SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r0j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 2r0j UBIQUITIN CARRIER
PROTEIN
(Plasmodium
falciparum) 		4 / 7 TYR A  60
ILE A  88
GLU A   9
LEU A  54
 None
 0.91A 1j96B-2r0jA:
undetectable		 1j96B-2r0jA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 2r0j UBIQUITIN CARRIER
PROTEIN
(Plasmodium
falciparum) 		4 / 4 VAL A 123
LEU A  52
ILE A 106
LEU A 110
 None
 1.04A 2byoA-2r0jA:
undetectable		 2byoA-2r0jA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2r0j UBIQUITIN CARRIER
PROTEIN
(Plasmodium
falciparum) 		5 / 12 LEU A  89
ILE A   6
ILE A  99
VAL A 102
LEU A 103
 None
 1.10A 3w67B-2r0jA:
undetectable		 3w67B-2r0jA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 2r0j UBIQUITIN CARRIER
PROTEIN
(Plasmodium
falciparum) 		5 / 12 ILE A   6
THR A  10
ALA A  23
LEU A  56
LEU A  54
 None
 1.42A 4pbhA-2r0jA:
undetectable		 4pbhA-2r0jA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 2r0j UBIQUITIN CARRIER
PROTEIN
(Plasmodium
falciparum) 		4 / 5 LEU A  52
LEU A  89
PHE A  69
LEU A 109
 None
 0.93A 5gtrA-2r0jA:
undetectable		 5gtrA-2r0jA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2r0j UBIQUITIN CARRIER
PROTEIN
(Plasmodium
falciparum) 		3 / 3 ILE A  84
VAL A  67
PRO A  65
 None
 0.62A 5uunA-2r0jA:
undetectable		 5uunA-2r0jA:
17.78