SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r0h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		5 / 12 ASP A 115
GLY A  94
ILE A  63
THR A 102
ILE A 114
 None
 1.02A 1c6zB-2r0hA:
undetectable		 1c6zB-2r0hA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		5 / 12 ILE A 114
PHE A 145
SER A 134
LEU A  50
ILE A 101
 None
 1.26A 2xkwB-2r0hA:
undetectable		 2xkwB-2r0hA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		4 / 6 HIS A  60
ARG A  64
ASN A  73
GLU A  84
 CTO  A 165 (-3.6A)
CTO  A 165 (-2.6A)
CTO  A 165 (-4.1A)
CTO  A 165 (-2.7A)
 0.45A 3galA-2r0hA:
15.8		 3galA-2r0hA:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		4 / 6 HIS A  60
ARG A  64
ASN A  73
GLU A  84
 CTO  A 165 (-3.6A)
CTO  A 165 (-2.6A)
CTO  A 165 (-4.1A)
CTO  A 165 (-2.7A)
 0.40A 3galB-2r0hA:
15.3		 3galB-2r0hA:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		3 / 3 ARG A 109
ASP A 105
ASP A 108
 None
 0.89A 3jb2A-2r0hA:
undetectable		 3jb2A-2r0hA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		3 / 3 ARG A 109
ASP A 105
ASP A 108
 None
 0.90A 3jb3A-2r0hA:
undetectable		 3jb3A-2r0hA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		3 / 3 PRO A  76
SER A  80
ASN A  73
 None
None
CTO  A 165 (-4.1A)
 0.93A 3lslG-2r0hA:
undetectable		 3lslG-2r0hA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		3 / 3 PHE A 145
GLN A 141
PHE A  93
 None
 0.59A 3rv5A-2r0hA:
undetectable		 3rv5A-2r0hA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		5 / 12 LEU A   5
HIS A  60
PRO A 143
PHE A 145
ILE A  63
 None
CTO  A 165 (-3.6A)
None
None
None
 1.42A 5dv4A-2r0hA:
undetectable		 5dv4A-2r0hA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		5 / 12 PHE A  70
ILE A  61
VAL A  48
PHE A 145
VAL A 119
 None
 1.34A 6ap6A-2r0hA:
undetectable		 6ap6A-2r0hA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		5 / 12 PHE A  70
ILE A  61
VAL A  48
PHE A 145
VAL A 119
 None
 1.35A 6ap6B-2r0hA:
undetectable		 6ap6B-2r0hA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		5 / 7 HIS A  60
ARG A  64
ASN A  73
GLU A  84
ARG A  86
 CTO  A 165 (-3.6A)
CTO  A 165 (-2.6A)
CTO  A 165 (-4.1A)
CTO  A 165 (-2.7A)
CTO  A 165 ( 4.0A)
 0.37A 6b8kA-2r0hA:
16.3		 6b8kA-2r0hA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		5 / 8 HIS A  60
ARG A  64
ASN A  73
GLU A  84
ARG A  86
 CTO  A 165 (-3.6A)
CTO  A 165 (-2.6A)
CTO  A 165 (-4.1A)
CTO  A 165 (-2.7A)
CTO  A 165 ( 4.0A)
 0.55A 6b94A-2r0hA:
14.4		 6b94A-2r0hA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		5 / 10 HIS A  60
ARG A  64
ASN A  73
GLU A  84
ARG A  86
 CTO  A 165 (-3.6A)
CTO  A 165 (-2.6A)
CTO  A 165 (-4.1A)
CTO  A 165 (-2.7A)
CTO  A 165 ( 4.0A)
 0.39A 6b94A-2r0hA:
14.4
6b94B-2r0hA:
13.8		 6b94A-2r0hA:
18.54
6b94B-2r0hA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		4 / 4 ARG A  64
GLU A  67
GLU A  84
ARG A  86
 CTO  A 165 (-2.6A)
CTO  A 165 ( 4.7A)
CTO  A 165 (-2.7A)
CTO  A 165 ( 4.0A)
 0.51A 6fk2A-2r0hA:
16.1		 6fk2A-2r0hA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 2r0h CGL3 LECTIN
(Coprinopsis
cinerea) 		4 / 4 ARG A  86
GLU A  84
GLU A  67
ARG A  64
 CTO  A 165 ( 4.0A)
CTO  A 165 (-2.7A)
CTO  A 165 ( 4.7A)
CTO  A 165 (-2.6A)
 1.00A 6fk2A-2r0hA:
16.1		 6fk2A-2r0hA:
25.00