SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qve'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 8 SER A 337
GLY A 358
THR A 207
ILE A 361
 None
 0.68A 1c9sI-2qveA:
undetectable
1c9sJ-2qveA:
undetectable		 1c9sI-2qveA:
11.96
1c9sJ-2qveA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 8 GLY A 358
THR A 207
ILE A 361
SER A 337
 None
 0.69A 1c9sU-2qveA:
undetectable
1c9sV-2qveA:
undetectable		 1c9sU-2qveA:
11.96
1c9sV-2qveA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_B_SAMB105_0
(MET REPRESSOR)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 10 GLU A 199
ARG A 196
GLU A  53
ALA A 123
GLY A 120
 None
 1.24A 1cmcA-2qveA:
undetectable
1cmcB-2qveA:
undetectable		 1cmcA-2qveA:
11.20
1cmcB-2qveA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 LEU A  20
LEU A 335
SER A 208
VAL A  15
LEU A 129
 None
 1.34A 1db1A-2qveA:
undetectable		 1db1A-2qveA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		3 / 3 MET A 447
LEU A 150
SER A 149
 None
None
MDO  A 152 ( 4.0A)
 0.66A 1ee2A-2qveA:
undetectable		 1ee2A-2qveA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 7 GLY A 358
THR A 207
ILE A 361
SER A 337
 None
 0.64A 1gtnA-2qveA:
undetectable
1gtnK-2qveA:
undetectable		 1gtnA-2qveA:
11.96
1gtnK-2qveA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 8 SER A 337
GLY A 358
THR A 207
ILE A 361
 None
 0.66A 1gtnA-2qveA:
undetectable
1gtnB-2qveA:
undetectable		 1gtnA-2qveA:
11.96
1gtnB-2qveA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 7 SER A 337
GLY A 358
THR A 207
ILE A 361
 None
 0.72A 1gtnC-2qveA:
undetectable
1gtnD-2qveA:
undetectable		 1gtnC-2qveA:
11.96
1gtnD-2qveA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 6 SER A 337
GLY A 358
THR A 207
ILE A 361
 None
 0.65A 1gtnD-2qveA:
undetectable
1gtnE-2qveA:
undetectable		 1gtnD-2qveA:
11.96
1gtnE-2qveA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 8 SER A 337
GLY A 358
THR A 207
ILE A 361
 None
 0.69A 1gtnE-2qveA:
undetectable
1gtnF-2qveA:
undetectable		 1gtnE-2qveA:
11.96
1gtnF-2qveA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 7 SER A 337
GLY A 358
THR A 207
ILE A 361
 None
 0.70A 1gtnF-2qveA:
undetectable
1gtnG-2qveA:
undetectable		 1gtnF-2qveA:
11.96
1gtnG-2qveA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 8 SER A 337
GLY A 358
THR A 207
ILE A 361
 None
 0.68A 1gtnI-2qveA:
undetectable
1gtnJ-2qveA:
undetectable		 1gtnI-2qveA:
11.96
1gtnJ-2qveA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 7 SER A 337
GLY A 358
THR A 207
ILE A 361
 None
 0.62A 1gtnJ-2qveA:
undetectable
1gtnK-2qveA:
undetectable		 1gtnJ-2qveA:
11.96
1gtnK-2qveA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 8 GLY A 358
THR A 207
ILE A 361
SER A 337
 None
 0.64A 1gtnP-2qveA:
undetectable
1gtnQ-2qveA:
undetectable		 1gtnP-2qveA:
11.96
1gtnQ-2qveA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_A_ACTA703_0
(FUMARATE REDUCTASE
FLAVOPROTEIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 4 PHE A 483
ASP A 478
ARG A 498
GLU A 495
 None
 1.11A 1kf6A-2qveA:
5.2		 1kf6A-2qveA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 5 ARG A 508
LEU A 516
ASP A 513
LEU A 471
 None
 1.18A 1n13B-2qveA:
undetectable
1n13C-2qveA:
undetectable		 1n13B-2qveA:
11.17
1n13C-2qveA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 ILE A 465
LEU A 378
ALA A 379
LEU A 521
LEU A 459
 None
 1.21A 1og5B-2qveA:
undetectable		 1og5B-2qveA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 LEU A 372
LEU A 375
LEU A 378
GLN A 382
LEU A 521
 None
 0.87A 1sqnB-2qveA:
undetectable		 1sqnB-2qveA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 8 GLY A 358
THR A 207
ILE A 361
SER A 337
 None
 0.72A 1utdB-2qveA:
undetectable
1utdC-2qveA:
undetectable		 1utdB-2qveA:
11.96
1utdC-2qveA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 8 GLY A 358
THR A 207
ILE A 361
SER A 337
 None
 0.70A 1utdF-2qveA:
undetectable
1utdG-2qveA:
undetectable		 1utdF-2qveA:
11.96
1utdG-2qveA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 8 GLY A 358
THR A 207
ILE A 361
SER A 337
 None
 0.68A 1utdI-2qveA:
undetectable
1utdJ-2qveA:
undetectable		 1utdI-2qveA:
11.96
1utdJ-2qveA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 8 GLY A 358
THR A 207
ILE A 361
SER A 337
 None
 0.70A 1utdJ-2qveA:
undetectable
1utdK-2qveA:
undetectable		 1utdJ-2qveA:
11.96
1utdK-2qveA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 6 ALA A 228
GLU A 229
ILE A 313
LEU A 375
 None
 0.84A 1xvaA-2qveA:
undetectable
1xvaB-2qveA:
undetectable		 1xvaA-2qveA:
20.11
1xvaB-2qveA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 LEU A 372
LEU A 375
LEU A 378
ALA A 379
GLN A 382
 None
 0.66A 1ya3C-2qveA:
undetectable		 1ya3C-2qveA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 LEU A 372
LEU A 375
LEU A 378
GLN A 382
LEU A 521
 None
 0.79A 1ya3C-2qveA:
undetectable		 1ya3C-2qveA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AXN_A_EDTA737_0
(6-PHOSPHOFRUCTO-2-KI
NASE/FRUCTOSE-2,6-BI
PHOSPHATASE 3
(6PF-2-K/FRU-
2,6-P2ASE
BRAIN/PLACENTA-TYPE
ISOZYME) (IPFK-2)
[INCLUDES: 6-
PHOSPHOFRUCTO-2-KINA
SE (EC 2.7.1.105)
FRUCTOSE-2,6-BISPHO
SPHATASE (EC
3.1.3.46)])		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 GLY A 376
ARG A 381
ALA A 417
THR A 418
ARG A 425
 None
 1.44A 2axnA-2qveA:
undetectable		 2axnA-2qveA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 LEU A 213
ALA A 108
ARG A 220
SER A 208
ALA A 452
 None
 1.25A 2ejtA-2qveA:
undetectable		 2ejtA-2qveA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 ALA A 452
ASP A 104
GLY A 219
LEU A 222
LEU A 213
 None
 1.35A 2nv4B-2qveA:
undetectable		 2nv4B-2qveA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 5 ALA A 379
ALA A 472
ALA A 476
VAL A 239
 None
 0.92A 2nyrB-2qveA:
undetectable		 2nyrB-2qveA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 LEU A 372
LEU A 378
ALA A 379
GLN A 382
LEU A 521
 None
 1.03A 2oaxB-2qveA:
undetectable		 2oaxB-2qveA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 LEU A 372
LEU A 378
ALA A 379
GLN A 382
LEU A 521
 None
 1.10A 2oaxD-2qveA:
undetectable		 2oaxD-2qveA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 LEU A 372
LEU A 378
ALA A 379
GLN A 382
LEU A 521
 None
 1.06A 2oaxE-2qveA:
undetectable		 2oaxE-2qveA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 THR A 493
LEU A 235
VAL A 477
THR A 243
ILE A 313
 None
 1.22A 2vn0A-2qveA:
undetectable		 2vn0A-2qveA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 7 ILE A 144
LEU A 100
GLY A  98
GLY A  96
 None
 0.77A 2wd9A-2qveA:
undetectable		 2wd9A-2qveA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 8 LEU A 459
ARG A 220
GLY A 219
ALA A 221
 None
 0.85A 2xfsA-2qveA:
undetectable		 2xfsA-2qveA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 8 LEU A 459
ARG A 220
GLY A 219
ALA A 221
 None
 0.83A 2xh9A-2qveA:
undetectable		 2xh9A-2qveA:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 6 LEU A 166
ILE A 128
ILE A  62
LEU A  85
 None
 0.85A 2xkwB-2qveA:
undetectable		 2xkwB-2qveA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		3 / 3 GLY A 485
GLY A 273
GLY A 275
 None
 0.41A 3bogC-2qveA:
undetectable		 3bogC-2qveA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 4 THR A 141
VAL A  28
GLY A 212
THR A 211
 None
 0.91A 3cflA-2qveA:
undetectable		 3cflA-2qveA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_0
(NEURAMINIDASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 GLU A  30
LEU A 216
ARG A  27
GLU A  31
ARG A 528
 None
 1.20A 3k37B-2qveA:
undetectable		 3k37B-2qveA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 GLU A  30
LEU A 216
ARG A  27
GLU A  31
ARG A 528
 None
 1.23A 3k39D-2qveA:
undetectable		 3k39D-2qveA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 GLU A  30
LEU A 216
ARG A  27
GLU A  31
ARG A 528
 None
 1.23A 3k39N-2qveA:
undetectable		 3k39N-2qveA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 GLU A  30
LEU A 216
ARG A  27
GLU A  31
ARG A 528
 None
 1.23A 3k39O-2qveA:
undetectable		 3k39O-2qveA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 GLU A  30
LEU A 216
ARG A  27
GLU A  31
ARG A 528
 None
 1.23A 3k39P-2qveA:
undetectable		 3k39P-2qveA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 GLY A 212
GLY A 209
LEU A 216
GLU A 334
ALA A 112
 None
 0.92A 3kkzA-2qveA:
undetectable		 3kkzA-2qveA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 7 TYR A 494
PHE A 483
VAL A 477
GLY A 481
 None
 1.11A 3kmoB-2qveA:
undetectable		 3kmoB-2qveA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 LEU A  20
LEU A 335
SER A 208
VAL A  15
LEU A 129
 None
 1.29A 3m7rA-2qveA:
undetectable		 3m7rA-2qveA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 LEU A 216
LEU A 136
ILE A 109
ALA A 112
LEU A 335
 None
 0.98A 3n8zB-2qveA:
undetectable		 3n8zB-2qveA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_2
(GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 9 ALA A 379
GLN A 382
ILE A 383
THR A 263
GLU A 229
 None
 1.35A 3qelD-2qveA:
undetectable		 3qelD-2qveA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 8 ASP A 262
GLY A 259
GLN A 537
ARG A 328
 None
 0.96A 3s3mA-2qveA:
undetectable		 3s3mA-2qveA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 6 LEU A 270
MET A 267
THR A 263
ARG A 321
 None
 1.37A 3thrB-2qveA:
undetectable		 3thrB-2qveA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 ARG A 328
GLU A 229
ARG A 321
ASN A 266
TYR A 325
 None
 1.28A 3ticA-2qveA:
undetectable		 3ticA-2qveA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_C_SVRC516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 9 GLY A 412
ALA A 413
ALA A 511
ASP A 513
LEU A 471
 None
 1.14A 3ur0C-2qveA:
undetectable		 3ur0C-2qveA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 4 LEU A 276
ILE A 479
TYR A 494
TYR A 393
 None
 1.40A 3vt7A-2qveA:
1.4		 3vt7A-2qveA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_1
(NEURAMINIDASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 ARG A 328
GLU A 229
ARG A 321
ASN A 266
TYR A 325
 None
 1.30A 4b7qA-2qveA:
undetectable		 4b7qA-2qveA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_B_ZMRB601_1
(NEURAMINIDASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 ARG A 328
GLU A 229
ARG A 321
ASN A 266
TYR A 325
 None
 1.25A 4b7qB-2qveA:
undetectable		 4b7qB-2qveA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 ARG A 328
GLU A 229
ARG A 321
ASN A 266
TYR A 325
 None
 1.39A 4cpzD-2qveA:
undetectable		 4cpzD-2qveA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 ARG A 328
GLU A 229
ARG A 321
ASN A 266
TYR A 325
 None
 1.36A 4cpzH-2qveA:
undetectable		 4cpzH-2qveA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 LEU A 372
LEU A 375
LEU A 378
ALA A 379
GLN A 382
 None
 0.58A 4fn9A-2qveA:
undetectable		 4fn9A-2qveA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 LEU A 372
LEU A 375
LEU A 378
ALA A 379
GLN A 382
 None
 0.54A 4fn9B-2qveA:
undetectable		 4fn9B-2qveA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 GLU A 138
ILE A 140
LEU A 132
VAL A 110
ALA A 111
 None
 1.25A 4fqsB-2qveA:
undetectable		 4fqsB-2qveA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 GLY A 212
GLY A 209
ILE A 361
VAL A  25
LEU A 335
 None
 1.01A 4gc9A-2qveA:
undetectable		 4gc9A-2qveA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 5 LEU A 335
ARG A  27
PRO A  38
SER A  41
 None
 1.17A 4kmmB-2qveA:
undetectable		 4kmmB-2qveA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		6 / 12 LEU A 372
LEU A 375
LEU A 378
ALA A 379
GLN A 382
LEU A 521
 None
 1.09A 4ltwA-2qveA:
undetectable		 4ltwA-2qveA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 ALA A 413
TYR A 415
PHE A 398
VAL A 400
GLY A 409
 None
 1.23A 4mm6A-2qveA:
undetectable		 4mm6A-2qveA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 8 GLU A 380
LEU A 471
VAL A 386
LEU A 387
 None
 0.96A 4r38B-2qveA:
undetectable		 4r38B-2qveA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		3 / 3 SER A 487
GLU A 279
GLU A 249
 None
 0.71A 4ymgB-2qveA:
undetectable		 4ymgB-2qveA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 10 ALA A 228
GLU A 229
ARG A 321
GLY A 524
LEU A 521
 None
 1.22A 5dxbA-2qveA:
undetectable		 5dxbA-2qveA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 7 VAL A 368
ALA A 455
GLY A 214
VAL A 218
 None
 0.87A 5fpdB-2qveA:
undetectable		 5fpdB-2qveA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		3 / 3 GLN A 475
THR A 503
ASP A 478
 None
 0.86A 5k9dA-2qveA:
undetectable		 5k9dA-2qveA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 8 LEU A 527
LEU A 222
ILE A 313
GLN A 382
 None
 0.97A 5ljbA-2qveA:
undetectable		 5ljbA-2qveA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		5 / 12 GLU A 515
ASP A 519
LEU A 372
GLN A 226
GLY A 524
 None
 1.24A 5syeB-2qveA:
undetectable		 5syeB-2qveA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		3 / 3 ARG A 321
PHE A 367
LEU A 372
 None
 0.70A 5veuA-2qveA:
undetectable		 5veuA-2qveA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 5 HIS A 357
ALA A 362
SER A 446
GLY A 151
 MDO  A 152 ( 4.1A)
None
MDO  A 152 ( 4.4A)
MDO  A 152 ( 2.4A)
 1.18A 5yodD-2qveA:
undetectable		 5yodD-2qveA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 6 LEU A 459
GLN A 224
LEU A 222
LEU A 324
 None
 1.10A 5yvnA-2qveA:
1.7		 5yvnA-2qveA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 6 SER A 149
ALA A 430
ALA A 452
SER A 451
 MDO  A 152 ( 4.0A)
None
None
None
 0.88A 6bocA-2qveA:
undetectable
6bocB-2qveA:
undetectable
6bocC-2qveA:
undetectable
6bocD-2qveA:
undetectable		 6bocA-2qveA:
4.36
6bocB-2qveA:
4.36
6bocC-2qveA:
4.36
6bocD-2qveA:
4.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 2qve TYROSINE AMINOMUTASE
(Streptomyces
globisporus) 		4 / 4 ARG A  49
GLU A  53
GLU A  82
ARG A 196
 None
 1.32A 6fk2A-2qveA:
undetectable		 6fk2A-2qveA:
14.29