SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qzq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1G_B_MTXB171_1
(DIHYDROFOLATE
REDUCTASE)		 2qzq AXIN INTERACTOR,
DORSALIZATION
ASSOCIATED PROTEIN
(Danio
rerio) 		5 / 12 VAL A  56
GLU A 130
ILE A 131
LEU A  34
ILE A 104
 None
 1.05A 1d1gB-2qzqA:
undetectable		 1d1gB-2qzqA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 2qzq AXIN INTERACTOR,
DORSALIZATION
ASSOCIATED PROTEIN
(Danio
rerio) 		5 / 12 LEU A  25
LEU A  33
VAL A  58
LEU A  98
LEU A  95
 None
 1.08A 1sn5B-2qzqA:
2.9
1sn5D-2qzqA:
2.7		 1sn5B-2qzqA:
18.18
1sn5D-2qzqA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 2qzq AXIN INTERACTOR,
DORSALIZATION
ASSOCIATED PROTEIN
(Danio
rerio) 		5 / 12 LEU A  98
LEU A  95
LEU A  25
LEU A  33
VAL A  58
 None
 1.09A 1sn5B-2qzqA:
2.9
1sn5D-2qzqA:
2.7		 1sn5B-2qzqA:
18.18
1sn5D-2qzqA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 2qzq AXIN INTERACTOR,
DORSALIZATION
ASSOCIATED PROTEIN
(Danio
rerio) 		4 / 7 GLN A 166
LEU A 168
LEU A  95
LEU A  34
 None
 0.71A 3bgdB-2qzqA:
undetectable		 3bgdB-2qzqA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 2qzq AXIN INTERACTOR,
DORSALIZATION
ASSOCIATED PROTEIN
(Danio
rerio) 		3 / 3 LYS A 142
LYS A 143
PRO A 144
 None
 1.26A 4dv1L-2qzqA:
undetectable		 4dv1L-2qzqA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_A_198A601_1
(SERUM ALBUMIN)		 2qzq AXIN INTERACTOR,
DORSALIZATION
ASSOCIATED PROTEIN
(Danio
rerio) 		5 / 10 LEU A 168
MET A 126
ALA A 103
PHE A 106
LEU A 164
 None
 1.27A 4la0A-2qzqA:
undetectable		 4la0A-2qzqA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_B_198B601_1
(SERUM ALBUMIN)		 2qzq AXIN INTERACTOR,
DORSALIZATION
ASSOCIATED PROTEIN
(Danio
rerio) 		5 / 9 LEU A 168
MET A 126
ALA A 103
PHE A 106
LEU A 164
 None
 1.35A 4la0B-2qzqA:
undetectable		 4la0B-2qzqA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 2qzq AXIN INTERACTOR,
DORSALIZATION
ASSOCIATED PROTEIN
(Danio
rerio) 		5 / 12 LEU A  66
ALA A 103
ILE A  64
ASP A 146
LEU A  61
 None
 1.22A 5nfjC-2qzqA:
undetectable		 5nfjC-2qzqA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 2qzq AXIN INTERACTOR,
DORSALIZATION
ASSOCIATED PROTEIN
(Danio
rerio) 		5 / 12 LEU A  98
LEU A  66
ILE A 104
ALA A 103
GLU A 127
 None
 1.13A 5v0vA-2qzqA:
undetectable		 5v0vA-2qzqA:
13.71