SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r37'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 2r37 GLUTATHIONE
PEROXIDASE 3
(Homo
sapiens) 		3 / 3 PHE A 132
ASN A  83
PHE A 128
 None
 1.07A 2zbuD-2r37A:
undetectable		 2zbuD-2r37A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 2r37 GLUTATHIONE
PEROXIDASE 3
(Homo
sapiens) 		5 / 10 PHE A  99
VAL A  64
PHE A 148
ILE A  54
PHE A 135
 None
 1.25A 3t3qB-2r37A:
undetectable		 3t3qB-2r37A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 2r37 GLUTATHIONE
PEROXIDASE 3
(Homo
sapiens) 		5 / 10 PHE A  99
VAL A  64
PHE A 148
ILE A  54
PHE A 135
 None
 1.23A 3t3qD-2r37A:
undetectable		 3t3qD-2r37A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 2r37 GLUTATHIONE
PEROXIDASE 3
(Homo
sapiens) 		3 / 3 ASN A 112
LEU A 119
PHE A 135
 None
 0.73A 4dajB-2r37A:
undetectable		 4dajB-2r37A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 2r37 GLUTATHIONE
PEROXIDASE 3
(Homo
sapiens) 		4 / 6 GLY A 192
VAL A 188
PRO A 190
GLY A  93
 None
 0.85A 4dxuA-2r37A:
undetectable		 4dxuA-2r37A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2r37 GLUTATHIONE
PEROXIDASE 3
(Homo
sapiens) 		4 / 6 GLN A 103
THR A 159
HIS A 199
ASN A  68
 None
 1.31A 4pfjB-2r37A:
undetectable		 4pfjB-2r37A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 2r37 GLUTATHIONE
PEROXIDASE 3
(Homo
sapiens) 		5 / 9 TYR A  53
ILE A  54
PHE A  56
GLY A  44
GLU A 136
 None
 1.22A 4yp2B-2r37A:
undetectable		 4yp2B-2r37A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 2r37 GLUTATHIONE
PEROXIDASE 3
(Homo
sapiens) 		5 / 9 TYR A  53
ILE A  54
PHE A  56
GLY A  44
GLU A 136
 None
 1.25A 5cf9B-2r37A:
undetectable		 5cf9B-2r37A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2r37 GLUTATHIONE
PEROXIDASE 3
(Homo
sapiens) 		3 / 3 ASN A 112
LEU A 119
PHE A 135
 None
 0.76A 5dsgA-2r37A:
undetectable		 5dsgA-2r37A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 2r37 GLUTATHIONE
PEROXIDASE 3
(Homo
sapiens) 		3 / 3 GLU A 184
TRP A 181
ASN A 141
 None
CL  A   1 (-4.7A)
None
 0.83A 5dv4A-2r37A:
undetectable		 5dv4A-2r37A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_B_ADNB401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 2r37 GLUTATHIONE
PEROXIDASE 3
(Homo
sapiens) 		5 / 12 GLN A 133
GLY A  50
ASP A  49
ILE A  48
ALA A  45
 None
 1.09A 6bq4B-2r37A:
undetectable		 6bq4B-2r37A:
18.65