SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qz7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 2qz7 UNCHARACTERIZED
PROTEIN SCO6318
(Streptomyces
coelicolor) 		4 / 8 SER A 175
ALA A 181
ILE A 106
THR A  47
 None
 0.79A 3bpxA-2qz7A:
undetectable
3bpxB-2qz7A:
undetectable		 3bpxA-2qz7A:
22.34
3bpxB-2qz7A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 2qz7 UNCHARACTERIZED
PROTEIN SCO6318
(Streptomyces
coelicolor) 		5 / 9 PHE A 142
VAL A 145
GLY A 147
VAL A 153
GLY A 172
 None
 1.39A 3kmoA-2qz7A:
undetectable		 3kmoA-2qz7A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2qz7 UNCHARACTERIZED
PROTEIN SCO6318
(Streptomyces
coelicolor) 		3 / 3 ARG A 104
HIS A  55
TYR A  49
 None
 1.32A 4fu8A-2qz7A:
undetectable		 4fu8A-2qz7A:
18.18