SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r1i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 2r1i GCN5-RELATED
N-ACETYLTRANSFERASE
(Arthrobacter
sp.
FB24) 		3 / 3 GLU A 134
LEU A 132
LEU A 124
 None
GOL  A 177 (-4.3A)
None
 0.71A 3ohtA-2r1iA:
undetectable		 3ohtA-2r1iA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 2r1i GCN5-RELATED
N-ACETYLTRANSFERASE
(Arthrobacter
sp.
FB24) 		3 / 3 GLU A 134
LEU A 132
LEU A 124
 None
GOL  A 177 (-4.3A)
None
 0.75A 3ohtB-2r1iA:
undetectable		 3ohtB-2r1iA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 2r1i GCN5-RELATED
N-ACETYLTRANSFERASE
(Arthrobacter
sp.
FB24) 		5 / 12 ALA A 120
SER A 121
GLY A  75
GLY A 110
LEU A 102
 None
 1.23A 4uilH-2r1iA:
undetectable
4uilL-2r1iA:
undetectable		 4uilH-2r1iA:
19.38
4uilL-2r1iA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 2r1i GCN5-RELATED
N-ACETYLTRANSFERASE
(Arthrobacter
sp.
FB24) 		5 / 9 LEU A 102
LEU A 113
GLY A 114
LEU A 117
ALA A  74
 None
 0.84A 5dqfA-2r1iA:
undetectable		 5dqfA-2r1iA:
14.90