SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qzb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 2qzb UNCHARACTERIZED
PROTEIN YFEY
(Escherichia
coli) 		3 / 3 GLN A 156
HIS A 157
ARG A 190
 None
 0.92A 1zlqA-2qzbA:
undetectable		 1zlqA-2qzbA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 2qzb UNCHARACTERIZED
PROTEIN YFEY
(Escherichia
coli) 		5 / 12 VAL A  96
ALA A  94
LEU A  64
LEU A  70
SER A  72
 None
 1.19A 3hj3C-2qzbA:
undetectable		 3hj3C-2qzbA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 2qzb UNCHARACTERIZED
PROTEIN YFEY
(Escherichia
coli) 		5 / 12 GLY A  99
GLY A 102
VAL A  82
ASN A  78
SER A 105
 None
 1.20A 4f84A-2qzbA:
undetectable		 4f84A-2qzbA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 2qzb UNCHARACTERIZED
PROTEIN YFEY
(Escherichia
coli) 		5 / 12 MET A  95
LEU A  55
ARG A  83
ILE A 107
LEU A  64
 None
 1.24A 4j26B-2qzbA:
undetectable		 4j26B-2qzbA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 2qzb UNCHARACTERIZED
PROTEIN YFEY
(Escherichia
coli) 		4 / 7 ILE A 158
ILE A 107
ILE A 114
LEU A  49
 None
 0.83A 5fukA-2qzbA:
undetectable
5fukB-2qzbA:
undetectable		 5fukA-2qzbA:
20.75
5fukB-2qzbA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 2qzb UNCHARACTERIZED
PROTEIN YFEY
(Escherichia
coli) 		4 / 8 ARG A  83
GLY A 102
GLN A  56
LEU A  55
 None
 1.00A 5sxtB-2qzbA:
undetectable		 5sxtB-2qzbA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 2qzb UNCHARACTERIZED
PROTEIN YFEY
(Escherichia
coli) 		4 / 8 VAL A  87
LYS A  89
ILE A 114
ASP A 113
 None
 0.58A 5y9mA-2qzbA:
undetectable		 5y9mA-2qzbA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 2qzb UNCHARACTERIZED
PROTEIN YFEY
(Escherichia
coli) 		4 / 8 VAL A  87
LYS A  89
ILE A 114
ASP A 113
 None
 0.60A 5y9mX-2qzbA:
undetectable		 5y9mX-2qzbA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 2qzb UNCHARACTERIZED
PROTEIN YFEY
(Escherichia
coli) 		4 / 7 VAL A  87
LYS A  89
ILE A 114
ASP A 113
 None
 0.62A 5yf9B-2qzbA:
undetectable		 5yf9B-2qzbA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 2qzb UNCHARACTERIZED
PROTEIN YFEY
(Escherichia
coli) 		4 / 7 VAL A  87
LYS A  89
ILE A 114
ASP A 113
 None
 0.74A 5ywmX-2qzbA:
undetectable		 5ywmX-2qzbA:
15.53