SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r44'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDS_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 12 ILE A 296
ALA A 265
LYS A 290
THR A 241
ILE A 321
 None
None
PG4  A 338 ( 2.5A)
None
None
 1.08A 1ddsA-2r44A:
undetectable		 1ddsA-2r44A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 7 ASP A 147
GLY A 105
ILE A  88
ALA A 114
ILE A 112
 None
 1.28A 1n49A-2r44A:
undetectable		 1n49A-2r44A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 12 VAL A 214
ILE A 217
ILE A  17
PHE A 278
LEU A  65
 None
 0.98A 1qhsA-2r44A:
undetectable		 1qhsA-2r44A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_A_MTXA170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 12 ILE A 296
ALA A 265
LYS A 290
THR A 241
ILE A 321
 None
None
PG4  A 338 ( 2.5A)
None
None
 1.14A 1tdrA-2r44A:
undetectable		 1tdrA-2r44A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 5 LEU A 128
PHE A 175
VAL A 117
ALA A 114
 None
 1.12A 2cizA-2r44A:
undetectable		 2cizA-2r44A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 12 ASP A  72
GLY A 105
ILE A  88
ALA A 114
ILE A 112
 None
 0.89A 2nmyB-2r44A:
undetectable		 2nmyB-2r44A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 10 ASP A  72
GLY A 105
ILE A  88
ALA A 114
ILE A 112
 None
 0.90A 3ekpB-2r44A:
undetectable		 3ekpB-2r44A:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 10 ASP A  72
GLY A 105
ILE A  88
ALA A 114
ILE A 112
 None
 0.91A 3ekpC-2r44A:
undetectable		 3ekpC-2r44A:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 9 ASP A  72
GLY A 105
ILE A  88
ALA A 114
ILE A 112
 None
 0.93A 3ektB-2r44A:
undetectable		 3ektB-2r44A:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 7 MET A  69
LEU A  65
PRO A 149
GLY A  45
 None
 1.09A 3hcnA-2r44A:
undetectable		 3hcnA-2r44A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_A_KANA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 11 VAL A 271
ASN A 267
ALA A 260
HIS A 299
ASN A 298
 None
None
None
None
PG4  A 332 (-4.1A)
 1.29A 3kp5A-2r44A:
0.0		 3kp5A-2r44A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 12 GLY A  46
ARG A 300
LEU A 129
ILE A 112
PHE A 150
 None
 1.27A 3mneA-2r44A:
undetectable		 3mneA-2r44A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 12 GLY A  46
ARG A 300
LEU A 129
ILE A 112
PHE A 150
 None
 1.26A 3mnoA-2r44A:
undetectable		 3mnoA-2r44A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 12 GLY A  46
ARG A 300
LEU A 129
ILE A 112
PHE A 150
 None
 1.27A 3mnpA-2r44A:
undetectable		 3mnpA-2r44A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 12 THR A 262
HIS A 299
ASP A 173
ILE A 235
LEU A 268
 None
 1.32A 4pooA-2r44A:
undetectable		 4pooA-2r44A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 8 PRO A 106
LEU A  87
VAL A 117
VAL A 152
LEU A  82
 None
 1.41A 4pwdA-2r44A:
undetectable		 4pwdA-2r44A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 12 LEU A  71
PRO A  54
LEU A  50
ASN A  63
LEU A 151
 None
 1.23A 4x61A-2r44A:
undetectable		 4x61A-2r44A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 8 GLU A 189
LEU A 184
HIS A 180
LEU A 181
 None
PG4  A 342 (-4.2A)
None
PG4  A 342 ( 4.1A)
 1.11A 5dxeA-2r44A:
undetectable		 5dxeA-2r44A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 12 ILE A 296
ALA A 265
LYS A 290
THR A 241
ILE A 321
 None
None
PG4  A 338 ( 2.5A)
None
None
 1.06A 5e8qA-2r44A:
undetectable		 5e8qA-2r44A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 12 ILE A 296
ALA A 265
LYS A 290
THR A 241
ILE A 321
 None
None
PG4  A 338 ( 2.5A)
None
None
 1.13A 5e8qB-2r44A:
undetectable		 5e8qB-2r44A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 12 ILE A 296
ALA A 265
LYS A 290
THR A 241
ILE A 321
 None
None
PG4  A 338 ( 2.5A)
None
None
 1.10A 5eajB-2r44A:
undetectable		 5eajB-2r44A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 12 LEU A  71
PRO A  54
LEU A  50
ASN A  63
LEU A 151
 None
 1.30A 5emlA-2r44A:
undetectable		 5emlA-2r44A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 12 ILE A 296
ALA A 265
LYS A 290
THR A 241
ILE A 321
 None
None
PG4  A 338 ( 2.5A)
None
None
 1.12A 5ujxB-2r44A:
undetectable		 5ujxB-2r44A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		3 / 3 ASP A 147
ASN A 110
ASP A  70
 None
None
PG4  A 337 (-3.6A)
 0.83A 5vopA-2r44A:
undetectable		 5vopA-2r44A:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2r44 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 8 GLU A 189
LEU A 184
HIS A 180
LEU A 181
 None
PG4  A 342 (-4.2A)
None
PG4  A 342 ( 4.1A)
 1.09A 6cbzA-2r44A:
undetectable		 6cbzA-2r44A:
14.47