SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qxy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 2qxy RESPONSE REGULATOR
(Thermotoga
maritima) 		3 / 3 GLN A  38
LYS A  35
VAL A  10
 None
 0.82A 2jfaB-2qxyA:
undetectable		 2jfaB-2qxyA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 2qxy RESPONSE REGULATOR
(Thermotoga
maritima) 		5 / 12 ILE A  69
PHE A  43
LEU A  44
VAL A  78
VAL A  10
 None
 1.10A 2vn0A-2qxyA:
undetectable		 2vn0A-2qxyA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 2qxy RESPONSE REGULATOR
(Thermotoga
maritima) 		4 / 6 VAL A 115
PHE A  53
VAL A  31
PHE A 106
 None
 0.97A 3soaA-2qxyA:
undetectable		 3soaA-2qxyA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2qxy RESPONSE REGULATOR
(Thermotoga
maritima) 		5 / 12 GLU A  61
PHE A  41
LEU A  44
ILE A  32
ARG A  68
 None
 1.21A 4hytA-2qxyA:
3.8		 4hytA-2qxyA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 2qxy RESPONSE REGULATOR
(Thermotoga
maritima) 		4 / 6 PHE A  17
LYS A  21
LEU A  24
ARG A  14
 None
 1.04A 4yv5B-2qxyA:
undetectable		 4yv5B-2qxyA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 2qxy RESPONSE REGULATOR
(Thermotoga
maritima) 		4 / 6 PHE A  17
LYS A  21
LEU A  24
ARG A  14
 None
 1.07A 4yv5A-2qxyA:
undetectable		 4yv5A-2qxyA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 2qxy RESPONSE REGULATOR
(Thermotoga
maritima) 		5 / 12 LEU A  18
ALA A  19
PHE A  17
PHE A 106
LEU A 111
 None
 1.19A 5k9dA-2qxyA:
2.9		 5k9dA-2qxyA:
19.19