SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qy0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		6 / 8 HIS B 485
ASP B 631
SER B 637
VAL B 657
GLY B 660
GLY B 668
 None
 0.64A 1aq7A-2qy0B:
31.7		 1aq7A-2qy0B:
32.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		7 / 9 ASP B 631
ALA B 632
SER B 637
VAL B 657
TRP B 659
GLY B 660
GLY B 668
 None
 0.37A 1bcuH-2qy0B:
34.0		 1bcuH-2qy0B:
38.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DWC_H_MITH1_1
(ALPHA-THROMBIN
(LARGE SUBUNIT))		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		5 / 9 HIS B 485
ASP B 631
SER B 637
TRP B 659
GLY B 668
 None
 0.27A 1dwcH-2qy0B:
32.9		 1dwcH-2qy0B:
38.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETR_H_MITH1_1
(EPSILON-THROMBIN)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		7 / 12 HIS B 485
ASP B 631
SER B 637
VAL B 657
TRP B 659
GLY B 660
GLY B 668
 None
 0.47A 1etrH-2qy0B:
32.8		 1etrH-2qy0B:
38.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		6 / 8 ASP B 631
GLN B 634
SER B 637
VAL B 657
GLY B 660
GLY B 668
 None
 0.53A 1f5lA-2qy0B:
30.5		 1f5lA-2qy0B:
30.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		5 / 11 TYR B 568
PHE B 567
VAL B 643
ILE B 656
PHE B 621
 None
 1.29A 1tcoC-2qy0B:
undetectable		 1tcoC-2qy0B:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TNL_A_TPAA900_1
(TRYPSIN)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		5 / 6 ASP B 631
SER B 637
VAL B 657
GLY B 660
GLY B 668
 None
 0.47A 1tnlA-2qy0B:
32.0		 1tnlA-2qy0B:
32.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 7 GLY B 472
GLY B 639
VAL B 502
LEU B 544
 None
 0.79A 2oa1B-2qy0B:
undetectable		 2oa1B-2qy0B:
19.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTV_A_NCAA1301_0
(CATIONIC TRYPSIN)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		5 / 6 ASP B 631
SER B 637
VAL B 657
GLY B 660
GLY B 668
 None
 0.43A 2otvA-2qy0B:
32.1		 2otvA-2qy0B:
32.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		8 / 12 ASP B 631
ALA B 632
SER B 637
VAL B 657
TRP B 659
GLY B 660
GLY B 668
TYR B 670
 None
 0.43A 2p16A-2qy0B:
32.2		 2p16A-2qy0B:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		6 / 8 ASP B 631
GLN B 634
SER B 637
VAL B 657
GLY B 660
GLY B 668
 None
 0.60A 2vinA-2qy0B:
31.1		 2vinA-2qy0B:
30.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		9 / 12 ASP B 631
ALA B 632
SER B 637
VAL B 657
TRP B 659
GLY B 660
GLY B 662
GLY B 668
TYR B 670
 None
 0.48A 2w26A-2qy0B:
32.2		 2w26A-2qy0B:
40.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		5 / 12 LEU B 590
VAL B 581
GLY B 580
GLY B 578
PHE B 592
 None
 1.23A 3dh0A-2qy0B:
undetectable		 3dh0A-2qy0B:
21.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		6 / 11 HIS B 485
ASP B 631
SER B 637
TRP B 659
GLY B 660
GLY B 668
 None
 0.45A 3gy3A-2qy0B:
11.7		 3gy3A-2qy0B:
32.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 6 GLY B 638
GLN B 461
ILE B 656
VAL B 657
 None
 1.14A 3kvvA-2qy0B:
undetectable		 3kvvA-2qy0B:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 6 GLY B 638
GLN B 461
ILE B 656
VAL B 657
 None
 1.13A 3kvvB-2qy0B:
undetectable		 3kvvB-2qy0B:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 6 GLY B 638
GLN B 461
ILE B 656
VAL B 657
 None
 1.15A 3kvvC-2qy0B:
undetectable		 3kvvC-2qy0B:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 6 GLY B 638
GLN B 461
ILE B 656
VAL B 657
 None
 1.11A 3kvvD-2qy0B:
undetectable		 3kvvD-2qy0B:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 6 GLY B 638
GLN B 461
ILE B 656
VAL B 657
 None
 1.13A 3kvvE-2qy0B:
undetectable		 3kvvE-2qy0B:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 6 GLY B 638
GLN B 461
ILE B 656
VAL B 657
 None
 1.11A 3kvvF-2qy0B:
undetectable		 3kvvF-2qy0B:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		5 / 11 TYR B 568
PHE B 567
VAL B 643
ILE B 656
PHE B 621
 None
 1.15A 3o5rA-2qy0B:
undetectable		 3o5rA-2qy0B:
19.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		5 / 6 SER B 637
VAL B 657
TRP B 659
GLY B 660
GLY B 668
 None
 0.22A 3rxfA-2qy0B:
13.2		 3rxfA-2qy0B:
32.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 5 ASP B 631
SER B 637
VAL B 657
GLY B 668
 None
 0.57A 3rxhA-2qy0B:
32.0		 3rxhA-2qy0B:
32.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 6 GLY B 638
GLN B 461
ILE B 656
VAL B 657
 None
 1.14A 4e1vF-2qy0B:
undetectable		 4e1vF-2qy0B:
22.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 5 HIS B 485
GLN B 634
GLY B 635
SER B 637
 None
 0.56A 4fu8A-2qy0B:
30.6		 4fu8A-2qy0B:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HFP_D_15UD402_1
(PROTHROMBIN)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		6 / 12 HIS B 485
ASP B 631
ALA B 632
VAL B 657
TRP B 659
GLY B 668
 None
 0.32A 4hfpD-2qy0B:
32.8		 4hfpD-2qy0B:
37.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 5 GLY B 472
LEU B 546
LEU B 556
LEU B 561
 None
None
None
GOL  B 801 (-4.3A)
 0.84A 4o8fA-2qy0B:
undetectable		 4o8fA-2qy0B:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		5 / 12 VAL B 673
GLY B 472
ILE B 541
LEU B 543
LEU B 474
 None
 1.02A 4qdjA-2qy0B:
undetectable		 4qdjA-2qy0B:
21.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		5 / 12 HIS B 485
VAL B 657
TRP B 659
GLY B 660
GLY B 668
 None
 0.29A 4rn6B-2qy0B:
27.7		 4rn6B-2qy0B:
37.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 4 PHE B 641
VAL B 576
ALA B 642
PHE B 458
 None
 1.45A 4w5qA-2qy0B:
undetectable		 4w5qA-2qy0B:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		3 / 3 ALA B 642
TRP B 651
VAL B 652
 None
 0.42A 4w9nC-2qy0B:
undetectable		 4w9nC-2qy0B:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 5 GLY B 539
TYR B 670
SER B 658
GLU B 538
 None
 1.08A 4xueA-2qy0B:
undetectable		 4xueA-2qy0B:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 4 PHE B 641
VAL B 576
ALA B 642
PHE B 458
 None
 1.49A 4z4gA-2qy0B:
undetectable		 4z4gA-2qy0B:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 8 SER B 577
GLY B 578
GLY B 470
PHE B 579
 None
 0.92A 5albL-2qy0B:
undetectable		 5albL-2qy0B:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 5 VAL B 523
LEU B 487
HIS B 467
THR B 482
 None
 1.38A 6dyoA-2qy0B:
undetectable		 6dyoA-2qy0B:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		3 / 3 ARG B 591
PHE B 592
GLY B 450
 None
 0.76A 6fgdA-2qy0B:
undetectable		 6fgdA-2qy0B:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2qy0 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 7 ILE B 541
GLY B 578
ARG B 478
ALA B 473
 None
 0.83A 6hd6B-2qy0B:
undetectable		 6hd6B-2qy0B:
17.18