SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qv8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2qv8 GENERAL SECRETION
PATHWAY PROTEIN H
(Vibrio
cholerae) 		5 / 11 THR A  91
PHE A 101
PHE A  39
LEU A  46
VAL A 143
 None
 1.40A 1q23G-2qv8A:
undetectable		 1q23G-2qv8A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2qv8 GENERAL SECRETION
PATHWAY PROTEIN H
(Vibrio
cholerae) 		4 / 8 LEU A 177
GLN A 172
LEU A  43
PHE A  39
 None
 0.91A 1v54C-2qv8A:
undetectable
1v54J-2qv8A:
undetectable		 1v54C-2qv8A:
17.74
1v54J-2qv8A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qv8 GENERAL SECRETION
PATHWAY PROTEIN H
(Vibrio
cholerae) 		4 / 8 LEU A 177
GLN A 172
LEU A  43
PHE A  39
 None
 0.89A 2dyrC-2qv8A:
undetectable
2dyrJ-2qv8A:
undetectable		 2dyrC-2qv8A:
17.74
2dyrJ-2qv8A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qv8 GENERAL SECRETION
PATHWAY PROTEIN H
(Vibrio
cholerae) 		4 / 7 LEU A 177
GLN A 172
LEU A  43
PHE A  39
 None
 1.03A 2dysC-2qv8A:
undetectable
2dysJ-2qv8A:
undetectable		 2dysC-2qv8A:
17.74
2dysJ-2qv8A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qv8 GENERAL SECRETION
PATHWAY PROTEIN H
(Vibrio
cholerae) 		4 / 7 LEU A 177
GLN A 172
LEU A  43
PHE A  39
 None
 0.91A 2zxwC-2qv8A:
undetectable
2zxwJ-2qv8A:
undetectable		 2zxwC-2qv8A:
17.74
2zxwJ-2qv8A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qv8 GENERAL SECRETION
PATHWAY PROTEIN H
(Vibrio
cholerae) 		4 / 6 LEU A 177
GLN A 172
LEU A  43
PHE A  39
 None
 0.96A 2zxwP-2qv8A:
undetectable
2zxwW-2qv8A:
undetectable		 2zxwP-2qv8A:
17.74
2zxwW-2qv8A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qv8 GENERAL SECRETION
PATHWAY PROTEIN H
(Vibrio
cholerae) 		4 / 6 LEU A 177
GLN A 172
LEU A  43
PHE A  39
 None
 0.95A 3ag1C-2qv8A:
undetectable
3ag1J-2qv8A:
undetectable		 3ag1C-2qv8A:
17.74
3ag1J-2qv8A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2qv8 GENERAL SECRETION
PATHWAY PROTEIN H
(Vibrio
cholerae) 		4 / 8 LEU A 177
GLN A 172
LEU A  43
PHE A  39
 None
 0.94A 3asoC-2qv8A:
undetectable
3asoJ-2qv8A:
undetectable		 3asoC-2qv8A:
17.74
3asoJ-2qv8A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 2qv8 GENERAL SECRETION
PATHWAY PROTEIN H
(Vibrio
cholerae) 		4 / 8 GLU A  49
GLN A  55
GLY A  54
SER A  53
 None
 0.82A 4f93B-2qv8A:
undetectable		 4f93B-2qv8A:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 2qv8 GENERAL SECRETION
PATHWAY PROTEIN H
(Vibrio
cholerae) 		3 / 3 ARG A  60
LYS A  81
GLU A 136
 None
 0.80A 5d0yA-2qv8A:
undetectable		 5d0yA-2qv8A:
20.40