SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qwz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 2qwz PHENYLACETIC ACID
DEGRADATION-RELATED
PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 11 GLU A  15
GLY A   9
ALA A  12
ALA A  71
ASP A   8
 None
 1.23A 3nmuB-2qwzA:
undetectable
3nmuJ-2qwzA:
undetectable		 3nmuB-2qwzA:
19.12
3nmuJ-2qwzA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 2qwz PHENYLACETIC ACID
DEGRADATION-RELATED
PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 7 VAL A  52
SER A 120
MET A  57
LEU A  60
 ACT  A 141 ( 4.0A)
None
None
None
 1.20A 4hxyB-2qwzA:
undetectable		 4hxyB-2qwzA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2qwz PHENYLACETIC ACID
DEGRADATION-RELATED
PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 4 LEU A  98
LEU A 118
SER A  56
ALA A  61
 None
None
ACT  A 141 (-2.7A)
None
 1.07A 5uunA-2qwzA:
undetectable		 5uunA-2qwzA:
20.49