SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qy1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 GLY A 110
VAL A 154
ILE A 178
VAL A 120
ILE A 122
 None
 0.88A 1hsgB-2qy1A:
undetectable		 1hsgB-2qy1A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 THR A  33
GLY A  35
GLY A  61
GLY A  60
VAL A  63
 None
 0.95A 1n2xB-2qy1A:
undetectable		 1n2xB-2qy1A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		3 / 3 ASN A 291
ALA A 334
ASN A 243
 None
 0.80A 1n4fA-2qy1A:
undetectable		 1n4fA-2qy1A:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 VAL A  89
ILE A 127
ILE A 139
VAL A 184
ILE A 152
 None
 1.17A 1r5lA-2qy1A:
undetectable		 1r5lA-2qy1A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 GLY A 110
VAL A 154
ILE A 178
VAL A 120
ILE A 122
 None
 0.99A 1sdtB-2qy1A:
undetectable		 1sdtB-2qy1A:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 LEU A  64
ILE A 122
ILE A 139
VAL A  97
ILE A  99
 None
 0.92A 2hs1B-2qy1A:
undetectable		 2hs1B-2qy1A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 GLY A 110
VAL A 154
ILE A 178
VAL A 120
ILE A 122
 None
 0.89A 2o4kB-2qy1A:
undetectable		 2o4kB-2qy1A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 GLY A 110
VAL A 154
ILE A 178
VAL A 120
ILE A 122
 None
 0.90A 2o4lB-2qy1A:
undetectable		 2o4lB-2qy1A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 GLY A 110
VAL A 154
ILE A 178
VAL A 120
ILE A 122
 None
 0.93A 2q63B-2qy1A:
undetectable		 2q63B-2qy1A:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 GLY A 110
VAL A 154
ILE A 178
VAL A 120
ILE A 122
 None
 0.94A 2qakB-2qy1A:
undetectable		 2qakB-2qy1A:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 SER A 190
ASN A 192
THR A 188
LEU A 141
ILE A 139
 None
 0.84A 2xrlA-2qy1A:
undetectable		 2xrlA-2qy1A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		4 / 6 ARG A 230
ASP A 175
GLN A  90
GLU A 142
 None
 1.02A 2ya7C-2qy1A:
undetectable		 2ya7C-2qy1A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 THR A 217
ASN A 212
MET A 180
ILE A 178
VAL A 227
 None
 1.42A 3a51B-2qy1A:
undetectable		 3a51B-2qy1A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		4 / 7 ASP A 209
SER A 206
GLU A 134
ASP A 135
 None
 1.22A 3bc9A-2qy1A:
undetectable		 3bc9A-2qy1A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		4 / 7 TYR A 197
ILE A 127
GLY A 176
VAL A 154
 None
 0.92A 3elzA-2qy1A:
undetectable		 3elzA-2qy1A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 LYS A 338
ASN A 271
GLY A 295
SER A 296
GLY A 297
 None
 1.05A 3huoB-2qy1A:
undetectable		 3huoB-2qy1A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 ILE A 178
GLY A 177
GLY A 176
ALA A 136
VAL A 159
 None
 0.89A 3jb2A-2qy1A:
undetectable		 3jb2A-2qy1A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 GLY A 110
VAL A 154
ILE A 178
VAL A 120
ILE A 122
 None
 0.93A 3jvyB-2qy1A:
undetectable		 3jvyB-2qy1A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		3 / 3 ARG A 223
THR A 188
THR A 332
 None
 0.80A 3k2hB-2qy1A:
undetectable		 3k2hB-2qy1A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 GLY A 110
VAL A 154
ILE A 178
VAL A 120
ILE A 122
 None
 0.95A 3pwrB-2qy1A:
undetectable		 3pwrB-2qy1A:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		4 / 5 ILE A 264
TRP A 315
TRP A 300
THR A 250
 None
 1.34A 3topA-2qy1A:
undetectable		 3topA-2qy1A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_2
(ADENOSINE KINASE,
PUTATIVE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		4 / 5 LEU A 130
ALA A 107
PHE A 109
ASN A 157
 None
 1.41A 3uq6A-2qy1A:
undetectable		 3uq6A-2qy1A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		4 / 4 LEU A 130
ALA A 107
PHE A 109
ASN A 157
 None
 1.49A 3vaqA-2qy1A:
undetectable		 3vaqA-2qy1A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		4 / 4 LEU A 130
ALA A 107
PHE A 109
ASN A 157
 None
 1.46A 3vasA-2qy1A:
undetectable		 3vasA-2qy1A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		4 / 5 THR A  74
ILE A  75
LYS A  76
PHE A 160
 None
 1.24A 4ac9C-2qy1A:
undetectable		 4ac9C-2qy1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		4 / 5 THR A  74
ILE A  75
LYS A  76
PHE A 160
 None
 1.24A 4acaC-2qy1A:
undetectable		 4acaC-2qy1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		4 / 5 THR A  74
ILE A  75
LYS A  76
PHE A 160
 None
 1.26A 4acbC-2qy1A:
undetectable		 4acbC-2qy1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 GLY A  24
LEU A 351
ASN A 124
SER A 190
TYR A 191
 None
 1.23A 4f84A-2qy1A:
undetectable		 4f84A-2qy1A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 LEU A  64
ILE A 122
ILE A 139
GLY A 110
ILE A  99
 None
 0.93A 4q1xB-2qy1A:
undetectable		 4q1xB-2qy1A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 LEU A  64
ILE A 122
ILE A 139
VAL A  97
ILE A  99
 None
 0.65A 4q1xB-2qy1A:
undetectable		 4q1xB-2qy1A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 LEU A  64
ILE A 122
ILE A 139
VAL A  97
ILE A  99
 None
 0.78A 4q1yB-2qy1A:
undetectable		 4q1yB-2qy1A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		6 / 12 LEU A 141
GLY A 183
ALA A 215
ILE A 152
THR A 217
VAL A 189
 None
 1.38A 4xdrA-2qy1A:
undetectable		 4xdrA-2qy1A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		3 / 3 GLU A 353
THR A 188
HIS A 220
 None
 0.83A 4ydqB-2qy1A:
undetectable		 4ydqB-2qy1A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 LEU A 233
GLY A 176
ASN A 222
THR A 188
ASN A 203
 None
 1.19A 5d0yA-2qy1A:
undetectable		 5d0yA-2qy1A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_A_BEZA201_0
(HYDROXYNITRILE LYASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 9 VAL A 227
VAL A 249
PHE A 246
ILE A 254
TYR A 219
 None
 1.30A 5e4dA-2qy1A:
undetectable		 5e4dA-2qy1A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		6 / 11 VAL A 227
VAL A 249
PHE A 246
ILE A 241
ILE A 254
TYR A 219
 None
 1.26A 5e4dB-2qy1A:
undetectable		 5e4dB-2qy1A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 TYR A 329
ILE A 298
PHE A 246
GLY A 253
HIS A 240
 None
 1.32A 5esgA-2qy1A:
undetectable		 5esgA-2qy1A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		3 / 3 LYS A  92
ASN A  93
SER A 146
 None
 1.23A 5yw0A-2qy1A:
undetectable		 5yw0A-2qy1A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 2qy1 PECTATE LYASE II
(Xanthomonas
campestris) 		5 / 12 GLY A 110
VAL A 154
ILE A 178
VAL A 120
ILE A 122
 None
 0.88A 6difB-2qy1A:
undetectable		 6difB-2qy1A:
13.62