SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qu7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		3 / 3 ASP A 147
ARG A 148
ILE A 190
 None
 0.82A 1a4gB-2qu7A:
undetectable		 1a4gB-2qu7A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		5 / 11 LEU A 259
GLY A 277
ALA A 249
GLY A 246
ILE A 274
 None
 0.97A 1hxwB-2qu7A:
undetectable		 1hxwB-2qu7A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		4 / 8 PHE A  77
PHE A  69
ALA A 305
LEU A 323
 None
 1.17A 1x8vA-2qu7A:
undetectable		 1x8vA-2qu7A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		5 / 9 LEU A 183
THR A 250
ALA A 249
LEU A 239
LEU A 255
 None
 1.25A 2npnA-2qu7A:
3.9		 2npnA-2qu7A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		5 / 12 GLY A 277
ALA A 249
VAL A 181
GLY A 246
ILE A 274
 None
 0.87A 3ekwB-2qu7A:
undetectable		 3ekwB-2qu7A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		5 / 9 LEU A 259
GLY A 277
ALA A 249
GLY A 246
ILE A 274
 None
 1.05A 3gguB-2qu7A:
undetectable		 3gguB-2qu7A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		4 / 4 LEU A 111
MET A 134
ILE A  85
ASP A 147
 None
 0.97A 3hecA-2qu7A:
undetectable		 3hecA-2qu7A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		4 / 4 GLN A 296
PRO A 297
VAL A 298
GLU A  84
 None
 1.48A 3huoA-2qu7A:
undetectable		 3huoA-2qu7A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		4 / 8 ILE A 216
ALA A 166
THR A 170
VAL A 211
 None
 0.91A 3me6B-2qu7A:
undetectable		 3me6B-2qu7A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		5 / 11 VAL A 273
ILE A 247
GLY A 277
VAL A 293
ILE A 269
 None
 1.04A 3oxvD-2qu7A:
undetectable		 3oxvD-2qu7A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		5 / 8 GLY A 277
ALA A 249
GLY A 246
ILE A 274
THR A 236
 None
 1.40A 3so9A-2qu7A:
undetectable		 3so9A-2qu7A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		4 / 5 GLU A 149
ASP A 161
ASN A 198
GLU A 163
 None
 1.33A 3vywD-2qu7A:
undetectable		 3vywD-2qu7A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		3 / 3 ASN A  75
ASP A 279
ASN A 251
 None
 0.70A 4agaA-2qu7A:
undetectable		 4agaA-2qu7A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		4 / 8 GLY A 232
ALA A 261
LYS A 237
GLU A 264
 None
 0.88A 4bjcA-2qu7A:
undetectable		 4bjcA-2qu7A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		5 / 9 LEU A 259
GLY A 277
ALA A 249
GLY A 246
ILE A 274
 None
 1.06A 4dqcB-2qu7A:
undetectable		 4dqcB-2qu7A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		3 / 3 GLU A 163
LYS A 202
ASN A 198
 None
 0.85A 4y1dA-2qu7A:
undetectable
4y1dD-2qu7A:
undetectable		 4y1dA-2qu7A:
21.09
4y1dD-2qu7A:
3.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		5 / 12 HIS A 252
VAL A 293
LEU A 146
PHE A  69
THR A  79
 None
 1.46A 6brdA-2qu7A:
2.9		 6brdA-2qu7A:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Staphylococcus
saprophyticus) 		5 / 11 VAL A 304
VAL A 160
LEU A 323
GLN A 296
VAL A  81
 None
 1.10A 6dryA-2qu7A:
undetectable		 6dryA-2qu7A:
22.27