SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qwv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2qwv UPF0217 PROTEIN
VC_A1059
(Vibrio
cholerae) 		5 / 11 LEU A  90
LEU A  57
ALA A 187
VAL A  71
LEU A  43
 None
 1.13A 1kt7A-2qwvA:
undetectable		 1kt7A-2qwvA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_A_VDNA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 2qwv UPF0217 PROTEIN
VC_A1059
(Vibrio
cholerae) 		5 / 12 MET A 136
LEU A 180
ILE A 146
GLN A 201
ILE A 194
 ACY  A 301 ( 4.9A)
ACY  A 301 (-4.1A)
None
None
None
 1.09A 1xotA-2qwvA:
undetectable		 1xotA-2qwvA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2qwv UPF0217 PROTEIN
VC_A1059
(Vibrio
cholerae) 		4 / 5 LEU A 123
THR A  68
GLU A 126
HIS A 131
 None
 1.36A 3n58C-2qwvA:
undetectable		 3n58C-2qwvA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2qwv UPF0217 PROTEIN
VC_A1059
(Vibrio
cholerae) 		5 / 12 GLU A 104
ILE A 118
SER A 119
GLU A 121
GLU A  60
 None
 1.43A 3r75A-2qwvA:
undetectable		 3r75A-2qwvA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2qwv UPF0217 PROTEIN
VC_A1059
(Vibrio
cholerae) 		5 / 12 GLU A 104
ILE A 118
SER A 119
GLU A 121
GLU A  60
 None
 1.46A 3r75B-2qwvA:
undetectable		 3r75B-2qwvA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2qwv UPF0217 PROTEIN
VC_A1059
(Vibrio
cholerae) 		5 / 11 GLU A 104
ILE A 118
SER A 119
GLU A 121
GLU A  60
 None
 1.45A 3r76A-2qwvA:
undetectable		 3r76A-2qwvA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2qwv UPF0217 PROTEIN
VC_A1059
(Vibrio
cholerae) 		5 / 11 GLU A 104
ILE A 118
SER A 119
GLU A 121
GLU A  60
 None
 1.41A 3r76B-2qwvA:
undetectable		 3r76B-2qwvA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 2qwv UPF0217 PROTEIN
VC_A1059
(Vibrio
cholerae) 		3 / 3 GLU A 176
TYR A 134
SER A 132
 None
 0.94A 4at0A-2qwvA:
undetectable		 4at0A-2qwvA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 2qwv UPF0217 PROTEIN
VC_A1059
(Vibrio
cholerae) 		4 / 4 LEU A 127
ILE A 155
GLY A 125
PHE A 120
 None
 1.07A 4dc3A-2qwvA:
undetectable		 4dc3A-2qwvA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K88_A_HFGA602_0
(PROLINE--TRNA LIGASE)		 2qwv UPF0217 PROTEIN
VC_A1059
(Vibrio
cholerae) 		5 / 12 VAL A 108
THR A  70
ARG A 116
HIS A 131
SER A   7
 None
 1.33A 4k88A-2qwvA:
2.6		 4k88A-2qwvA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2qwv UPF0217 PROTEIN
VC_A1059
(Vibrio
cholerae) 		4 / 8 ILE A  69
SER A   7
LEU A 127
LEU A 124
 None
 0.97A 4xtaB-2qwvA:
undetectable		 4xtaB-2qwvA:
23.40