SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r32'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 2r32 GCN4-PII/TUMOR
NECROSIS FACTOR
LIGAND SUPERFAMILY
MEMBER 18 FUSION
PROTEIN
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 LEU A 170
ILE A 176
GLY A  93
HIS A 143
LEU A 142
 None
 1.26A 2j7xA-2r32A:
undetectable		 2j7xA-2r32A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 2r32 GCN4-PII/TUMOR
NECROSIS FACTOR
LIGAND SUPERFAMILY
MEMBER 18 FUSION
PROTEIN
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 LEU A 170
ILE A 176
GLY A  93
HIS A 143
LEU A 142
 None
 1.24A 4j26A-2r32A:
undetectable		 4j26A-2r32A:
19.01