SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qw6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FM6_U_9CRU502_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2qw6	AAA ATPASE, CENTRAL REGION (Enterococcus faecium)	5 / 12	ALA A 313 ALA A 305 LEU A 310 ILE A 244 LEU A 279	None	1.04A	1fm6U-2qw6A: undetectable	1fm6U-2qw6A: 19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WDM_C_ADNC301_1 (4-PHOSPHOPANTOATE--B ETA-ALANINE LIGASE)	2qw6	AAA ATPASE, CENTRAL REGION (Enterococcus faecium)	5 / 9	ALA A 304 GLY A 309 LEU A 317 LEU A 310 ILE A 275	None	1.19A	3wdmC-2qw6A: undetectable	3wdmC-2qw6A: 17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y0Q_A_PX9A201_0 (BETA-LACTOGLOBULIN)	2qw6	AAA ATPASE, CENTRAL REGION (Enterococcus faecium)	5 / 12	LEU A 317 VAL A 320 ILE A 282 LEU A 324 PHE A 247	None	1.11A	4y0qA-2qw6A: undetectable	4y0qA-2qw6A: 19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CVT_B_ACTB200_0 (N5-CARBOXYAMINOIMIDA ZOLE RIBONUCLEOTIDE MUTASE)	2qw6	AAA ATPASE, CENTRAL REGION (Enterococcus faecium)	3 / 3	ASN A 291 ALA A 293 ARG A 297	None	0.31A	5cvtB-2qw6A: undetectable	5cvtB-2qw6A: 25.54

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FM6_U_9CRU502_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2qw6","AAA ATPASE, CENTRAL REGION","Enterococcus faecium",5,"ALA A 313;ALA A 305;LEU A 310;ILE A 244;LEU A 279","None","1.04A","1fm6U-2qw6A:undetectable","1fm6U-2qw6A:19.33"],["3WDM_C_ADNC301_1","4-PHOSPHOPANTOATE--BETA-ALANINE LIGASE","2qw6","AAA ATPASE, CENTRAL REGION","Enterococcus faecium",5,"ALA A 304;GLY A 309;LEU A 317;LEU A 310;ILE A 275","None","1.19A","3wdmC-2qw6A:undetectable","3wdmC-2qw6A:17.31"],["4Y0Q_A_PX9A201_0","BETA-LACTOGLOBULIN","2qw6","AAA ATPASE, CENTRAL REGION","Enterococcus faecium",5,"LEU A 317;VAL A 320;ILE A 282;LEU A 324;PHE A 247","None","1.11A","4y0qA-2qw6A:undetectable","4y0qA-2qw6A:19.63"],["5CVT_B_ACTB200_0","N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE MUTASE","2qw6","AAA ATPASE, CENTRAL REGION","Enterococcus faecium",3,"ASN A 291;ALA A 293;ARG A 297","None","0.31A","5cvtB-2qw6A:undetectable","5cvtB-2qw6A:25.54"]]