SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qyz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 2qyz UNCHARACTERIZED
PROTEIN
(Clostridium
tetani) 		3 / 3 ARG A  10
GLY A 120
ASP A  70
 None
 0.56A 1kf6A-2qyzA:
undetectable
1kf6B-2qyzA:
undetectable		 1kf6A-2qyzA:
12.16
1kf6B-2qyzA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 2qyz UNCHARACTERIZED
PROTEIN
(Clostridium
tetani) 		5 / 12 VAL A  20
GLN A  25
ILE A  42
ALA A  11
PHE A  52
 None
 1.11A 2qb4A-2qyzA:
undetectable		 2qb4A-2qyzA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2qyz UNCHARACTERIZED
PROTEIN
(Clostridium
tetani) 		4 / 8 GLU A  63
LYS A  64
ASN A  62
ILE A  66
 None
 1.33A 3kp6A-2qyzA:
undetectable
3kp6B-2qyzA:
undetectable		 3kp6A-2qyzA:
24.20
3kp6B-2qyzA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 2qyz UNCHARACTERIZED
PROTEIN
(Clostridium
tetani) 		3 / 3 CYH A 116
ASN A  62
LYS A  73
 None
 1.46A 4k50A-2qyzA:
undetectable		 4k50A-2qyzA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 2qyz UNCHARACTERIZED
PROTEIN
(Clostridium
tetani) 		3 / 3 LYS A  64
ILE A  66
ILE A  84
 None
 0.73A 4y0qA-2qyzA:
undetectable		 4y0qA-2qyzA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2qyz UNCHARACTERIZED
PROTEIN
(Clostridium
tetani) 		4 / 7 ILE A  71
GLY A 120
CYH A  95
ASP A  60
 None
 0.94A 5hieA-2qyzA:
undetectable		 5hieA-2qyzA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2qyz UNCHARACTERIZED
PROTEIN
(Clostridium
tetani) 		4 / 8 ILE A  71
GLY A 120
CYH A  95
ASP A  60
 None
 0.88A 5hieD-2qyzA:
undetectable		 5hieD-2qyzA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 2qyz UNCHARACTERIZED
PROTEIN
(Clostridium
tetani) 		4 / 5 GLY A 120
ASN A 121
ASP A  70
ARG A  10
 None
 1.06A 6dwdB-2qyzA:
undetectable
6dwdD-2qyzA:
undetectable		 6dwdB-2qyzA:
11.75
6dwdD-2qyzA:
11.75