SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r25'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2r25 OSMOSENSING
HISTIDINE PROTEIN
KINASE SLN1
(Saccharomyces
cerevisiae) 		4 / 7 ILE B1197
PRO B1168
GLY B1191
MET B1189
 None
NA  B   5 (-4.4A)
None
None
 1.24A 2pnjB-2r25B:
3.6		 2pnjB-2r25B:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2r25 OSMOSENSING
HISTIDINE PROTEIN
KINASE SLN1
(Saccharomyces
cerevisiae) 		5 / 12 ASP B1177
ALA B1176
ASP B1151
THR B1156
SER B1179
 None
 1.38A 5hfjH-2r25B:
2.7		 5hfjH-2r25B:
21.57