SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r2a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 2r2a UNCHARACTERIZED
PROTEIN
(Neisseria
meningitidis) 		4 / 7 ASP A 134
GLN A 135
PRO A  98
GLN A  94
 None
 1.10A 3l2vA-2r2aA:
undetectable		 3l2vA-2r2aA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_2
(HIV-1 PROTEASE)		 2r2a UNCHARACTERIZED
PROTEIN
(Neisseria
meningitidis) 		5 / 10 VAL A  88
ILE A  78
VAL A 110
VAL A 125
ILE A 123
 None
 1.09A 3oxvB-2r2aA:
undetectable		 3oxvB-2r2aA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 2r2a UNCHARACTERIZED
PROTEIN
(Neisseria
meningitidis) 		4 / 5 ARG A 138
LEU A   6
VAL A 141
ASP A 165
 None
 0.92A 3ufnA-2r2aA:
undetectable
3ufnB-2r2aA:
undetectable		 3ufnA-2r2aA:
19.10
3ufnB-2r2aA:
19.10