SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qza'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 11 LEU A 273
ALA A 299
ILE A 360
THR A 293
ILE A 295
 None
 0.94A 1c6yA-2qzaA:
undetectable		 1c6yA-2qzaA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBK_A_RAPA225_1
(FKBP25)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 626
ILE A 612
ALA A 671
ILE A 668
PHE A 693
 None
 0.96A 1pbkA-2qzaA:
undetectable		 1pbkA-2qzaA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDK_A_C2FA1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 11 TYR A 444
LEU A 450
HIS A 477
TYR A 445
HIS A 405
 None
 1.47A 2idkA-2qzaA:
0.0
2idkB-2qzaA:
0.0
2idkC-2qzaA:
0.0
2idkD-2qzaA:
0.0		 2idkA-2qzaA:
18.53
2idkB-2qzaA:
18.53
2idkC-2qzaA:
18.53
2idkD-2qzaA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		4 / 5 LEU A 689
ALA A 692
TRP A 781
LEU A 777
 None
 1.11A 2oaxA-2qzaA:
undetectable		 2oaxA-2qzaA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		4 / 8 ILE A 609
LEU A 689
PHE A 693
PHE A 651
 None
 0.84A 2vctA-2qzaA:
1.6		 2vctA-2qzaA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		4 / 8 ILE A 609
LEU A 689
PHE A 693
PHE A 651
 None
 0.85A 2vctB-2qzaA:
2.8		 2vctB-2qzaA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		4 / 8 ILE A 609
LEU A 689
PHE A 693
PHE A 651
 None
 0.88A 2vctC-2qzaA:
1.6		 2vctC-2qzaA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		4 / 7 LEU A 686
LEU A 719
LEU A 726
GLU A 725
 None
 0.96A 2vq5B-2qzaA:
undetectable		 2vq5B-2qzaA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 GLN A 282
PHE A 345
THR A 359
ASN A 351
GLY A 353
 None
 1.46A 3aodC-2qzaA:
undetectable		 3aodC-2qzaA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		3 / 3 THR A 541
SER A 535
PHE A 565
 None
 0.66A 3d4sA-2qzaA:
2.8		 3d4sA-2qzaA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		4 / 5 LEU A 331
LYS A 371
GLN A 373
LEU A 326
 None
 0.94A 3h5gA-2qzaA:
undetectable
3h5gB-2qzaA:
undetectable		 3h5gA-2qzaA:
4.12
3h5gB-2qzaA:
4.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_J_CU9J301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 11 LYS A 354
GLN A 281
ILE A 639
SER A 239
SER A 259
 None
 1.34A 3peoI-2qzaA:
0.0
3peoJ-2qzaA:
0.0		 3peoI-2qzaA:
17.36
3peoJ-2qzaA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		3 / 3 HIS A 633
SER A 755
ASN A 347
 None
 0.87A 3s8pB-2qzaA:
undetectable		 3s8pB-2qzaA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 10 PHE A 243
PHE A 197
ALA A 200
ILE A 205
PHE A 207
 None
 1.36A 3t3qA-2qzaA:
undetectable		 3t3qA-2qzaA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 10 PHE A 243
PHE A 197
ALA A 200
ILE A 205
PHE A 207
 None
 1.31A 3t3qB-2qzaA:
undetectable		 3t3qB-2qzaA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 10 PHE A 243
PHE A 197
ALA A 200
ILE A 205
PHE A 207
 None
 1.31A 3t3qC-2qzaA:
undetectable		 3t3qC-2qzaA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 10 PHE A 243
PHE A 197
ALA A 200
ILE A 205
PHE A 207
 None
 1.29A 3t3qD-2qzaA:
undetectable		 3t3qD-2qzaA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		4 / 6 GLU A 396
HIS A 467
VAL A 474
PHE A 425
 None
 1.12A 4a97E-2qzaA:
2.0		 4a97E-2qzaA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 545
ILE A 509
LEU A 500
HIS A 510
LEU A 513
 None
 1.19A 4j24D-2qzaA:
undetectable		 4j24D-2qzaA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		4 / 8 PRO A 283
VAL A 271
TYR A 275
LEU A 290
 None
 0.95A 4pwdA-2qzaA:
2.1		 4pwdA-2qzaA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 9 LEU A 346
LEU A 331
THR A 359
LEU A 357
ILE A 360
 None
 1.37A 4ubsA-2qzaA:
undetectable		 4ubsA-2qzaA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		3 / 3 SER A 236
ASP A 196
ASP A 201
 None
 0.78A 4uckA-2qzaA:
undetectable		 4uckA-2qzaA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		4 / 7 MET A 720
PHE A 687
SER A 690
ARG A 695
 None
 1.12A 4xk8A-2qzaA:
2.9		 4xk8A-2qzaA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 VAL A 402
LEU A 331
ILE A 356
LEU A 357
LEU A 301
 None
 1.11A 4y0qA-2qzaA:
undetectable		 4y0qA-2qzaA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		4 / 6 VAL A 395
LEU A 399
CYH A 391
LEU A 387
 None
 1.22A 5hrqB-2qzaA:
undetectable
5hrqI-2qzaA:
undetectable
5hrqJ-2qzaA:
undetectable		 5hrqB-2qzaA:
4.91
5hrqI-2qzaA:
3.38
5hrqJ-2qzaA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 273
LEU A 241
LEU A 253
ILE A 205
THR A 279
 None
 1.22A 5ienB-2qzaA:
undetectable		 5ienB-2qzaA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 253
PHE A 248
PHE A 233
THR A 261
LEU A 211
 None
 1.02A 5iepA-2qzaA:
undetectable		 5iepA-2qzaA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		4 / 6 VAL A 317
LEU A 253
SER A 254
ARG A 296
 None
 1.04A 5jw1A-2qzaA:
undetectable		 5jw1A-2qzaA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 MET A 761
GLN A 762
ALA A 758
LEU A 773
ILE A 776
 None
 1.50A 5vlmA-2qzaA:
undetectable		 5vlmA-2qzaA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 MET A 761
GLN A 762
ALA A 758
LEU A 777
ILE A 776
 None
 1.41A 5vlmA-2qzaA:
undetectable		 5vlmA-2qzaA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 MET A 761
GLN A 762
ALA A 758
LEU A 777
ILE A 776
 None
 1.32A 5vlmG-2qzaA:
1.4		 5vlmG-2qzaA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		3 / 3 LYS A 354
ASN A 352
SER A 699
 None
 1.25A 5yw0A-2qzaA:
undetectable		 5yw0A-2qzaA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 2qza SECRETED EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 ILE A 650
GLY A 714
ALA A 711
ALA A 716
ALA A 694
 None
 1.07A 5zw4A-2qzaA:
undetectable		 5zw4A-2qzaA:
17.31