SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qul'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		4 / 4 VAL A 128
ALA A 131
LEU A 151
PHE A 110
 None
 1.08A 1q97B-2qulA:
undetectable		 1q97B-2qulA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		3 / 3 VAL A 154
ASP A 185
GLU A 158
 None
MN  A 291 (-3.1A)
None
 0.69A 2qeuA-2qulA:
1.1		 2qeuA-2qulA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		3 / 3 VAL A 154
ASP A 185
GLU A 158
 None
MN  A 291 (-3.1A)
None
 0.68A 2qeuC-2qulA:
undetectable		 2qeuC-2qulA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		5 / 12 PHE A 248
THR A  22
PHE A  19
LEU A  38
GLU A  35
 None
 1.33A 3apxA-2qulA:
undetectable		 3apxA-2qulA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		5 / 9 LEU A  33
VAL A 244
LEU A 100
ILE A  36
ALA A 102
 None
 1.04A 3mdvA-2qulA:
undetectable		 3mdvA-2qulA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		6 / 12 LEU A  33
VAL A 244
LEU A 100
ILE A  36
ALA A 106
ALA A 102
 None
 1.20A 3mdvB-2qulA:
undetectable		 3mdvB-2qulA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		4 / 8 ASP A 185
PHE A 248
VAL A 259
HIS A 188
 MN  A 291 (-3.1A)
None
None
None
 1.21A 4f5zA-2qulA:
undetectable		 4f5zA-2qulA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		5 / 12 HIS A 188
VAL A 259
GLU A  35
HIS A 209
GLY A   5
 None
 1.40A 4hvcA-2qulA:
undetectable		 4hvcA-2qulA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		5 / 12 VAL A 255
PHE A   7
PHE A 248
GLY A 260
THR A   9
 None
 1.17A 4mm4A-2qulA:
undetectable		 4mm4A-2qulA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		5 / 12 VAL A 255
PHE A   7
PHE A 248
GLY A 260
THR A   9
 None
 1.16A 4mm4B-2qulA:
undetectable		 4mm4B-2qulA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		5 / 12 LEU A  94
ALA A  85
PHE A  75
LEU A 108
VAL A 135
 None
 1.29A 4nc3A-2qulA:
undetectable		 4nc3A-2qulA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		5 / 12 ARG A 217
VAL A 244
ILE A 243
LEU A 225
ILE A 230
 MN  A 291 ( 4.8A)
None
None
None
None
 1.09A 5b8iC-2qulA:
undetectable		 5b8iC-2qulA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		3 / 3 ASN A 190
ALA A 215
ARG A 224
 None
 0.68A 5cvtB-2qulA:
undetectable		 5cvtB-2qulA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		5 / 12 GLY A 253
VAL A 261
TRP A 113
SER A  37
GLY A  68
 None
 1.27A 5f9zA-2qulA:
undetectable		 5f9zA-2qulA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		5 / 9 VAL A 175
ALA A 131
PHE A  75
VAL A 138
ILE A 139
 None
 1.07A 5om2A-2qulA:
undetectable
5om2B-2qulA:
undetectable		 5om2A-2qulA:
14.83
5om2B-2qulA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		4 / 6 ARG A 217
HIS A 188
LEU A 108
PRO A 114
 MN  A 291 ( 4.8A)
None
None
None
 1.46A 5syjA-2qulA:
undetectable		 5syjA-2qulA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		4 / 5 GLY A 241
THR A 242
ASN A   2
LYS A   3
 None
 1.08A 5x23A-2qulA:
undetectable		 5x23A-2qulA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		4 / 6 GLY A 241
THR A 242
ASN A   2
LYS A   3
 None
 0.89A 5xxiA-2qulA:
undetectable		 5xxiA-2qulA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 2qul D-TAGATOSE
3-EPIMERASE
(Pseudomonas
cichorii) 		4 / 8 HIS A  42
GLY A  39
LEU A  69
GLY A  68
 None
 0.84A 6mdqA-2qulA:
undetectable		 6mdqA-2qulA:
15.60