SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qup'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 2qup BH1478 PROTEIN
(Bacillus
halodurans) 		4 / 7 SER A  48
ASP A  52
LEU A  72
GLU A  75
 None
 1.10A 2cdqB-2qupA:
undetectable		 2cdqB-2qupA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 2qup BH1478 PROTEIN
(Bacillus
halodurans) 		5 / 12 ILE A 141
GLY A  78
VAL A 108
ILE A 104
VAL A 105
 None
 0.97A 4c9lA-2qupA:
undetectable		 4c9lA-2qupA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 2qup BH1478 PROTEIN
(Bacillus
halodurans) 		5 / 12 ILE A 141
GLY A  78
VAL A 108
ILE A 104
VAL A 105
 None
 0.99A 4c9lB-2qupA:
undetectable		 4c9lB-2qupA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 2qup BH1478 PROTEIN
(Bacillus
halodurans) 		5 / 12 ILE A 141
GLY A  78
VAL A 108
ILE A 104
VAL A 105
 None
 0.95A 4c9oA-2qupA:
undetectable		 4c9oA-2qupA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 2qup BH1478 PROTEIN
(Bacillus
halodurans) 		5 / 12 ILE A 141
GLY A  78
VAL A 108
ILE A 104
VAL A 105
 None
 0.96A 4c9oB-2qupA:
undetectable		 4c9oB-2qupA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2qup BH1478 PROTEIN
(Bacillus
halodurans) 		4 / 6 GLU A  89
ARG A  90
ASP A  36
ARG A  35
 None
 1.29A 4kcnA-2qupA:
2.3		 4kcnA-2qupA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2qup BH1478 PROTEIN
(Bacillus
halodurans) 		4 / 6 GLU A  89
ARG A  90
ASP A  36
ARG A  35
 None
 1.28A 4kcnB-2qupA:
2.3		 4kcnB-2qupA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 2qup BH1478 PROTEIN
(Bacillus
halodurans) 		4 / 5 LEU A  43
ALA A 145
VAL A 105
ILE A 104
 None
 0.86A 4xe3B-2qupA:
undetectable		 4xe3B-2qupA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2qup BH1478 PROTEIN
(Bacillus
halodurans) 		4 / 7 GLY A  78
VAL A 108
ILE A 104
VAL A 105
 None
 0.79A 5ik1A-2qupA:
2.0		 5ik1A-2qupA:
17.00