SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qv5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		5 / 11 PHE A 303
ILE A 296
LEU A 229
MET A 265
ALA A 266
 None
 1.34A 1ju6A-2qv5A:
undetectable		 1ju6A-2qv5A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		5 / 11 PHE A 303
ILE A 296
LEU A 229
MET A 265
ALA A 266
 None
 1.33A 1ju6D-2qv5A:
undetectable		 1ju6D-2qv5A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		5 / 12 ILE A 359
GLY A 360
VAL A 389
VAL A 361
ALA A 362
 None
 1.06A 1vptA-2qv5A:
undetectable		 1vptA-2qv5A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		4 / 4 ILE A 258
ASP A 246
LEU A 233
ARG A 299
 None
 0.98A 2a7qA-2qv5A:
undetectable		 2a7qA-2qv5A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		3 / 3 PRO A 243
THR A 241
PRO A 239
 None
 0.72A 2d55C-2qv5A:
undetectable		 2d55C-2qv5A:
6.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		5 / 12 GLY A 210
GLY A 205
ARG A 215
ALA A 220
ASP A 219
 None
 1.11A 3keeD-2qv5A:
undetectable		 3keeD-2qv5A:
26.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		5 / 11 GLY A 388
THR A 272
GLU A 226
LEU A 228
LEU A 302
 None
 1.37A 3ndvA-2qv5A:
undetectable
3ndvB-2qv5A:
undetectable		 3ndvA-2qv5A:
24.40
3ndvB-2qv5A:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		5 / 11 LEU A 302
GLY A 388
THR A 272
GLU A 226
LEU A 228
 None
 1.38A 3ndvC-2qv5A:
undetectable
3ndvD-2qv5A:
undetectable		 3ndvC-2qv5A:
24.40
3ndvD-2qv5A:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		5 / 12 SER A 376
LEU A 204
ILE A 372
ALA A 362
ALA A 358
 None
 1.15A 3nxuB-2qv5A:
undetectable		 3nxuB-2qv5A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		3 / 3 MET A 217
MET A 275
TYR A 165
 None
 1.12A 4p6xI-2qv5A:
undetectable		 4p6xI-2qv5A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		4 / 8 LEU A 301
PRO A 324
VAL A 393
SER A 390
 None
 1.01A 4qknA-2qv5A:
undetectable		 4qknA-2qv5A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		5 / 10 GLY A 315
GLN A 325
LEU A 304
ALA A 328
ASP A 329
 None
 1.29A 4wnuD-2qv5A:
undetectable		 4wnuD-2qv5A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		5 / 12 PHE A 303
ILE A 258
LEU A 289
LEU A 233
LEU A 248
 None
 1.31A 4xumA-2qv5A:
undetectable		 4xumA-2qv5A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		5 / 12 PHE A 303
ILE A 296
LEU A 229
MET A 265
ALA A 266
 None
 1.38A 5fctB-2qv5A:
undetectable		 5fctB-2qv5A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		5 / 12 ILE A 268
LEU A 229
GLY A 244
PRO A 243
LEU A 148
 None
 1.15A 5ienA-2qv5A:
undetectable		 5ienA-2qv5A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		3 / 3 SER A 312
SER A 309
PHE A 303
 None
 0.76A 5mugA-2qv5A:
1.7		 5mugA-2qv5A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 2qv5 UNCHARACTERIZED
PROTEIN ATU2773
(Agrobacterium
fabrum) 		3 / 3 TRP A 375
ILE A 384
GLU A 201
 None
 0.80A 6hcxA-2qv5A:
undetectable		 6hcxA-2qv5A:
14.00