SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qyg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IWI_A_CAMA418_0 (CYTOCHROME P450-CAM)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 8	PHE A 137 TYR A 141 VAL A 116 VAL A 306	None	0.97A	1iwiA-2qygA: undetectable	1iwiA-2qygA: 22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P7L_C_SAMC685_1 (S-ADENOSYLMETHIONINE SYNTHETASE)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 8	ALA A 258 ASP A 241 ILE A 239 ILE A 263	None	0.90A	1p7lD-2qygA: undetectable	1p7lD-2qygA: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P7L_C_SAMC885_0 (S-ADENOSYLMETHIONINE SYNTHETASE)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 8	ALA A 258 ASP A 241 ILE A 239 ILE A 263	None	0.88A	1p7lC-2qygA: undetectable	1p7lC-2qygA: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG9_A_SAMA385_1 (S-ADENOSYLMETHIONINE SYNTHETASE)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 8	ALA A 258 ASP A 241 ILE A 239 ILE A 263	None	0.93A	1rg9B-2qygA: undetectable	1rg9B-2qygA: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG9_B_SAMB485_0 (S-ADENOSYLMETHIONINE SYNTHETASE)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 8	ALA A 258 ASP A 241 ILE A 239 ILE A 263	None	0.92A	1rg9A-2qygA: undetectable	1rg9A-2qygA: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG9_C_SAMC585_1 (S-ADENOSYLMETHIONINE SYNTHETASE)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 8	ALA A 258 ASP A 241 ILE A 239 ILE A 263	None	0.92A	1rg9D-2qygA: undetectable	1rg9D-2qygA: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG9_C_SAMC685_0 (S-ADENOSYLMETHIONINE SYNTHETASE)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 8	ALA A 258 ASP A 241 ILE A 239 ILE A 263	None	0.90A	1rg9C-2qygA: undetectable	1rg9C-2qygA: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SV9_A_DIFA701_1 (PHOSPHOLIPASE A2)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 8	LEU A 270 ALA A 286 ILE A 263 GLY A 315 CYH A 352	None	1.39A	1sv9A-2qygA: undetectable	1sv9A-2qygA: 11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V8B_A_ADNA502_2 (ADENOSYLHOMOCYSTEINA SE)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	3 / 3	GLU A 242 GLU A 248 LEU A 276	None	0.68A	1v8bA-2qygA: undetectable	1v8bA-2qygA: 22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVV_A_MK1A901_2 (POL POLYPROTEIN)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	3 / 3	ASP A 376 VAL A 318 PRO A 283	None	0.77A	2avvA-2qygA: undetectable	2avvA-2qygA: 14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2B17_A_DIFA701_1 (PHOSPHOLIPASE A2 VRV-PL-VIIIA)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 10	LEU A 270 ALA A 286 ILE A 263 GLY A 315 CYH A 352	None	1.40A	2b17A-2qygA: undetectable	2b17A-2qygA: 11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H77_A_T3A1_1 (THRA PROTEIN)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 12	ILE A 98 ALA A 65 ALA A 115 SER A 46 LEU A 132	None	1.14A	2h77A-2qygA: undetectable	2h77A-2qygA: 19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JC9_A_ADNA1497_1 (CYTOSOLIC PURINE 5'-NUCLEOTIDASE)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 7	ARG A 156 ASP A 163 ILE A 166 PHE A 377	None	1.27A	2jc9A-2qygA: undetectable	2jc9A-2qygA: 24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NMZ_B_ROCB401_3 (PROTEASE)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 12	GLY A 169 ASP A 360 GLY A 378 ILE A 166 ILE A 399	None	0.85A	2nmzB-2qygA: undetectable	2nmzB-2qygA: 14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEY_B_EV1B1771_1 (CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 8	LEU A 270 VAL A 319 ILE A 291 PHE A 294	None	0.96A	2weyB-2qygA: undetectable	2weyB-2qygA: 21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2N_C_X2NC1479_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 12	TYR A 235 VAL A 282 ALA A 216 ALA A 212 LEU A 249	None	1.34A	2x2nC-2qygA: undetectable	2x2nC-2qygA: 24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y00_A_Y00A601_1 (BETA-1 ADRENERGIC RECEPTOR)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 12	LEU A 249 VAL A 252 ASP A 199 PHE A 182 TYR A 235	None	1.48A	2y00A-2qygA: undetectable	2y00A-2qygA: 21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y01_B_Y00B601_1 (BETA-1 ADRENERGIC RECEPTOR)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 12	LEU A 249 VAL A 252 ASP A 199 PHE A 182 TYR A 235	None	1.47A	2y01B-2qygA: undetectable	2y01B-2qygA: 21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3H0A_A_9RAA500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 12	ALA A 416 ALA A 417 ARG A 427 LEU A 426 ALA A 423	None	0.91A	3h0aA-2qygA: undetectable	3h0aA-2qygA: 17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP2_B_PNNB5002_0 (TRANSCRIPTIONAL REGULATOR TCAR)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 5	ASN A 256 ALA A 216 ALA A 215 ARG A 214	None	1.05A	3kp2B-2qygA: undetectable	3kp2B-2qygA: 14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NXU_B_RITB600_1 (CYTOCHROME P450 3A4)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 12	PHE A 316 THR A 308 ILE A 239 ALA A 237 ILE A 196	None	1.12A	3nxuB-2qygA: undetectable	3nxuB-2qygA: 22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RV5_C_DXCC92_0 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 4	VAL A 368 PHE A 379 PHE A 168 VAL A 318	None	1.46A	3rv5C-2qygA: undetectable 3rv5D-2qygA: 0.0	3rv5C-2qygA: 13.24 3rv5D-2qygA: 13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9H_B_NCAB1164_0 (TANKYRASE-2)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 8	GLY A 219 TYR A 187 ALA A 183 GLU A 184	None	0.90A	3u9hB-2qygA: undetectable	3u9hB-2qygA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VW1_D_CVID301_1 (PUTATIVE REGULATORY PROTEIN)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	3 / 3	TYR A 141 MET A 307 LEU A 113	None	1.02A	3vw1D-2qygA: undetectable	3vw1D-2qygA: 17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AC9_C_DXCC1475_0 (MJ0495-LIKE PROTEIN)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 8	ILE A 234 ILE A 196 VAL A 318 GLY A 378	None	0.83A	4ac9C-2qygA: undetectable	4ac9C-2qygA: 23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACB_C_DXCC1475_0 (TRANSLATION ELONGATION FACTOR SELB)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 8	ILE A 234 ILE A 196 VAL A 318 GLY A 378	None	0.83A	4acbC-2qygA: undetectable	4acbC-2qygA: 23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DXU_A_ACAA711_1 (LACTOTRANSFERRIN)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 6	GLY A 395 VAL A 385 PRO A 392 GLY A 186	None	0.89A	4dxuA-2qygA: undetectable	4dxuA-2qygA: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HDL_A_DXCA75_0 (PPCA)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 8	ILE A 135 ILE A 109 PHE A 105 GLY A 103	None	0.93A	4hdlA-2qygA: undetectable	4hdlA-2qygA: 9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCN_A_MTLA804_0 (NITRIC OXIDE SYNTHASE, BRAIN)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 6	ARG A 305 ARG A 95 ASP A 25 ASP A 27	None	1.01A	4kcnA-2qygA: undetectable	4kcnA-2qygA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCN_B_MTLB805_0 (NITRIC OXIDE SYNTHASE, BRAIN)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 6	ARG A 305 ARG A 95 ASP A 25 ASP A 27	None	0.98A	4kcnB-2qygA: undetectable	4kcnB-2qygA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCN_B_MTLB805_0 (NITRIC OXIDE SYNTHASE, BRAIN)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 6	GLU A 69 ARG A 95 ASP A 25 ASP A 27	None	1.40A	4kcnB-2qygA: undetectable	4kcnB-2qygA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LNW_A_T3A501_1 (THYROID HORMONE RECEPTOR ALPHA)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 12	ILE A 98 ALA A 65 ALA A 115 SER A 46 LEU A 132	None	1.15A	4lnwA-2qygA: undetectable	4lnwA-2qygA: 19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LNX_A_T3A502_1 (THYROID HORMONE RECEPTOR ALPHA)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 12	ILE A 98 ALA A 65 ALA A 115 SER A 46 LEU A 132	None	1.15A	4lnxA-2qygA: undetectable	4lnxA-2qygA: 19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M11_C_MXMC606_1 (PROSTAGLANDIN G/H SYNTHASE 2)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 12	ILE A 166 VAL A 155 LEU A 159 VAL A 282 ALA A 260	None	1.25A	4m11C-2qygA: undetectable	4m11C-2qygA: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M11_D_MXMD606_1 (PROSTAGLANDIN G/H SYNTHASE 2)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 12	ILE A 166 VAL A 155 LEU A 159 VAL A 282 ALA A 260	None	1.25A	4m11D-2qygA: undetectable	4m11D-2qygA: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KPC_A_SAMA401_0 (PAVINE N-METHYLTRANSFERASE)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 12	GLY A 315 GLY A 147 VAL A 273 LEU A 284 ALA A 280	None	0.94A	5kpcA-2qygA: undetectable	5kpcA-2qygA: 21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MZJ_A_TEPA2401_1 (ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 8	LEU A 353 PHE A 168 LEU A 159 ILE A 234	None	0.97A	5mzjA-2qygA: undetectable	5mzjA-2qygA: 22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T8S_B_SAMB402_0 (S-ADENOSYLMETHIONINE SYNTHASE)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	4 / 8	ALA A 258 ASP A 241 ILE A 239 ILE A 263	None	0.90A	5t8sA-2qygA: undetectable	5t8sA-2qygA: 25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X24_A_LSNA502_1 (CYTOCHROME P450 2C9)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 12	ALA A 161 LEU A 159 VAL A 231 GLY A 193 LEU A 365	None	1.06A	5x24A-2qygA: undetectable	5x24A-2qygA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YF9_X_NIOX401_1 (CASEIN KINASE II SUBUNIT ALPHA')	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 9	LEU A 353 VAL A 318 VAL A 155 ILE A 234 ILE A 196	None	1.04A	5yf9X-2qygA: undetectable	5yf9X-2qygA: 11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z6M_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 11	ILE A 22 LEU A 142 PHE A 137 LEU A 310 ILE A 135	None	0.95A	5z6mA-2qygA: undetectable	5z6mA-2qygA: 17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJZ_B_GMJB301_0 (SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 12	LEU A 310 ILE A 22 PHE A 26 HIS A 100 VAL A 121	None	1.28A	6djzB-2qygA: undetectable	6djzB-2qygA: 19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJZ_C_GMJC301_0 (SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 12	ALA A 314 LEU A 310 PHE A 26 HIS A 100 VAL A 121	None	1.17A	6djzC-2qygA: undetectable	6djzC-2qygA: 19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NQA_K_SAMK500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	2qyg	RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2 (Rhodopseudomonas palustris)	5 / 10	ASP A 360 GLY A 358 GLY A 325 VAL A 368 PHE A 288	None	1.00A	6nqaK-2qygA: undetectable	6nqaK-2qygA: 22.95

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IWI_A_CAMA418_0","CYTOCHROME P450-CAM","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"PHE A 137;TYR A 141;VAL A 116;VAL A 306","None","0.97A","1iwiA-2qygA:undetectable","1iwiA-2qygA:22.97"],["1P7L_C_SAMC685_1","S-ADENOSYLMETHIONINE SYNTHETASE","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"ALA A 258;ASP A 241;ILE A 239;ILE A 263","None","0.90A","1p7lD-2qygA:undetectable","1p7lD-2qygA:22.70"],["1P7L_C_SAMC885_0","S-ADENOSYLMETHIONINE SYNTHETASE","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"ALA A 258;ASP A 241;ILE A 239;ILE A 263","None","0.88A","1p7lC-2qygA:undetectable","1p7lC-2qygA:22.70"],["1RG9_A_SAMA385_1","S-ADENOSYLMETHIONINE SYNTHETASE","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"ALA A 258;ASP A 241;ILE A 239;ILE A 263","None","0.93A","1rg9B-2qygA:undetectable","1rg9B-2qygA:22.70"],["1RG9_B_SAMB485_0","S-ADENOSYLMETHIONINE SYNTHETASE","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"ALA A 258;ASP A 241;ILE A 239;ILE A 263","None","0.92A","1rg9A-2qygA:undetectable","1rg9A-2qygA:22.70"],["1RG9_C_SAMC585_1","S-ADENOSYLMETHIONINE SYNTHETASE","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"ALA A 258;ASP A 241;ILE A 239;ILE A 263","None","0.92A","1rg9D-2qygA:undetectable","1rg9D-2qygA:22.70"],["1RG9_C_SAMC685_0","S-ADENOSYLMETHIONINE SYNTHETASE","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"ALA A 258;ASP A 241;ILE A 239;ILE A 263","None","0.90A","1rg9C-2qygA:undetectable","1rg9C-2qygA:22.70"],["1SV9_A_DIFA701_1","PHOSPHOLIPASE A2","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"LEU A 270;ALA A 286;ILE A 263;GLY A 315;CYH A 352","None","1.39A","1sv9A-2qygA:undetectable","1sv9A-2qygA:11.54"],["1V8B_A_ADNA502_2","ADENOSYLHOMOCYSTEINASE","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",3,"GLU A 242;GLU A 248;LEU A 276","None","0.68A","1v8bA-2qygA:undetectable","1v8bA-2qygA:22.12"],["2AVV_A_MK1A901_2","POL POLYPROTEIN","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",3,"ASP A 376;VAL A 318;PRO A 283","None","0.77A","2avvA-2qygA:undetectable","2avvA-2qygA:14.14"],["2B17_A_DIFA701_1","PHOSPHOLIPASE A2 VRV-PL-VIIIA","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"LEU A 270;ALA A 286;ILE A 263;GLY A 315;CYH A 352","None","1.40A","2b17A-2qygA:undetectable","2b17A-2qygA:11.54"],["2H77_A_T3A1_1","THRA PROTEIN","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"ILE A  98;ALA A  65;ALA A 115;SER A  46;LEU A 132","None","1.14A","2h77A-2qygA:undetectable","2h77A-2qygA:19.04"],["2JC9_A_ADNA1497_1","CYTOSOLIC PURINE 5'-NUCLEOTIDASE","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"ARG A 156;ASP A 163;ILE A 166;PHE A 377","None","1.27A","2jc9A-2qygA:undetectable","2jc9A-2qygA:24.05"],["2NMZ_B_ROCB401_3","PROTEASE","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"GLY A 169;ASP A 360;GLY A 378;ILE A 166;ILE A 399","None","0.85A","2nmzB-2qygA:undetectable","2nmzB-2qygA:14.14"],["2WEY_B_EV1B1771_1","CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"LEU A 270;VAL A 319;ILE A 291;PHE A 294","None","0.96A","2weyB-2qygA:undetectable","2weyB-2qygA:21.27"],["2X2N_C_X2NC1479_1","LANOSTEROL 14-ALPHA-DEMETHYLASE","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"TYR A 235;VAL A 282;ALA A 216;ALA A 212;LEU A 249","None","1.34A","2x2nC-2qygA:undetectable","2x2nC-2qygA:24.61"],["2Y00_A_Y00A601_1","BETA-1 ADRENERGIC RECEPTOR","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"LEU A 249;VAL A 252;ASP A 199;PHE A 182;TYR A 235","None","1.48A","2y00A-2qygA:undetectable","2y00A-2qygA:21.71"],["2Y01_B_Y00B601_1","BETA-1 ADRENERGIC RECEPTOR","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"LEU A 249;VAL A 252;ASP A 199;PHE A 182;TYR A 235","None","1.47A","2y01B-2qygA:undetectable","2y01B-2qygA:21.71"],["3H0A_A_9RAA500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"ALA A 416;ALA A 417;ARG A 427;LEU A 426;ALA A 423","None","0.91A","3h0aA-2qygA:undetectable","3h0aA-2qygA:17.66"],["3KP2_B_PNNB5002_0","TRANSCRIPTIONAL REGULATOR TCAR","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"ASN A 256;ALA A 216;ALA A 215;ARG A 214","None","1.05A","3kp2B-2qygA:undetectable","3kp2B-2qygA:14.71"],["3NXU_B_RITB600_1","CYTOCHROME P450 3A4","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"PHE A 316;THR A 308;ILE A 239;ALA A 237;ILE A 196","None","1.12A","3nxuB-2qygA:undetectable","3nxuB-2qygA:22.43"],["3RV5_C_DXCC92_0","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"VAL A 368;PHE A 379;PHE A 168;VAL A 318","None","1.46A","3rv5C-2qygA:undetectable;3rv5D-2qygA:0.0","3rv5C-2qygA:13.24;3rv5D-2qygA:13.24"],["3U9H_B_NCAB1164_0","TANKYRASE-2","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"GLY A 219;TYR A 187;ALA A 183;GLU A 184","None","0.90A","3u9hB-2qygA:undetectable","3u9hB-2qygA:20.00"],["3VW1_D_CVID301_1","PUTATIVE REGULATORY PROTEIN","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",3,"TYR A 141;MET A 307;LEU A 113","None","1.02A","3vw1D-2qygA:undetectable","3vw1D-2qygA:17.70"],["4AC9_C_DXCC1475_0","MJ0495-LIKE PROTEIN","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"ILE A 234;ILE A 196;VAL A 318;GLY A 378","None","0.83A","4ac9C-2qygA:undetectable","4ac9C-2qygA:23.62"],["4ACB_C_DXCC1475_0","TRANSLATION ELONGATION FACTOR SELB","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"ILE A 234;ILE A 196;VAL A 318;GLY A 378","None","0.83A","4acbC-2qygA:undetectable","4acbC-2qygA:23.62"],["4DXU_A_ACAA711_1","LACTOTRANSFERRIN","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"GLY A 395;VAL A 385;PRO A 392;GLY A 186","None","0.89A","4dxuA-2qygA:undetectable","4dxuA-2qygA:21.99"],["4HDL_A_DXCA75_0","PPCA","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"ILE A 135;ILE A 109;PHE A 105;GLY A 103","None","0.93A","4hdlA-2qygA:undetectable","4hdlA-2qygA:9.07"],["4KCN_A_MTLA804_0","NITRIC OXIDE SYNTHASE, BRAIN","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"ARG A 305;ARG A  95;ASP A  25;ASP A  27","None","1.01A","4kcnA-2qygA:undetectable","4kcnA-2qygA:21.15"],["4KCN_B_MTLB805_0","NITRIC OXIDE SYNTHASE, BRAIN","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"ARG A 305;ARG A  95;ASP A  25;ASP A  27","None","0.98A","4kcnB-2qygA:undetectable","4kcnB-2qygA:21.15"],["4KCN_B_MTLB805_0","NITRIC OXIDE SYNTHASE, BRAIN","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"GLU A  69;ARG A  95;ASP A  25;ASP A  27","None","1.40A","4kcnB-2qygA:undetectable","4kcnB-2qygA:21.15"],["4LNW_A_T3A501_1","THYROID HORMONE RECEPTOR ALPHA","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"ILE A  98;ALA A  65;ALA A 115;SER A  46;LEU A 132","None","1.15A","4lnwA-2qygA:undetectable","4lnwA-2qygA:19.30"],["4LNX_A_T3A502_1","THYROID HORMONE RECEPTOR ALPHA","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"ILE A  98;ALA A  65;ALA A 115;SER A  46;LEU A 132","None","1.15A","4lnxA-2qygA:undetectable","4lnxA-2qygA:19.30"],["4M11_C_MXMC606_1","PROSTAGLANDIN G\/H SYNTHASE 2","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"ILE A 166;VAL A 155;LEU A 159;VAL A 282;ALA A 260","None","1.25A","4m11C-2qygA:undetectable","4m11C-2qygA:21.66"],["4M11_D_MXMD606_1","PROSTAGLANDIN G\/H SYNTHASE 2","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"ILE A 166;VAL A 155;LEU A 159;VAL A 282;ALA A 260","None","1.25A","4m11D-2qygA:undetectable","4m11D-2qygA:21.66"],["5KPC_A_SAMA401_0","PAVINE N-METHYLTRANSFERASE","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"GLY A 315;GLY A 147;VAL A 273;LEU A 284;ALA A 280","None","0.94A","5kpcA-2qygA:undetectable","5kpcA-2qygA:21.40"],["5MZJ_A_TEPA2401_1","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"LEU A 353;PHE A 168;LEU A 159;ILE A 234","None","0.97A","5mzjA-2qygA:undetectable","5mzjA-2qygA:22.02"],["5T8S_B_SAMB402_0","S-ADENOSYLMETHIONINE SYNTHASE","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",4,"ALA A 258;ASP A 241;ILE A 239;ILE A 263","None","0.90A","5t8sA-2qygA:undetectable","5t8sA-2qygA:25.85"],["5X24_A_LSNA502_1","CYTOCHROME P450 2C9","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"ALA A 161;LEU A 159;VAL A 231;GLY A 193;LEU A 365","None","1.06A","5x24A-2qygA:undetectable","5x24A-2qygA:21.43"],["5YF9_X_NIOX401_1","CASEIN KINASE II SUBUNIT ALPHA'","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"LEU A 353;VAL A 318;VAL A 155;ILE A 234;ILE A 196","None","1.04A","5yf9X-2qygA:undetectable","5yf9X-2qygA:11.51"],["5Z6M_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"ILE A  22;LEU A 142;PHE A 137;LEU A 310;ILE A 135","None","0.95A","5z6mA-2qygA:undetectable","5z6mA-2qygA:17.24"],["6DJZ_B_GMJB301_0","SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"LEU A 310;ILE A  22;PHE A  26;HIS A 100;VAL A 121","None","1.28A","6djzB-2qygA:undetectable","6djzB-2qygA:19.60"],["6DJZ_C_GMJC301_0","SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"ALA A 314;LEU A 310;PHE A  26;HIS A 100;VAL A 121","None","1.17A","6djzC-2qygA:undetectable","6djzC-2qygA:19.60"],["6NQA_K_SAMK500_0","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","2qyg","RIBULOSE BISPHOSPHATE CARBOXYLASE-LIKE PROTEIN 2","Rhodopseudomonas palustris",5,"ASP A 360;GLY A 358;GLY A 325;VAL A 368;PHE A 288","None","1.00A","6nqaK-2qygA:undetectable","6nqaK-2qygA:22.95"]]