SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qyb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 2qyb MEMBRANE PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		3 / 3 LYS A  93
PRO A  94
LEU A  95
 None
 0.78A 3tpxE-2qybA:
undetectable		 3tpxE-2qybA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 2qyb MEMBRANE PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		5 / 12 TYR A  52
ILE A  38
VAL A  37
SER A 125
ILE A  73
 None
 1.10A 3vrjA-2qybA:
undetectable
3vrjC-2qybA:
undetectable		 3vrjA-2qybA:
20.58
3vrjC-2qybA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 2qyb MEMBRANE PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		5 / 11 ILE A  38
ILE A 113
GLY A 122
PHE A 121
ARG A  12
 None
 1.11A 4ac9B-2qybA:
undetectable
4ac9C-2qybA:
undetectable		 4ac9B-2qybA:
17.45
4ac9C-2qybA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 2qyb MEMBRANE PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		4 / 7 ILE A  38
LEU A  23
ALA A 147
ILE A 113
 None
 0.85A 4y03A-2qybA:
undetectable		 4y03A-2qybA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 2qyb MEMBRANE PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		4 / 4 LEU A 124
MET A  20
ILE A  73
LEU A  40
 None
 1.17A 5nfpA-2qybA:
undetectable		 5nfpA-2qybA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 2qyb MEMBRANE PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		5 / 10 TYR A  52
ILE A  38
VAL A  37
SER A 125
ILE A  73
 None
 1.11A 5u98A-2qybA:
undetectable		 5u98A-2qybA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 2qyb MEMBRANE PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		5 / 10 TYR A  52
ILE A  38
VAL A  37
SER A 125
ILE A  73
 None
 1.10A 5u98D-2qybA:
undetectable		 5u98D-2qybA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 2qyb MEMBRANE PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		4 / 8 LEU A 134
VAL A 126
LEU A 142
ILE A 111
 None
 0.99A 5v0vA-2qybA:
undetectable		 5v0vA-2qybA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 2qyb MEMBRANE PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		3 / 3 TYR A  72
HIS A 110
PHE A 108
 None
 0.91A 6esmA-2qybA:
undetectable		 6esmA-2qybA:
18.95