A: 9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IM2_A_BEZA401_0 (TWIN-ARGININE TRANSLOCATION PATHWAY SIGNAL)	2qt5	GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1 (Rattus norvegicus)	5 / 12	VAL A 128 ILE A 118 LEU A 120 LEU A 109 VAL A 104	None	1.25A	5im2A-2qt5A: undetectable	5im2A-2qt5A: 17.30

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KO0_E_TFPE201_1","PROTEIN S100-A4;PROTEIN S100-A4","2qt5","GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1","Rattus norvegicus",4,"PHE A 162;GLY A 163;PHE A 164;MET A 220","EDO A   1 (-4.9A);None;EDO A   1 (-4.3A);EDO A   1 (-3.6A)","0.90A","3ko0D-2qt5A:undetectable;3ko0E-2qt5A:undetectable","3ko0D-2qt5A:19.00;3ko0E-2qt5A:19.00"],["3KO0_M_TFPM201_1","PROTEIN S100-A4;PROTEIN S100-A4","2qt5","GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1","Rattus norvegicus",4,"MET A 220;PHE A 162;GLY A 163;PHE A 164","EDO A   1 (-3.6A);EDO A   1 (-4.9A);None;EDO A   1 (-4.3A)","0.87A","3ko0M-2qt5A:undetectable;3ko0P-2qt5A:undetectable","3ko0M-2qt5A:19.00;3ko0P-2qt5A:19.00"],["3KO0_O_TFPO201_1","PROTEIN S100-A4;PROTEIN S100-A4","2qt5","GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1","Rattus norvegicus",4,"MET A 220;PHE A 162;GLY A 163;PHE A 164","EDO A   1 (-3.6A);EDO A   1 (-4.9A);None;EDO A   1 (-4.3A)","0.97A","3ko0O-2qt5A:undetectable;3ko0Q-2qt5A:undetectable","3ko0O-2qt5A:19.00;3ko0Q-2qt5A:19.00"],["3KO0_Q_TFPQ201_1","PROTEIN S100-A4;PROTEIN S100-A4","2qt5","GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1","Rattus norvegicus",4,"PHE A 162;GLY A 163;PHE A 164;MET A 220","EDO A   1 (-4.9A);None;EDO A   1 (-4.3A);EDO A   1 (-3.6A)","0.95A","3ko0O-2qt5A:undetectable;3ko0Q-2qt5A:undetectable","3ko0O-2qt5A:19.00;3ko0Q-2qt5A:19.00"],["4G1B_D_ECND403_1","FLAVOHEMOGLOBIN","2qt5","GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1","Rattus norvegicus",5,"ILE A 101;GLN A  94;LEU A 130;VAL A 128;LEU A  66","None","1.09A","4g1bD-2qt5A:undetectable","4g1bD-2qt5A:20.00"],["4KLR_A_CHDA504_0","FERROCHELATASE, MITOCHONDRIAL","2qt5","GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1","Rattus norvegicus",4,"LEU A 223;ARG A 167;PRO A 190;VAL A 185","EDO A   1 ( 4.3A);None;None;None","1.27A","4klrA-2qt5A:undetectable","4klrA-2qt5A:21.20"],["4M11_C_MXMC606_2","PROSTAGLANDIN G\/H SYNTHASE 2","2qt5","GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1","Rattus norvegicus",3,"LEU A 203;ARG A 202;MET A 147","None","0.87A","4m11C-2qt5A:undetectable","4m11C-2qt5A:15.63"],["4P65_I_IPHI101_0","INSULIN","2qt5","GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1","Rattus norvegicus",5,"VAL A 185;LEU A 223;ILE A 182;LEU A 232;LEU A 155","None;EDO A   1 ( 4.3A);None;None;None","1.02A","4p65B-2qt5A:undetectable;4p65D-2qt5A:undetectable;4p65I-2qt5A:undetectable;4p65J-2qt5A:undetectable","4p65B-2qt5A:9.24;4p65D-2qt5A:9.24;4p65I-2qt5A:9.85;4p65J-2qt5A:9.24"],["5IM2_A_BEZA401_0","TWIN-ARGININE TRANSLOCATION PATHWAY SIGNAL","2qt5","GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1","Rattus norvegicus",5,"VAL A 128;ILE A 118;LEU A 120;LEU A 109;VAL A 104","None","1.25A","5im2A-2qt5A:undetectable","5im2A-2qt5A:17.30"]]