SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qzi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 2qzi UNCHARACTERIZED
PROTEIN
(Streptococcus
thermophilus) 		4 / 7 LYS A   2
ALA A  31
THR A  34
VAL A  36
 None
 1.02A 1dvxB-2qziA:
undetectable		 1dvxB-2qziA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 2qzi UNCHARACTERIZED
PROTEIN
(Streptococcus
thermophilus) 		5 / 9 ASP A  81
LEU A  79
ILE A  73
THR A  85
ILE A  94
 None
 1.43A 1hzeA-2qziA:
undetectable
1hzeB-2qziA:
undetectable		 1hzeA-2qziA:
21.49
1hzeB-2qziA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 2qzi UNCHARACTERIZED
PROTEIN
(Streptococcus
thermophilus) 		5 / 9 THR A  85
ILE A  94
ASP A  81
LEU A  79
ILE A  73
 None
 1.43A 1hzeA-2qziA:
undetectable
1hzeB-2qziA:
undetectable		 1hzeA-2qziA:
21.49
1hzeB-2qziA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE507_0
(NAD-DEPENDENT
DEACETYLASE 2)		 2qzi UNCHARACTERIZED
PROTEIN
(Streptococcus
thermophilus) 		4 / 7 ILE A  77
LEU A  79
ILE A  73
ASP A  74
 None
 0.94A 1yc2E-2qziA:
undetectable		 1yc2E-2qziA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 2qzi UNCHARACTERIZED
PROTEIN
(Streptococcus
thermophilus) 		4 / 7 LYS A   2
ALA A  31
THR A  34
VAL A  36
 None
 0.97A 3d2tA-2qziA:
undetectable		 3d2tA-2qziA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 2qzi UNCHARACTERIZED
PROTEIN
(Streptococcus
thermophilus) 		4 / 6 LYS A   2
ALA A  31
THR A  34
VAL A  36
 None
 0.99A 3d2tB-2qziA:
undetectable		 3d2tB-2qziA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2qzi UNCHARACTERIZED
PROTEIN
(Streptococcus
thermophilus) 		3 / 3 THR A  34
ASN A  33
GLU A  60
 None
 0.75A 3v4tA-2qziA:
undetectable
3v4tC-2qziA:
undetectable		 3v4tA-2qziA:
16.40
3v4tC-2qziA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 2qzi UNCHARACTERIZED
PROTEIN
(Streptococcus
thermophilus) 		4 / 7 LYS A   2
ALA A  31
THR A  34
VAL A  36
 None
 0.93A 4ik7A-2qziA:
undetectable		 4ik7A-2qziA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 2qzi UNCHARACTERIZED
PROTEIN
(Streptococcus
thermophilus) 		4 / 8 ILE A  73
THR A  85
VAL A  86
GLU A  93
 None
 1.16A 6fbvC-2qziA:
undetectable		 6fbvC-2qziA:
6.62