SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qzx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 10 LEU A 140
VAL A   5
VAL A 104
GLY A 102
LEU A 124
 None
 1.38A 1fk9A-2qzxA:
undetectable		 1fk9A-2qzxA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKV_A_EFZA2000_1
(POL POLYPROTEIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 9 LEU A 140
VAL A   5
VAL A 104
GLY A 102
LEU A 124
 None
 1.45A 1ikvA-2qzxA:
undetectable		 1ikvA-2qzxA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKW_A_EFZA2000_1
(POL POLYPROTEIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 10 LEU A 140
VAL A   5
VAL A 104
GLY A 102
LEU A 124
 None
 1.45A 1ikwA-2qzxA:
undetectable		 1ikwA-2qzxA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 11 LEU A 140
VAL A   5
VAL A 104
GLY A 102
LEU A 124
 None
 1.34A 1jkhA-2qzxA:
undetectable
1jkhB-2qzxA:
undetectable		 1jkhA-2qzxA:
20.32
1jkhB-2qzxA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 VAL A 196
LEU A 216
LEU A 217
SER A 219
LEU A 157
 None
 1.21A 1kw0A-2qzxA:
undetectable		 1kw0A-2qzxA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 10 LEU A 140
VAL A   5
VAL A 104
GLY A 102
LEU A 124
 None
 1.39A 1lw0A-2qzxA:
undetectable		 1lw0A-2qzxA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 9 LEU A 140
VAL A   5
VAL A 104
GLY A 102
LEU A 124
 None
 1.44A 1lwfA-2qzxA:
undetectable		 1lwfA-2qzxA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMK_A_H4BA1427_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 VAL A 196
LEU A 194
LEU A 217
SER A 219
LEU A 159
 None
 1.34A 1mmkA-2qzxA:
undetectable		 1mmkA-2qzxA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMK_A_H4BA1427_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 VAL A 196
LEU A 216
LEU A 217
SER A 219
LEU A 157
 None
 1.26A 1mmkA-2qzxA:
undetectable		 1mmkA-2qzxA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 ILE A  18
GLY A  21
VAL A  99
ALA A  68
SER A  69
 None
 1.24A 1nbhA-2qzxA:
undetectable		 1nbhA-2qzxA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 ILE A  18
GLY A  21
VAL A  99
ALA A  68
SER A  69
 None
 1.24A 1nbhC-2qzxA:
undetectable		 1nbhC-2qzxA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 ILE A  18
GLY A  21
VAL A  99
ALA A  68
SER A  69
 None
 1.23A 1nbhD-2qzxA:
undetectable		 1nbhD-2qzxA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 11 LEU A 159
ALA A 314
LEU A 217
LEU A 306
SER A 224
 None
 1.29A 1tz8A-2qzxA:
undetectable
1tz8B-2qzxA:
undetectable		 1tz8A-2qzxA:
18.81
1tz8B-2qzxA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
ILE A  82
ILE A 123
 None
 0.90A 2f8gB-2qzxA:
7.2		 2f8gB-2qzxA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 11 LEU A 216
ASP A 218
GLY A 220
GLY A 125
ILE A 126
 None
 1.13A 2fxdA-2qzxA:
7.2		 2fxdA-2qzxA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
ALA A 119
ILE A 123
 None
 0.90A 2nmzB-2qzxA:
7.2		 2nmzB-2qzxA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 11 ASP A  32
GLY A  34
ASP A  37
ILE A  82
ILE A 123
 None
 0.89A 2r5qB-2qzxA:
7.3		 2r5qB-2qzxA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 10 ASP A  32
GLY A  34
ASP A  37
ILE A  82
ILE A 123
 None
 0.89A 2r5qD-2qzxA:
7.8		 2r5qD-2qzxA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_C_C41C1328_1
(RENIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		6 / 12 ASP A  32
GLY A  34
SER A  35
TYR A  84
ASP A 218
GLY A 220
 None
 0.36A 2v0zC-2qzxA:
36.0		 2v0zC-2qzxA:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_C_C41C1328_1
(RENIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 ASP A 218
GLY A 220
ASP A  32
GLY A  34
SER A  36
 None
 0.87A 2v0zC-2qzxA:
36.0		 2v0zC-2qzxA:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_1
(RENIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 ASP A 218
GLY A 220
ASP A  32
GLY A  34
SER A  36
 None
 0.88A 2v0zO-2qzxA:
35.9		 2v0zO-2qzxA:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		3 / 3 THR A 166
SER A 334
LYS A 178
 None
 1.11A 3aocC-2qzxA:
undetectable		 3aocC-2qzxA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		4 / 5 LEU A 216
ASP A 218
ILE A 305
GLY A  34
 None
 0.59A 3bufA-2qzxA:
32.2		 3bufA-2qzxA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		4 / 8 ASP A  32
GLY A  34
ASP A  37
ILE A 123
 None
 0.54A 3el0A-2qzxA:
6.7		 3el0A-2qzxA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 TYR A 315
LEU A 183
SER A 336
ILE A 170
GLY A 172
 None
 1.20A 3kk6B-2qzxA:
undetectable		 3kk6B-2qzxA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 SER A 190
ILE A 325
LEU A 217
ASP A 218
PHE A 128
 None
 0.95A 3ko0A-2qzxA:
undetectable
3ko0B-2qzxA:
undetectable
3ko0C-2qzxA:
undetectable
3ko0D-2qzxA:
undetectable		 3ko0A-2qzxA:
17.17
3ko0B-2qzxA:
17.17
3ko0C-2qzxA:
17.17
3ko0D-2qzxA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 11 PHE A 128
LEU A 217
ASP A 218
SER A 190
ILE A 325
 None
 0.96A 3ko0A-2qzxA:
undetectable
3ko0B-2qzxA:
undetectable
3ko0I-2qzxA:
undetectable
3ko0J-2qzxA:
undetectable		 3ko0A-2qzxA:
17.17
3ko0B-2qzxA:
17.17
3ko0I-2qzxA:
17.17
3ko0J-2qzxA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 SER A 190
ILE A 325
LEU A 217
ASP A 218
PHE A 128
 None
 0.96A 3ko0M-2qzxA:
undetectable
3ko0N-2qzxA:
undetectable
3ko0O-2qzxA:
undetectable
3ko0P-2qzxA:
undetectable		 3ko0M-2qzxA:
17.17
3ko0N-2qzxA:
17.17
3ko0O-2qzxA:
17.17
3ko0P-2qzxA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		3 / 3 ASP A  86
SER A  88
ARG A 120
 None
 0.59A 3loqA-2qzxA:
undetectable		 3loqA-2qzxA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP1_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 10 LEU A 140
VAL A   5
VAL A 104
GLY A 102
LEU A 124
 None
 1.37A 3lp1A-2qzxA:
undetectable		 3lp1A-2qzxA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		8 / 12 ASP A  32
GLY A  34
GLY A  85
ASP A  86
ASP A 218
THR A 221
TYR A 225
ILE A 305
 None
 0.58A 3prsA-2qzxA:
36.0		 3prsA-2qzxA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 ASP A  32
GLY A  85
THR A 221
TYR A 225
ILE A 305
 None
 0.45A 3pwwA-2qzxA:
35.9		 3pwwA-2qzxA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		7 / 8 GLY A  34
SER A  35
ILE A  82
TYR A  84
SER A  88
ASP A 218
THR A 222
 None
 0.34A 3pwwA-2qzxA:
35.9		 3pwwA-2qzxA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		7 / 8 SER A  35
ILE A  82
TYR A  84
ASP A  86
SER A  88
ASP A 218
THR A 222
 None
 0.57A 3pwwA-2qzxA:
35.9		 3pwwA-2qzxA:
29.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		8 / 12 ILE A  30
ASP A  32
GLY A  34
GLY A  85
ASP A 218
THR A 221
TYR A 225
ILE A 305
 None
 0.41A 3q70A-2qzxA:
50.4		 3q70A-2qzxA:
56.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		6 / 12 ILE A 123
ASP A  32
ASP A 218
THR A 221
TYR A 225
ILE A 305
 None
 1.12A 3q70A-2qzxA:
50.4		 3q70A-2qzxA:
56.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		6 / 12 ILE A 123
ASP A  32
ILE A  82
ASP A 218
TYR A 225
ILE A 305
 None
 1.39A 3q70A-2qzxA:
50.4		 3q70A-2qzxA:
56.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 6 THR A  13
SER A  35
ILE A  82
TYR A  84
THR A 222
 None
 0.30A 3q70A-2qzxA:
50.4		 3q70A-2qzxA:
56.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		10 / 12 ILE A  30
ASP A  32
GLY A  34
ILE A  82
GLY A  85
ASP A  86
SER A  88
ASP A 218
TYR A 225
ILE A 305
 None
 0.53A 3tneA-2qzxA:
47.6		 3tneA-2qzxA:
46.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		9 / 12 ILE A 123
ASP A  32
GLY A  34
GLY A  85
ASP A  86
SER A  88
ASP A 218
TYR A 225
ILE A 305
 None
 1.33A 3tneA-2qzxA:
47.6		 3tneA-2qzxA:
46.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		4 / 6 SER A  35
TYR A  84
THR A 221
THR A 222
 None
 0.24A 3tneA-2qzxA:
47.6		 3tneA-2qzxA:
46.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		10 / 12 ILE A  30
ASP A  32
GLY A  34
ILE A  82
GLY A  85
ASP A  86
SER A  88
ASP A 218
ASP A 303
ILE A 305
 None
 0.59A 3tneB-2qzxA:
47.7		 3tneB-2qzxA:
46.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		9 / 12 ILE A 123
ASP A  32
GLY A  34
GLY A  85
ASP A  86
SER A  88
ASP A 218
ASP A 303
ILE A 305
 None
 1.27A 3tneB-2qzxA:
47.7		 3tneB-2qzxA:
46.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		6 / 7 SER A  35
TYR A  84
ILE A 123
THR A 221
THR A 222
TYR A 225
 None
 0.35A 3tneB-2qzxA:
47.7		 3tneB-2qzxA:
46.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		4 / 5 ASP A 175
GLU A 335
TYR A 158
GLN A 168
 None
 0.93A 3w9tE-2qzxA:
undetectable		 3w9tE-2qzxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		4 / 5 ASP A 175
GLU A 335
TYR A 158
GLN A 168
 None
 0.97A 3w9tG-2qzxA:
undetectable		 3w9tG-2qzxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		4 / 7 ASP A  23
ASP A  97
SER A  73
SER A  70
 None
 1.26A 4k7gB-2qzxA:
undetectable		 4k7gB-2qzxA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		4 / 6 SER A  88
GLY A 125
ASP A  37
GLY A  34
 None
 1.00A 4koeA-2qzxA:
undetectable
4koeB-2qzxA:
undetectable
4koeC-2qzxA:
undetectable		 4koeA-2qzxA:
23.11
4koeB-2qzxA:
23.11
4koeC-2qzxA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		4 / 7 SER A  88
GLY A 125
ASP A  37
GLY A  34
 None
 0.95A 4koeA-2qzxA:
undetectable
4koeB-2qzxA:
undetectable
4koeD-2qzxA:
undetectable		 4koeA-2qzxA:
23.11
4koeB-2qzxA:
23.11
4koeD-2qzxA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 11 THR A  33
LEU A 140
VAL A   5
ILE A 169
LEU A 157
 None
 1.49A 4lhmA-2qzxA:
undetectable		 4lhmA-2qzxA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		4 / 5 THR A  72
THR A  98
ASP A  97
TYR A  65
 None
 1.37A 4oltA-2qzxA:
undetectable		 4oltA-2qzxA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		4 / 5 THR A  72
THR A  98
ASP A  97
TYR A  65
 None
 1.36A 4qwpA-2qzxA:
undetectable		 4qwpA-2qzxA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4J_A_LNRA412_1
(ENDOTHIAPEPSIN)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 9 ASP A  32
TYR A  84
ASP A  86
SER A  88
SER A 118
 None
 1.09A 4y4jA-2qzxA:
36.1		 4y4jA-2qzxA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 VAL A  29
ILE A  18
GLY A 100
VAL A   3
LEU A 144
 None
 0.85A 4y8wA-2qzxA:
undetectable		 4y8wA-2qzxA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 VAL A  29
ILE A  18
GLY A 100
VAL A   3
LEU A 144
 None
 0.89A 4y8wB-2qzxA:
undetectable		 4y8wB-2qzxA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 VAL A  29
ILE A  18
GLY A 100
VAL A   3
LEU A 144
 None
 0.87A 4y8wC-2qzxA:
undetectable		 4y8wC-2qzxA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		4 / 6 GLY A 125
ASP A  37
GLY A  34
SER A  88
 None
 0.95A 4z53A-2qzxA:
undetectable
4z53B-2qzxA:
undetectable		 4z53A-2qzxA:
22.06
4z53B-2qzxA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		4 / 7 GLY A 125
ASP A  37
GLY A  34
SER A  88
 None
 0.93A 4z53A-2qzxA:
undetectable
4z53B-2qzxA:
undetectable		 4z53A-2qzxA:
22.06
4z53B-2qzxA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 ALA A 177
TYR A  14
ILE A  30
GLY A  34
LEU A 311
 None
 1.16A 5eshA-2qzxA:
undetectable		 5eshA-2qzxA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		4 / 8 ILE A 174
GLY A 173
PHE A 128
ASN A 342
 None
 0.86A 5hieD-2qzxA:
undetectable		 5hieD-2qzxA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 8 LEU A 270
PHE A 266
PRO A 329
ALA A 314
PHE A 310
 None
 0.93A 5m0oC-2qzxA:
undetectable		 5m0oC-2qzxA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 10 LEU A 144
ILE A 142
ILE A 149
GLY A 148
LEU A 140
 None
 1.07A 5twjB-2qzxA:
undetectable		 5twjB-2qzxA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 12 LEU A 144
ILE A 142
ILE A 149
GLY A 148
LEU A 140
 None
 1.06A 5twjC-2qzxA:
undetectable		 5twjC-2qzxA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I5Z_D_SAMD401_0
(O-METHYLTRANSFERASE
1)		 2qzx CANDIDAPEPSIN-5
(Candida
albicans) 		5 / 11 SER A 224
GLY A  34
GLY A 220
ASP A  32
ASP A  37
 None
 0.95A 6i5zD-2qzxA:
undetectable		 6i5zD-2qzxA:
22.58