SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qx2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		3 / 3 GLU A 297
ALA A 292
SER A 289
 None
 0.60A 1errB-2qx2A:
undetectable		 1errB-2qx2A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		3 / 3 LYS A 218
ASP A 328
ASN A 279
 None
 0.96A 2bm9A-2qx2A:
undetectable		 2bm9A-2qx2A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		5 / 12 PHE A 173
GLN A 171
LEU A 229
HIS A 244
LEU A  86
 None
 1.47A 3adxA-2qx2A:
undetectable		 3adxA-2qx2A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_B_PNNB5002_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		4 / 5 ASN A 300
ALA A 293
ALA A 292
LYS A 283
 None
 1.37A 3kp2B-2qx2A:
0.5		 3kp2B-2qx2A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		4 / 5 GLU A  83
GLY A  79
TYR A 248
GLN A 250
 EDO  A   1 ( 4.0A)
EDO  A   1 (-4.2A)
None
None
 1.20A 3w9tD-2qx2A:
undetectable		 3w9tD-2qx2A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		4 / 8 ILE A 373
ILE A 340
GLN A 345
GLY A 344
 None
None
None
EDO  A 402 ( 3.7A)
 0.79A 4acaC-2qx2A:
undetectable		 4acaC-2qx2A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		4 / 8 ILE A 373
ILE A 340
GLN A 345
GLY A 344
 None
None
None
EDO  A 402 ( 3.7A)
 0.83A 4acbC-2qx2A:
undetectable		 4acbC-2qx2A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		4 / 6 LYS A 325
LEU A 286
SER A 289
THR A 291
 None
 1.06A 4ikiB-2qx2A:
undetectable		 4ikiB-2qx2A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		4 / 7 LYS A 325
LEU A 286
SER A 289
THR A 291
 None
 1.01A 4ikjA-2qx2A:
undetectable
4ikjB-2qx2A:
undetectable		 4ikjA-2qx2A:
16.37
4ikjB-2qx2A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		4 / 8 GLY A 186
TYR A 101
PHE A  94
SER A  90
 None
None
EDO  A 400 ( 4.7A)
None
 0.92A 4wryA-2qx2A:
undetectable		 4wryA-2qx2A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		4 / 8 GLY A 186
TYR A 101
PHE A  94
SER A  90
 None
None
EDO  A 400 ( 4.7A)
None
 0.97A 4wrzA-2qx2A:
undetectable		 4wrzA-2qx2A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		4 / 8 GLY A 186
TYR A 101
PHE A  94
SER A  90
 None
None
EDO  A 400 ( 4.7A)
None
 0.94A 4ws1A-2qx2A:
undetectable		 4ws1A-2qx2A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		4 / 4 VAL A 394
ALA A 381
ILE A 349
THR A 348
 None
 1.00A 5e4dB-2qx2A:
undetectable		 5e4dB-2qx2A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		4 / 6 LYS A 323
LEU A 287
PHE A 306
LEU A 299
 None
 1.12A 5w97C-2qx2A:
undetectable
5w97J-2qx2A:
undetectable		 5w97C-2qx2A:
19.43
5w97J-2qx2A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		4 / 7 VAL A 355
PRO A 392
ILE A 373
THR A 348
 None
 0.97A 6cduF-2qx2A:
undetectable
6cduG-2qx2A:
undetectable		 6cduF-2qx2A:
19.67
6cduG-2qx2A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		4 / 8 VAL A 355
PRO A 392
ILE A 373
THR A 348
 None
 1.02A 6cduG-2qx2A:
undetectable
6cduH-2qx2A:
undetectable		 6cduG-2qx2A:
19.67
6cduH-2qx2A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 2qx2 SEX PHEROMONE
STAPH-CAM373
(Staphylococcus
aureus) 		5 / 12 GLU A 227
LEU A  86
ALA A 225
PHE A 245
LEU A 232
 None
None
None
None
EDO  A 401 ( 4.9A)
 1.14A 6ew0G-2qx2A:
undetectable		 6ew0G-2qx2A:
11.25