SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qww'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 2qww TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Listeria
monocytogenes) 		5 / 12 LEU A  83
VAL A  84
SER A 103
SER A 110
LEU A  64
 None
 1.14A 1db1A-2qwwA:
undetectable		 1db1A-2qwwA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_PNTA901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 2qww TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Listeria
monocytogenes) 		5 / 12 THR A  39
GLY A  82
SER A 103
VAL A  84
ASN A  74
 None
 1.42A 3hiiA-2qwwA:
undetectable		 3hiiA-2qwwA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_PNTB901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 2qww TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Listeria
monocytogenes) 		5 / 12 THR A  39
GLY A  82
SER A 103
VAL A  84
ASN A  74
 None
 1.47A 3hiiB-2qwwA:
undetectable		 3hiiB-2qwwA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2qww TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Listeria
monocytogenes) 		5 / 12 LEU A  83
VAL A  84
SER A 103
SER A 110
LEU A  64
 None
 1.14A 3vt3A-2qwwA:
undetectable		 3vt3A-2qwwA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2qww TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Listeria
monocytogenes) 		5 / 12 LEU A  83
VAL A  84
SER A 103
SER A 110
LEU A  64
 None
 1.15A 3vt7A-2qwwA:
undetectable		 3vt7A-2qwwA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 2qww TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Listeria
monocytogenes) 		4 / 7 LEU A  43
ASN A  47
LEU A  83
ILE A  55
 None
 1.04A 4okwA-2qwwA:
undetectable		 4okwA-2qwwA:
20.88