SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r1z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2r1z BRCA1-ASSOCIATED
RING DOMAIN PROTEIN
1
(Homo
sapiens) 		4 / 5 PRO A 707
THR A 696
VAL A 695
GLY A 700
 None
 1.17A 3elzA-2r1zA:
undetectable		 3elzA-2r1zA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2r1z BRCA1-ASSOCIATED
RING DOMAIN PROTEIN
1
(Homo
sapiens) 		4 / 5 MET A 621
LEU A 694
PRO A 657
SER A 660
 None
None
None
GOL  A 801 ( 2.7A)
 1.50A 4kmmB-2r1zA:
undetectable		 4kmmB-2r1zA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2r1z BRCA1-ASSOCIATED
RING DOMAIN PROTEIN
1
(Homo
sapiens) 		5 / 12 PRO A 610
GLY A 576
SER A 575
THR A 617
SER A 579
 None
 1.02A 5hfjE-2r1zA:
undetectable		 5hfjE-2r1zA:
20.39