SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qzp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		5 / 12 TYR A 243
LEU A 311
SER A 269
VAL A 309
LEU A  27
 None
 1.36A 1db1A-2qzpA:
undetectable		 1db1A-2qzpA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 8 LEU A 177
ARG A 174
PHE A 170
GLY A 171
 None
 1.00A 1fapB-2qzpA:
undetectable		 1fapB-2qzpA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		5 / 11 LEU A 516
ALA A 464
MET A 442
ILE A 519
HIS A 549
 None
 1.14A 1g50A-2qzpA:
undetectable		 1g50A-2qzpA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		5 / 11 ASN A 487
ARG A 526
PHE A 485
GLY A 369
PHE A 488
 None
 1.32A 1ho5A-2qzpA:
undetectable		 1ho5A-2qzpA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 7 GLN A 282
SER A 375
SER A 301
ASN A 284
 None
 1.22A 1ig3A-2qzpA:
2.1
1ig3B-2qzpA:
2.2		 1ig3A-2qzpA:
19.74
1ig3B-2qzpA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 8 TYR A 444
LEU A 568
VAL A 392
VAL A 363
 None
 0.95A 1iwiA-2qzpA:
undetectable		 1iwiA-2qzpA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 6 PHE A 488
ASN A 487
ILE A 412
GLY A 173
 None
 1.09A 1oniD-2qzpA:
2.0
1oniF-2qzpA:
2.1		 1oniD-2qzpA:
15.31
1oniF-2qzpA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		5 / 10 LEU A 516
ALA A 464
MET A 442
ILE A 519
HIS A 549
 None
 1.09A 1pcgA-2qzpA:
undetectable		 1pcgA-2qzpA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		5 / 12 GLY A 369
HIS A 367
SER A 344
GLU A 419
PHE A 371
 None
 1.44A 1qu3A-2qzpA:
undetectable		 1qu3A-2qzpA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 7 ARG A 105
ASP A  69
GLY A 117
PHE A 126
 None
 0.85A 1rtsB-2qzpA:
undetectable		 1rtsB-2qzpA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 8 TYR A 444
LEU A 568
VAL A 392
VAL A 363
 None
 0.90A 1t86A-2qzpA:
undetectable		 1t86A-2qzpA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 8 TYR A  25
GLU A  23
VAL A  38
TYR A  49
 None
 1.18A 2fl5E-2qzpA:
undetectable
2fl5F-2qzpA:
undetectable		 2fl5E-2qzpA:
16.76
2fl5F-2qzpA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 7 TYR A 444
VAL A 572
VAL A 392
VAL A 363
 None
 0.94A 2qbnA-2qzpA:
undetectable		 2qbnA-2qzpA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		3 / 3 GLN A  28
THR A 297
TRP A 250
 None
 1.18A 2rctA-2qzpA:
undetectable		 2rctA-2qzpA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 6 TYR A 444
LEU A 568
VAL A 392
VAL A 363
 None
 0.93A 2z97A-2qzpA:
undetectable		 2z97A-2qzpA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSF_A_ACTA803_0
(PANTOTHENATE KINASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 4 ARG A 526
PRO A 521
GLY A 555
HIS A 556
 None
 1.46A 2zsfA-2qzpA:
1.6		 2zsfA-2qzpA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 8 TYR A 444
LEU A 568
VAL A 363
LEU A 365
 None
 0.81A 2zujA-2qzpA:
undetectable		 2zujA-2qzpA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 8 TYR A 444
LEU A 568
VAL A 392
VAL A 363
 None
 0.88A 2zujA-2qzpA:
undetectable		 2zujA-2qzpA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 6 VAL A 288
PHE A 272
ARG A 287
ARG A 160
 None
 0.95A 3bjwF-2qzpA:
undetectable		 3bjwF-2qzpA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 7 VAL A  67
ILE A 114
GLY A 128
LEU A 150
 None
 0.93A 3bjwF-2qzpA:
undetectable		 3bjwF-2qzpA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_1
(REPRESSOR PROTEIN
MPHR(A))		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 5 ASN A 284
ASN A 396
HIS A 367
ALA A 372
 None
 1.47A 3frqA-2qzpA:
0.9		 3frqA-2qzpA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		5 / 12 GLU A 490
ARG A 149
VAL A 471
PHE A 170
ILE A 489
 None
 1.22A 3k13C-2qzpA:
undetectable		 3k13C-2qzpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		3 / 3 ASP A 524
ARG A 526
ALA A 469
 None
 0.73A 3mbgC-2qzpA:
undetectable		 3mbgC-2qzpA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		5 / 12 LEU A 455
ALA A 467
GLY A 443
GLY A 465
ALA A 469
 None
 0.84A 3ou6A-2qzpA:
2.6		 3ou6A-2qzpA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		5 / 12 LEU A 455
ALA A 467
GLY A 443
GLY A 465
ALA A 469
 None
 0.84A 3ou6B-2qzpA:
2.7		 3ou6B-2qzpA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		5 / 12 LEU A 455
ALA A 467
GLY A 443
GLY A 465
ALA A 469
 None
 0.87A 3ou7B-2qzpA:
2.6		 3ou7B-2qzpA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		5 / 12 LEU A 516
ALA A 464
MET A 442
ILE A 519
HIS A 549
 None
 1.09A 3q95A-2qzpA:
undetectable		 3q95A-2qzpA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		5 / 12 LEU A 516
ALA A 464
MET A 442
ILE A 519
HIS A 549
 None
 1.09A 3q95B-2qzpA:
undetectable		 3q95B-2qzpA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 4 GLY A 468
GLY A 448
THR A 451
LEU A 516
 None
 0.93A 3si7C-2qzpA:
undetectable
3si7D-2qzpA:
undetectable		 3si7C-2qzpA:
20.36
3si7D-2qzpA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		5 / 12 VAL A  74
LEU A  37
ILE A  78
VAL A  67
LEU A  79
 None
 1.20A 3w67D-2qzpA:
3.0		 3w67D-2qzpA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 7 TYR A 444
LEU A 568
VAL A 392
VAL A 363
 None
 0.96A 4cp4A-2qzpA:
undetectable		 4cp4A-2qzpA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 7 PHE A 488
PHE A 371
GLY A 172
ILE A 411
 None
 0.73A 4ejjA-2qzpA:
undetectable		 4ejjA-2qzpA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 7 MET A 450
ILE A 411
ARG A 398
VAL A 346
 None
 1.44A 4f4dA-2qzpA:
2.6		 4f4dA-2qzpA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		5 / 11 TRP A 474
LEU A 492
LEU A 420
GLY A 417
TYR A 397
 None
 1.45A 4foxC-2qzpA:
undetectable		 4foxC-2qzpA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 6 LEU A 518
ILE A 512
THR A 451
GLY A 465
 None
 1.03A 4l39A-2qzpA:
undetectable		 4l39A-2qzpA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 8 TYR A 444
LEU A 568
VAL A 392
VAL A 363
 None
 0.91A 4l4bA-2qzpA:
undetectable		 4l4bA-2qzpA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 6 MET A 450
ILE A 411
ARG A 398
VAL A 346
 None
 1.37A 4mk4B-2qzpA:
3.6		 4mk4B-2qzpA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		5 / 12 ILE A  78
ALA A 138
LEU A 139
LEU A  92
LEU A 106
 None
 0.92A 4o1zA-2qzpA:
undetectable		 4o1zA-2qzpA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		3 / 3 MET A 477
MET A 536
TYR A 449
 None
 1.18A 4p6xI-2qzpA:
undetectable		 4p6xI-2qzpA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 7 GLU A 514
LEU A 516
LEU A 539
LEU A 535
 None
 0.77A 4wg0B-2qzpA:
undetectable
4wg0C-2qzpA:
undetectable		 4wg0B-2qzpA:
5.00
4wg0C-2qzpA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 7 LEU A 539
LEU A 535
GLU A 514
LEU A 516
 None
 0.74A 4wg0L-2qzpA:
undetectable
4wg0M-2qzpA:
undetectable		 4wg0L-2qzpA:
5.00
4wg0M-2qzpA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 6 PRO A 370
ILE A 412
VAL A 175
THR A 401
 None
 0.94A 4xe5A-2qzpA:
2.0		 4xe5A-2qzpA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 6 GLU A 217
ASP A 422
ARG A 398
GLY A 399
 None
 0.76A 5cdnC-2qzpA:
undetectable
5cdnD-2qzpA:
3.6		 5cdnC-2qzpA:
23.19
5cdnD-2qzpA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 6 GLU A 217
ASP A 422
ARG A 398
GLY A 399
 None
 0.80A 5cdnT-2qzpA:
undetectable
5cdnU-2qzpA:
3.3		 5cdnT-2qzpA:
23.19
5cdnU-2qzpA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		5 / 9 LEU A 575
VAL A 466
GLY A 465
THR A 451
VAL A 366
 None
 1.30A 5cp4A-2qzpA:
undetectable		 5cp4A-2qzpA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 4 LEU A 516
ILE A 512
PRO A 505
LEU A 535
 None
 1.05A 5eb3A-2qzpA:
undetectable		 5eb3A-2qzpA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_C_ACTC1403_0
(L-THREONINE
3-DEHYDROGENASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 4 MET A 561
SER A  45
VAL A  46
GLY A  40
 None
 1.29A 5k50C-2qzpA:
0.9		 5k50C-2qzpA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		3 / 3 SER A 433
ALA A 430
THR A 362
 None
 0.71A 5n0xB-2qzpA:
2.2		 5n0xB-2qzpA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		3 / 3 LEU A 461
VAL A 423
ASP A 422
 None
 0.50A 5x23A-2qzpA:
undetectable		 5x23A-2qzpA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 8 ILE A 159
PHE A 126
ALA A 148
LEU A 150
 None
 0.72A 5y7pE-2qzpA:
undetectable		 5y7pE-2qzpA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 2qzp ACYLAMINO-ACID-RELEA
SING ENZYME
(Aeropyrum
pernix) 		4 / 4 VAL A 156
GLY A 117
ASP A  69
ASP A 119
 None
 1.18A 6cjkC-2qzpA:
undetectable		 6cjkC-2qzpA:
16.43