SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qy6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 4 HIS A 136
LEU A  31
LEU A 125
LEU A 147
 None
 1.22A 1a4lD-2qy6A:
undetectable		 1a4lD-2qy6A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 8 GLU A  84
GLY A  86
GLU A 121
ASP A 176
 None
 0.54A 1jg4A-2qy6A:
6.8		 1jg4A-2qy6A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLU A  84
GLY A  86
GLY A  88
ASP A 176
ILE A 177
 None
 0.61A 1qaoA-2qy6A:
7.1		 1qaoA-2qy6A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 7 PHE A 200
ASN A 205
TRP A 209
SER A  85
 None
 1.25A 1rqpB-2qy6A:
undetectable		 1rqpB-2qy6A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 10 ALA A  83
PHE A 117
LEU A  96
GLY A  64
PHE A  62
 None
 1.45A 1uhoA-2qy6A:
undetectable		 1uhoA-2qy6A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 10 ALA A  83
PHE A 117
LEU A  96
GLY A  65
PHE A  62
 None
 1.41A 1uhoA-2qy6A:
undetectable		 1uhoA-2qy6A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 8 ASP A 198
THR A  38
PRO A  39
LEU A  31
 None
 0.73A 1z2bB-2qy6A:
2.7		 1z2bB-2qy6A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		3 / 3 GLY A  86
GLU A 121
ASP A 198
 None
 0.34A 2b25B-2qy6A:
10.0		 2b25B-2qy6A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  88
LYS A 122
ASP A 176
ASP A 198
 None
 0.85A 2pxcA-2qy6A:
4.1		 2pxcA-2qy6A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 7 PHE A 200
ASN A 205
TRP A 209
SER A  85
 None
 1.27A 2v7uB-2qy6A:
undetectable		 2v7uB-2qy6A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		3 / 3 ASP A 198
THR A 126
GLU A 121
 None
 0.68A 2zifB-2qy6A:
2.0		 2zifB-2qy6A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  88
GLU A 121
LYS A 122
ASP A 176
 None
 0.45A 3fuuA-2qy6A:
9.9		 3fuuA-2qy6A:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  88
GLY A  90
ASP A 176
ILE A 177
 None
 0.60A 3ihtA-2qy6A:
11.0		 3ihtA-2qy6A:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  88
GLY A  90
ASP A 176
ILE A 177
ASP A 198
 None
 0.52A 3ihtA-2qy6A:
11.0		 3ihtA-2qy6A:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 8 GLY A  86
PHE A 100
PHE A  72
PHE A 117
 None
 1.08A 3ko0D-2qy6A:
undetectable
3ko0E-2qy6A:
undetectable		 3ko0D-2qy6A:
18.18
3ko0E-2qy6A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 8 PHE A 117
GLY A  86
PHE A 100
PHE A  72
 None
 1.10A 3ko0B-2qy6A:
undetectable
3ko0J-2qy6A:
undetectable		 3ko0B-2qy6A:
18.18
3ko0J-2qy6A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 7 GLY A  86
PHE A 100
PHE A  72
PHE A 117
 None
 1.11A 3ko0L-2qy6A:
undetectable
3ko0N-2qy6A:
undetectable		 3ko0L-2qy6A:
18.18
3ko0N-2qy6A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 7 PHE A 117
GLY A  86
PHE A 100
PHE A  72
 None
 1.10A 3ko0K-2qy6A:
undetectable
3ko0S-2qy6A:
undetectable		 3ko0K-2qy6A:
18.18
3ko0S-2qy6A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 7 PHE A 117
GLY A  86
PHE A 100
PHE A  72
 None
 1.10A 3ko0R-2qy6A:
undetectable
3ko0T-2qy6A:
undetectable		 3ko0R-2qy6A:
18.18
3ko0T-2qy6A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 4 GLY A  86
GLU A 121
ASP A 176
ASP A 198
 None
 0.63A 3mb5A-2qy6A:
11.2		 3mb5A-2qy6A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  88
LYS A 122
ASP A 176
ASP A 198
 None
 0.83A 3p97A-2qy6A:
5.6		 3p97A-2qy6A:
22.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		11 / 12 PHE A  44
GLU A  84
GLY A  86
ASN A  92
LYS A 122
PHE A 123
ASP A 176
ILE A 177
GLY A 199
PHE A 200
MET A 208
 None
 0.68A 3ps9A-2qy6A:
38.0		 3ps9A-2qy6A:
43.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		11 / 12 PHE A  44
GLU A  84
GLY A  86
ASN A  92
PHE A 123
ASP A 176
ILE A 177
GLY A 199
PHE A 200
ASN A 205
MET A 208
 None
 0.75A 3ps9A-2qy6A:
38.0		 3ps9A-2qy6A:
43.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PS9_A_SAMA670_1
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		6 / 6 TYR A  48
GLY A  88
THR A  89
LEU A  91
GLU A 121
ASP A 198
 None
 0.40A 3ps9A-2qy6A:
38.0		 3ps9A-2qy6A:
43.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		9 / 12 GLU A  84
GLY A  86
GLY A  88
THR A  89
LEU A  91
ASN A  92
LYS A 122
ASP A 176
GLY A 199
 None
 0.68A 3sglA-2qy6A:
33.3		 3sglA-2qy6A:
33.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		6 / 12 TYR A  48
GLY A  86
GLY A  88
ASN A  92
LYS A 122
PHE A 200
 None
 0.68A 3vywA-2qy6A:
23.1		 3vywA-2qy6A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 6 GLU A 121
ASP A 176
ASP A 198
ASN A 205
 None
 0.85A 3vywA-2qy6A:
23.1		 3vywA-2qy6A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  88
ASN A  92
LYS A 122
ASN A 205
 None
 1.02A 3vywB-2qy6A:
23.8		 3vywB-2qy6A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		6 / 12 TYR A  48
GLY A  86
GLY A  88
ASN A  92
PHE A 200
ASN A 205
 None
 0.62A 3vywB-2qy6A:
23.8		 3vywB-2qy6A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 TYR A  48
GLY A  86
GLY A  90
ASN A  92
PHE A 200
 None
 0.56A 3vywC-2qy6A:
23.3		 3vywC-2qy6A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 6 GLY A  88
GLU A 121
ASP A 176
ASP A 198
ASN A 205
 None
 0.67A 3vywC-2qy6A:
23.3		 3vywC-2qy6A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		6 / 12 TYR A  48
GLY A  86
GLY A  88
ASN A  92
LYS A 122
PHE A 200
 None
 0.62A 3vywD-2qy6A:
23.4		 3vywD-2qy6A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 5 GLU A 121
ASP A 176
ASP A 198
ASN A 205
 None
 0.81A 3vywD-2qy6A:
23.4		 3vywD-2qy6A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  88
LYS A 122
ASP A 176
ASP A 198
 None
 0.79A 4ctjA-2qy6A:
3.9		 4ctjA-2qy6A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  88
LYS A 122
ASP A 176
ASP A 198
 None
 0.79A 4ctkA-2qy6A:
5.4		 4ctkA-2qy6A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 HIS A 134
LEU A 140
GLY A 199
ASP A 198
THR A  95
 None
 1.42A 4mubA-2qy6A:
undetectable		 4mubA-2qy6A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  65
ASP A 198
ALA A 194
PHE A  80
VAL A  82
 None
 1.00A 4u8vB-2qy6A:
undetectable		 4u8vB-2qy6A:
12.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  65
ASP A 198
ALA A 194
PHE A  80
VAL A  82
 None
 1.00A 4u8yB-2qy6A:
undetectable		 4u8yB-2qy6A:
12.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 7 GLY A 262
ARG A  71
GLY A 225
ALA A 228
 None
 0.91A 5e26A-2qy6A:
undetectable
5e26B-2qy6A:
undetectable		 5e26A-2qy6A:
22.45
5e26B-2qy6A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 7 ALA A 228
GLY A 262
ARG A  71
GLY A 225
 None
 0.87A 5e26A-2qy6A:
undetectable
5e26B-2qy6A:
undetectable		 5e26A-2qy6A:
22.45
5e26B-2qy6A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 8 ALA A 228
GLY A 262
ARG A  71
GLY A 225
 None
 0.88A 5e26C-2qy6A:
undetectable
5e26D-2qy6A:
undetectable		 5e26C-2qy6A:
22.45
5e26D-2qy6A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  88
LYS A 122
ASP A 176
ASP A 198
 None
 0.85A 5e9qA-2qy6A:
5.5		 5e9qA-2qy6A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  88
LYS A 122
ASP A 176
ASP A 198
 None
 0.79A 5ehgA-2qy6A:
5.6		 5ehgA-2qy6A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  88
LYS A 122
ASP A 176
ASP A 198
 None
 0.80A 5eifA-2qy6A:
3.8		 5eifA-2qy6A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 7 GLY A  86
GLY A  88
GLU A 121
ASP A 176
 None
 0.58A 5ergB-2qy6A:
9.4		 5ergB-2qy6A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 7 GLY A  86
GLY A  88
GLU A 121
ASP A 198
 None
 0.41A 5ergB-2qy6A:
9.4		 5ergB-2qy6A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 5 LEU A 115
PHE A 103
LEU A  96
PHE A 196
 None
 1.24A 5iy5P-2qy6A:
undetectable
5iy5W-2qy6A:
undetectable		 5iy5P-2qy6A:
21.65
5iy5W-2qy6A:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 8 GLY A  86
GLU A 121
LYS A 122
ASP A 176
 None
 0.66A 5mvsB-2qy6A:
9.1		 5mvsB-2qy6A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		4 / 7 GLY A  86
GLU A 121
ASP A 198
ASN A 205
 None
 0.72A 5n5dB-2qy6A:
12.0		 5n5dB-2qy6A:
25.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  90
LYS A 122
ASP A 176
ASP A 198
 None
 1.04A 5wz1C-2qy6A:
2.0		 5wz1C-2qy6A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  90
LYS A 122
ASP A 176
ASP A 198
 None
 1.05A 5wz1D-2qy6A:
5.5		 5wz1D-2qy6A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  90
LYS A 122
ASP A 176
ASP A 198
 None
 1.04A 5wz1E-2qy6A:
5.6		 5wz1E-2qy6A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  90
LYS A 122
ASP A 176
ASP A 198
 None
 1.04A 5wz1G-2qy6A:
5.5		 5wz1G-2qy6A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  90
LYS A 122
ASP A 176
ASP A 198
 None
 1.01A 5wz1H-2qy6A:
3.3		 5wz1H-2qy6A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  88
LYS A 122
ASP A 176
ASP A 198
 None
 0.80A 5wz2A-2qy6A:
4.3		 5wz2A-2qy6A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		5 / 12 GLY A  86
GLY A  88
LYS A 122
ASP A 176
ASP A 198
 None
 0.76A 5wz2B-2qy6A:
4.0		 5wz2B-2qy6A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2qy6 UPF0209 PROTEIN YFCK
(Escherichia
coli) 		6 / 10 VAL A  82
ALA A 194
LEU A 115
LEU A  63
THR A 226
LEU A  96
 None
 1.39A 6f5uA-2qy6A:
undetectable
6f5uB-2qy6A:
undetectable		 6f5uA-2qy6A:
15.96
6f5uB-2qy6A:
18.71