SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qzu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 8 ILE A  33
HIS A  55
LEU A  59
VAL A 308
 None
 0.88A 1fslA-2qzuA:
undetectable		 1fslA-2qzuA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 8 ILE A  33
HIS A  55
LEU A  59
VAL A 308
 None
 0.90A 1fslB-2qzuA:
undetectable		 1fslB-2qzuA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JQD_A_HSMA600_1
(HISTAMINE
N-METHYLTRANSFERASE)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 7 GLU A 101
VAL A 152
TRP A 154
ASN A  99
 None
 1.41A 1jqdA-2qzuA:
undetectable		 1jqdA-2qzuA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 12 PRO A 343
LEU A 340
LEU A  59
ILE A 346
SER A  61
 None
 1.43A 1lbcA-2qzuA:
undetectable
1lbcC-2qzuA:
undetectable		 1lbcA-2qzuA:
18.95
1lbcC-2qzuA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 12 ILE A 346
SER A  61
PRO A 343
LEU A 340
LEU A  59
 None
 1.40A 1lbcA-2qzuA:
undetectable
1lbcC-2qzuA:
undetectable		 1lbcA-2qzuA:
18.95
1lbcC-2qzuA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 12 LEU A  83
GLY A  86
VAL A 379
LEU A 365
LEU A 120
 None
 1.33A 1nhzA-2qzuA:
undetectable		 1nhzA-2qzuA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 8 VAL A 286
TYR A 279
GLY A  40
ALA A  42
 None
 0.87A 2a1hA-2qzuA:
undetectable
2a1hB-2qzuA:
undetectable		 2a1hA-2qzuA:
20.52
2a1hB-2qzuA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 7 ILE A 293
PRO A 239
GLY A 200
TRP A 199
 None
 1.16A 2pnjB-2qzuA:
undetectable		 2pnjB-2qzuA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 7 ILE A 276
THR A  53
ILE A 261
GLY A  40
 None
 0.90A 2v0mB-2qzuA:
undetectable		 2v0mB-2qzuA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 5 GLN A 380
THR A 378
HIS A 164
LEU A 109
 None
 1.10A 2zj0A-2qzuA:
undetectable		 2zj0A-2qzuA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 5 GLN A 380
THR A 378
HIS A 164
LEU A 109
 None
 1.09A 3ce6A-2qzuA:
undetectable		 3ce6A-2qzuA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 5 GLN A 380
THR A 378
HIS A 164
LEU A 109
 None
 1.08A 3ce6C-2qzuA:
undetectable		 3ce6C-2qzuA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 5 GLN A 380
THR A 378
HIS A 164
LEU A 109
 None
 1.09A 3ce6D-2qzuA:
undetectable		 3ce6D-2qzuA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 11 PRO A 343
LEU A 340
LEU A  59
ILE A 346
SER A  61
 None
 1.43A 3h6tA-2qzuA:
undetectable
3h6tC-2qzuA:
undetectable		 3h6tA-2qzuA:
18.95
3h6tC-2qzuA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 11 ILE A 346
SER A  61
PRO A 343
LEU A 340
LEU A  59
 None
 1.39A 3h6tA-2qzuA:
undetectable
3h6tC-2qzuA:
undetectable		 3h6tA-2qzuA:
18.95
3h6tC-2qzuA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_2
(POL POLYPROTEIN)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 9 ARG A 292
ALA A  35
ASP A  36
GLY A 131
ILE A 130
 None
 1.10A 3u7sB-2qzuA:
undetectable		 3u7sB-2qzuA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 12 TYR A 242
GLY A 200
LEU A 179
TYR A 177
ALA A 205
 None
 1.20A 3vywA-2qzuA:
undetectable		 3vywA-2qzuA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 12 TYR A 242
GLY A 200
LEU A 179
TYR A 177
ALA A 205
 None
 1.17A 3vywD-2qzuA:
undetectable		 3vywD-2qzuA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 12 ALA A 205
SER A 206
THR A 306
PHE A 222
ASN A 213
 None
 1.23A 4c49A-2qzuA:
undetectable		 4c49A-2qzuA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 5 GLN A 380
THR A 378
HIS A 164
LEU A 109
 None
 0.97A 4lvcA-2qzuA:
undetectable		 4lvcA-2qzuA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 5 GLN A 380
THR A 378
HIS A 164
LEU A 109
 None
 0.98A 4lvcC-2qzuA:
undetectable		 4lvcC-2qzuA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 8 VAL A 388
LEU A 354
ILE A  70
GLN A 399
THR A 381
 None
 1.46A 4ma7A-2qzuA:
undetectable		 4ma7A-2qzuA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 12 ASN A 229
SER A  76
ASP A 313
ASN A  99
ASN A 155
 None
 1.30A 4obwC-2qzuA:
undetectable		 4obwC-2qzuA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 6 LEU A 384
MET A 338
LEU A 361
ILE A 375
 None
 1.08A 4okxA-2qzuA:
undetectable		 4okxA-2qzuA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 12 ILE A 261
ALA A 320
ASP A 260
TYR A 280
GLU A  49
 None
 1.24A 4xt8A-2qzuA:
undetectable		 4xt8A-2qzuA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 5 TYR A 235
GLY A 325
TYR A 271
GLY A 269
 None
 1.04A 5ayfA-2qzuA:
undetectable		 5ayfA-2qzuA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 12 GLY A 325
TYR A 280
ILE A 245
TYR A 246
GLY A 285
 None
 0.99A 5eskA-2qzuA:
undetectable		 5eskA-2qzuA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 6 GLY A  44
ILE A 316
ARG A  39
TYR A 246
 None
 0.88A 5iwuA-2qzuA:
undetectable		 5iwuA-2qzuA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		3 / 3 THR A  67
SER A 351
ASP A  57
 None
 0.78A 5kvaA-2qzuA:
undetectable		 5kvaA-2qzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		3 / 3 THR A  67
SER A 351
ASP A  57
 None
 0.82A 5kvaB-2qzuA:
undetectable		 5kvaB-2qzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 8 TYR A 129
CYH A 115
TRP A 133
LEU A 109
 None
 1.40A 5kxiA-2qzuA:
undetectable
5kxiB-2qzuA:
undetectable		 5kxiA-2qzuA:
22.67
5kxiB-2qzuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 8 TYR A 129
CYH A 115
TRP A 133
LEU A 109
 None
 1.43A 5kxiD-2qzuA:
undetectable
5kxiE-2qzuA:
undetectable		 5kxiD-2qzuA:
22.67
5kxiE-2qzuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 10 ILE A 294
LEU A 297
ILE A 209
ALA A 208
ILE A 212
 None
 0.99A 5mvmD-2qzuA:
undetectable
5mvmE-2qzuA:
undetectable		 5mvmD-2qzuA:
10.53
5mvmE-2qzuA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 10 LEU A 297
ILE A 209
ALA A 208
ILE A 212
ILE A 130
 None
 0.96A 5mvmD-2qzuA:
undetectable
5mvmE-2qzuA:
undetectable		 5mvmD-2qzuA:
10.53
5mvmE-2qzuA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_2
(-)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 4 GLN A 380
THR A 378
HIS A 164
LEU A 109
 None
 0.99A 6f3nB-2qzuA:
undetectable		 6f3nB-2qzuA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 5 GLN A 380
THR A 378
HIS A 164
LEU A 109
 None
 1.00A 6gbnA-2qzuA:
undetectable		 6gbnA-2qzuA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		4 / 5 GLN A 380
THR A 378
HIS A 164
LEU A 109
 None
 1.01A 6gbnD-2qzuA:
undetectable		 6gbnD-2qzuA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2qzu PUTATIVE SULFATASE
YIDJ
(Bacteroides
fragilis) 		5 / 10 TRP A 116
ALA A 359
LEU A  83
GLY A  81
LEU A 297
 None
 1.42A 6hqbA-2qzuA:
undetectable
6hqbJ-2qzuA:
undetectable		 6hqbA-2qzuA:
9.18
6hqbJ-2qzuA:
6.52