SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qyf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2qyf MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		5 / 9 PHE B  60
GLY B 248
ARG B 249
ALA B 173
LEU B 172
 None
 1.27A 1jb0A-2qyfB:
undetectable		 1jb0A-2qyfB:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVU_A_PRLA196_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 2qyf MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		4 / 6 LEU B 135
GLU B 139
THR B 183
TYR B  91
 None
 1.27A 1qvuA-2qyfB:
undetectable		 1qvuA-2qyfB:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2qyf MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		5 / 9 PHE B  60
GLY B 248
ARG B 249
ALA B 173
LEU B 172
 None
 1.26A 3pcqA-2qyfB:
undetectable		 3pcqA-2qyfB:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 2qyf MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		3 / 3 ARG B 144
PRO B 228
PHE B 141
 None
 1.01A 3thrC-2qyfB:
undetectable		 3thrC-2qyfB:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 2qyf MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		4 / 8 LEU B 135
VAL B 134
VAL B 150
ILE B 152
 None
 0.86A 4l4cB-2qyfB:
undetectable		 4l4cB-2qyfB:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 2qyf MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		5 / 11 PHE B  60
GLY B 248
ARG B 249
ALA B 173
LEU B 172
 None
 1.22A 4l6v1-2qyfB:
undetectable
4l6v6-2qyfB:
undetectable		 4l6v1-2qyfB:
14.78
4l6v6-2qyfB:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2qyf MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		4 / 8 PHE B  60
ARG B 249
ALA B 173
LEU B 172
 None
 0.98A 4rkuA-2qyfB:
undetectable
4rkuJ-2qyfB:
undetectable		 4rkuA-2qyfB:
15.00
4rkuJ-2qyfB:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2qyf MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		4 / 7 PHE B  60
ARG B 249
ALA B 173
LEU B 172
 None
 0.96A 4xk8A-2qyfB:
undetectable		 4xk8A-2qyfB:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2qyf MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		4 / 8 PHE B  60
ARG B 249
ALA B 173
LEU B 172
 None
 0.97A 4xk8a-2qyfB:
undetectable		 4xk8a-2qyfB:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2qyf MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		5 / 9 PHE B  60
GLY B 248
ARG B 249
ALA B 173
LEU B 172
 None
 1.25A 5l8rA-2qyfB:
undetectable		 5l8rA-2qyfB:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2qyf MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		5 / 10 PHE B  60
GLY B 248
ARG B 249
ALA B 173
LEU B 172
 None
 1.24A 5zjiA-2qyfB:
undetectable
5zjiJ-2qyfB:
undetectable		 5zjiA-2qyfB:
17.27
5zjiJ-2qyfB:
11.34