SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qzw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
PRO A 120
ILE A 123
 None
 0.66A 1c6yB-2qzwA:
7.1		 1c6yB-2qzwA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
PRO A 120
ILE A 123
 None
 0.96A 1c6zA-2qzwA:
6.9		 1c6zA-2qzwA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
GLY A  83
ILE A 123
 None
 0.68A 1hxbA-2qzwA:
7.4		 1hxbA-2qzwA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		3 / 3 THR A 115
PRO A  41
THR A 117
 None
 0.82A 209dC-2qzwA:
undetectable		 209dC-2qzwA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 5 LEU A 216
ASP A 218
ALA A 303
ILE A 305
 None
 0.85A 2aofB-2qzwA:
7.6		 2aofB-2qzwA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 5 LEU A 216
ASP A 218
ALA A 303
ILE A 305
 None
 0.84A 2aohB-2qzwA:
7.7		 2aohB-2qzwA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
GLY A  83
ILE A 123
 None
 0.56A 2avsA-2qzwA:
7.8		 2avsA-2qzwA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 GLY A 125
ILE A 119
GLY A 122
VAL A  40
ILE A  82
 None
 1.11A 2avsB-2qzwA:
6.5		 2avsB-2qzwA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
GLY A  83
ILE A 123
 None
 0.59A 2avvA-2qzwA:
7.2		 2avvA-2qzwA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
GLY A  83
ILE A 123
 None
 0.58A 2avvD-2qzwA:
7.1		 2avvD-2qzwA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
PRO A 120
ILE A 123
 None
 0.89A 2avvD-2qzwA:
7.1		 2avvD-2qzwA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 LEU A 216
ASP A 218
GLY A 220
ALA A 303
ILE A 305
 None
 0.81A 2nmyB-2qzwA:
7.0		 2nmyB-2qzwA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 LEU A 216
ASP A 218
GLY A 220
ALA A 303
ILE A 305
 None
 0.80A 2nmzA-2qzwA:
7.5		 2nmzA-2qzwA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 LEU A 216
ASP A 218
GLY A 220
ALA A 303
ILE A 305
 None
 0.81A 2nmzB-2qzwA:
7.9		 2nmzB-2qzwA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_1
(PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 11 GLY A 103
ALA A 104
ILE A 170
PRO A 141
VAL A 140
 None
 0.93A 2nnpA-2qzwA:
7.4		 2nnpA-2qzwA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 11 ASP A  32
GLY A  34
ASP A  37
ILE A  82
ILE A 123
 None
 0.74A 2r5qB-2qzwA:
7.4		 2r5qB-2qzwA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 10 ASP A  32
GLY A  34
ASP A  37
ILE A  82
ILE A 123
 None
 0.74A 2r5qD-2qzwA:
7.9		 2r5qD-2qzwA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 LEU A 216
ASP A 218
GLY A 220
ALA A 303
ILE A 305
 None
 0.77A 2rkfB-2qzwA:
7.9		 2rkfB-2qzwA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 7 PHE A 279
PHE A 264
ILE A 208
GLY A 260
 None
 1.02A 2v0mC-2qzwA:
undetectable		 2v0mC-2qzwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_C_C41C1328_1
(RENIN)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		6 / 12 ASP A  32
GLY A  34
SER A  35
PRO A 120
ASP A 218
GLY A 220
 None
 1.16A 2v0zC-2qzwA:
35.6		 2v0zC-2qzwA:
26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_C_C41C1328_1
(RENIN)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		6 / 12 ASP A  32
GLY A  34
SER A  35
TYR A  84
ASP A 218
GLY A 220
 None
 0.29A 2v0zC-2qzwA:
35.6		 2v0zC-2qzwA:
26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_C_C41C1328_1
(RENIN)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A 218
GLY A 220
ASP A  32
GLY A  34
SER A  36
 None
 0.89A 2v0zC-2qzwA:
35.6		 2v0zC-2qzwA:
26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_1
(RENIN)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		6 / 12 ASP A 218
GLY A 220
ASP A  32
GLY A  34
SER A  36
ILE A 119
 None
 1.00A 2v0zO-2qzwA:
35.4		 2v0zO-2qzwA:
26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		3 / 3 PHE A 279
SER A 313
LEU A 311
 None
 0.83A 2w1bA-2qzwA:
undetectable		 2w1bA-2qzwA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_A_EV1A1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 TYR A 318
LEU A 306
VAL A 215
ILE A 325
PHE A 266
 None
 1.00A 2weyA-2qzwA:
undetectable		 2weyA-2qzwA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 8 LEU A 198
ILE A 213
LEU A 226
THR A 224
LEU A 306
 None
 1.45A 2xfhA-2qzwA:
undetectable		 2xfhA-2qzwA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 8 LEU A 327
ALA A 314
LEU A 306
GLY A 307
ASP A 218
 None
 1.48A 2yfxA-2qzwA:
undetectable		 2yfxA-2qzwA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 5 LEU A 216
ASP A 218
ILE A 305
GLY A  34
 None
 0.47A 3bufA-2qzwA:
31.4		 3bufA-2qzwA:
25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
GLY A  83
ILE A 123
 None
 0.58A 3cyxB-2qzwA:
7.3		 3cyxB-2qzwA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_1
(HIV-1 PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
GLY A  85
ILE A 123
 None
 0.83A 3d1zA-2qzwA:
7.7		 3d1zA-2qzwA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_1
(HIV-1 PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
PRO A 120
ILE A 123
 None
 0.91A 3d1zA-2qzwA:
7.7		 3d1zA-2qzwA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 11 ASP A  32
GLY A  34
ASP A  37
PRO A 120
ILE A 123
 None
 0.93A 3ekxA-2qzwA:
7.0		 3ekxA-2qzwA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 8 ASP A  32
GLY A  34
ASP A  37
ILE A 123
 None
 0.59A 3el0A-2qzwA:
6.7		 3el0A-2qzwA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 11 LEU A 311
ILE A 325
LEU A 327
PHE A 266
THR A 224
 None
 1.34A 3fl9C-2qzwA:
undetectable		 3fl9C-2qzwA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_C_SRYC403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASN A 309
ASP A 308
SER A 219
SER A  35
ASP A  32
 None
 1.50A 3havC-2qzwA:
undetectable		 3havC-2qzwA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		3 / 3 LEU A 316
LEU A 157
ARG A 312
 None
 0.62A 3hcnB-2qzwA:
undetectable		 3hcnB-2qzwA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 TYR A 315
LEU A 183
SER A 336
ILE A 170
GLY A 172
 None
 1.08A 3kk6A-2qzwA:
undetectable		 3kk6A-2qzwA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 TYR A 315
LEU A 183
SER A 336
ILE A 170
GLY A 172
 None
 1.08A 3kk6B-2qzwA:
undetectable		 3kk6B-2qzwA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		6 / 11 ILE A 126
ILE A 106
SER A 105
ILE A  18
VAL A  99
GLY A 100
 None
 1.46A 3kw4A-2qzwA:
undetectable		 3kw4A-2qzwA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
PRO A 120
ILE A 123
 None
 0.76A 3ndwA-2qzwA:
7.5		 3ndwA-2qzwA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
PRO A 120
ILE A 123
 None
 0.83A 3ndxA-2qzwA:
7.5		 3ndxA-2qzwA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
GLY A  85
ILE A 123
 None
 0.81A 3nu5A-2qzwA:
7.7		 3nu5A-2qzwA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
PRO A 120
ILE A 123
 None
 0.90A 3oxcA-2qzwA:
7.3		 3oxcA-2qzwA:
14.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		8 / 12 ASP A  32
GLY A  34
GLY A  85
ASP A  86
ASP A 218
THR A 221
TYR A 225
ILE A 305
 None
 0.49A 3prsA-2qzwA:
36.2		 3prsA-2qzwA:
30.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  85
THR A 221
TYR A 225
ILE A 305
 None
 0.58A 3pwwA-2qzwA:
36.0		 3pwwA-2qzwA:
30.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		7 / 8 GLY A  34
SER A  35
ILE A  82
TYR A  84
SER A  88
ASP A 218
THR A 222
 None
 0.38A 3pwwA-2qzwA:
36.0		 3pwwA-2qzwA:
30.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 8 ILE A  82
TYR A  84
ASP A  86
SER A  88
THR A 222
 None
 0.67A 3pwwA-2qzwA:
36.0		 3pwwA-2qzwA:
30.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		7 / 12 GLY A  85
SER A  88
ILE A 119
GLU A 193
THR A 221
TYR A 225
ILE A 305
 None
 0.92A 3q70A-2qzwA:
52.3		 3q70A-2qzwA:
73.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		11 / 12 ILE A  30
ASP A  32
GLY A  34
GLY A  85
ILE A 119
ASN A 131
GLU A 193
ASP A 218
THR A 221
TYR A 225
ILE A 305
 None
 0.50A 3q70A-2qzwA:
52.3		 3q70A-2qzwA:
73.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		10 / 12 ILE A 123
ASP A  32
GLY A  34
GLY A  85
ILE A 119
GLU A 193
ASP A 218
THR A 221
TYR A 225
ILE A 305
 None
 1.29A 3q70A-2qzwA:
52.3		 3q70A-2qzwA:
73.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 6 SER A  35
ILE A  82
TYR A  84
THR A 222
 None
 0.25A 3q70A-2qzwA:
52.3		 3q70A-2qzwA:
73.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 8 ALA A 112
ILE A 114
ALA A 133
ALA A 134
 None
 0.71A 3r9tA-2qzwA:
undetectable		 3r9tA-2qzwA:
22.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		10 / 12 ILE A  30
ASP A  32
GLY A  34
ILE A  82
GLY A  85
ASP A  86
SER A  88
ASP A 218
TYR A 225
ILE A 305
 None
 0.63A 3tneA-2qzwA:
48.3		 3tneA-2qzwA:
52.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		10 / 12 ILE A  30
ASP A  32
GLY A  34
ILE A  82
GLY A  85
SER A  88
ASN A 131
ASP A 218
TYR A 225
ILE A 305
 None
 0.59A 3tneA-2qzwA:
48.3		 3tneA-2qzwA:
52.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		9 / 12 ILE A 123
ASP A  32
GLY A  34
GLY A  85
ASP A  86
SER A  88
ASP A 218
TYR A 225
ILE A 305
 None
 1.24A 3tneA-2qzwA:
48.3		 3tneA-2qzwA:
52.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 6 SER A  35
TYR A  84
THR A 221
THR A 222
 None
 0.38A 3tneA-2qzwA:
48.3		 3tneA-2qzwA:
52.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		10 / 12 ILE A  30
ASP A  32
GLY A  34
ILE A  82
GLY A  85
ASP A  86
SER A  88
ASN A 131
ASP A 218
ILE A 305
 None
 0.60A 3tneB-2qzwA:
48.5		 3tneB-2qzwA:
52.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		8 / 12 ILE A 123
ASP A  32
GLY A  34
GLY A  85
ASP A  86
SER A  88
ASP A 218
ILE A 305
 None
 1.26A 3tneB-2qzwA:
48.5		 3tneB-2qzwA:
52.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 7 ILE A 119
THR A 221
THR A 222
TYR A 225
 None
 0.88A 3tneB-2qzwA:
48.5		 3tneB-2qzwA:
52.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		6 / 7 SER A  35
TYR A  84
ILE A 123
THR A 221
THR A 222
TYR A 225
 None
 0.42A 3tneB-2qzwA:
48.5		 3tneB-2qzwA:
52.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 5 TYR A 137
SER A  35
ASP A  97
ILE A  20
 None
 1.30A 3uj7B-2qzwA:
undetectable		 3uj7B-2qzwA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 8 ASP A  97
ILE A  20
GLY A  21
VAL A  29
 None
 0.86A 4acbB-2qzwA:
undetectable
4acbC-2qzwA:
undetectable		 4acbB-2qzwA:
22.86
4acbC-2qzwA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 6 THR A 197
ILE A 196
THR A 224
PHE A 310
 None
 1.05A 4acbC-2qzwA:
undetectable		 4acbC-2qzwA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 GLY A 100
ALA A 104
VAL A 149
VAL A  99
GLN A 109
 None
 1.38A 4df3B-2qzwA:
undetectable		 4df3B-2qzwA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 10 ASP A  32
GLY A  34
ASP A  37
GLY A  83
ILE A 123
 None
 0.82A 4dqfB-2qzwA:
7.6		 4dqfB-2qzwA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASN A  28
ASP A  17
ILE A  18
VAL A  99
PHE A 101
 None
 1.16A 4dx5B-2qzwA:
undetectable		 4dx5B-2qzwA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		6 / 12 VAL A 274
ALA A 314
LEU A 217
PHE A 266
PHE A 264
VAL A 230
 None
 1.45A 4eckA-2qzwA:
undetectable		 4eckA-2qzwA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 8 ASP A 302
ASN A 304
THR A 221
GLY A  85
 None
 1.01A 4fo4A-2qzwA:
undetectable		 4fo4A-2qzwA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 11 ASP A  32
GLY A  34
ASP A  37
PRO A 120
ILE A 123
 None
 0.85A 4njvB-2qzwA:
7.2		 4njvB-2qzwA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_2
(PROTEASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
PRO A 120
ILE A 123
 None
 0.76A 4njvD-2qzwA:
7.3		 4njvD-2qzwA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 5 THR A  72
THR A  98
ASP A  97
TYR A  65
 None
 1.26A 4oltA-2qzwA:
undetectable		 4oltA-2qzwA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASN A 139
VAL A 140
GLN A 109
LEU A  76
GLY A 135
 None
 1.31A 4qckA-2qzwA:
0.0		 4qckA-2qzwA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 5 THR A  72
THR A  98
ASP A  97
TYR A  65
 None
 1.25A 4qwpB-2qzwA:
undetectable		 4qwpB-2qzwA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ILE A 170
GLN A   1
ALA A   2
ILE A 338
SER A 336
 None
 1.22A 4uroC-2qzwA:
undetectable		 4uroC-2qzwA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ALA A 177
TYR A  14
ILE A  30
GLY A  34
LEU A 311
 None
 1.09A 5eshA-2qzwA:
undetectable		 5eshA-2qzwA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 9 ILE A 272
THR A 224
ASN A 265
LEU A 198
LEU A 226
 None
 1.44A 5fhzB-2qzwA:
undetectable		 5fhzB-2qzwA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 7 LEU A 306
THR A 224
ILE A 234
LEU A 296
 None
 0.78A 5fxtA-2qzwA:
undetectable		 5fxtA-2qzwA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 8 THR A 224
LEU A 298
ILE A 234
LEU A 296
 None
 0.80A 5g48A-2qzwA:
undetectable		 5g48A-2qzwA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_B_1FLB1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 9 LEU A 306
THR A 224
LEU A 298
ILE A 234
LEU A 296
 None
 0.85A 5g48B-2qzwA:
undetectable		 5g48B-2qzwA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 GLY A 103
ALA A 104
ILE A 170
PRO A 141
VAL A 140
 None
 0.86A 5kqxA-2qzwA:
7.3		 5kqxA-2qzwA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		4 / 8 ASP A 323
TYR A 128
GLY A 125
ASN A 153
 None
 1.08A 6giqL-2qzwA:
undetectable
6giqP-2qzwA:
undetectable
6giqT-2qzwA:
undetectable		 6giqL-2qzwA:
24.78
6giqP-2qzwA:
20.12
6giqT-2qzwA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 2qzw CANDIDAPEPSIN-1
(Candida
albicans) 		5 / 12 ASN A 309
VAL A 215
ILE A 235
ILE A 213
PHE A 264
 None
 1.02A 6j20A-2qzwA:
undetectable		 6j20A-2qzwA:
21.30