SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qv0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 2qv0 PROTEIN MRKE
(Klebsiella
pneumoniae) 		5 / 12 LEU A 121
ILE A  77
SER A  74
VAL A  95
ILE A 113
 None
 0.82A 3frqB-2qv0A:
undetectable		 3frqB-2qv0A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 2qv0 PROTEIN MRKE
(Klebsiella
pneumoniae) 		5 / 9 ILE A 125
LEU A  99
ILE A 113
PHE A  89
GLY A  87
 None
 0.96A 3sj4X-2qv0A:
undetectable		 3sj4X-2qv0A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2qv0 PROTEIN MRKE
(Klebsiella
pneumoniae) 		4 / 8 LEU A 150
ILE A 107
VAL A  95
GLY A 118
 None
 0.85A 4eq4B-2qv0A:
2.7		 4eq4B-2qv0A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 2qv0 PROTEIN MRKE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 118
ILE A 125
GLU A  64
VAL A  63
ILE A  61
 None
 1.02A 6ecxA-2qv0A:
2.4		 6ecxA-2qv0A:
20.62