SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r5k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY5_A_ACTA600_0
(RIBONUCLEASE A)		 2r5k MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
10) 		4 / 4 HIS A 362
VAL A 114
ASN A 338
THR A 337
 None
 1.42A 1dy5A-2r5kA:
undetectable		 1dy5A-2r5kA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 2r5k MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
10) 		4 / 8 PHE A  70
LEU A  41
GLY A 105
ASP A 367
 None
 0.96A 1rmtC-2r5kA:
undetectable		 1rmtC-2r5kA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 2r5k MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
10) 		3 / 3 ASP A 237
PHE A 244
ASN A 391
 None
 0.71A 1sg9B-2r5kA:
undetectable		 1sg9B-2r5kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 2r5k MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
10) 		3 / 3 SER A 468
THR A  30
GLN A 373
 None
 0.78A 2fk8A-2r5kA:
undetectable		 2fk8A-2r5kA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2r5k MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
10) 		4 / 6 GLY A 195
GLY A  64
PHE A 366
PHE A  70
 None
 1.02A 2qx6A-2r5kA:
undetectable
2qx6B-2r5kA:
undetectable		 2qx6A-2r5kA:
18.79
2qx6B-2r5kA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 2r5k MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
10) 		4 / 4 PRO A 307
TYR A 308
GLY A 101
THR A 100
 None
 1.35A 3ib0A-2r5kA:
undetectable		 3ib0A-2r5kA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 2r5k MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
10) 		5 / 12 VAL A 330
CYH A 154
LEU A 326
VAL A 104
LEU A 368
 None
 1.19A 4po0A-2r5kA:
undetectable		 4po0A-2r5kA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2r5k MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
10) 		3 / 3 SER A 393
LEU A 379
MET A 384
 None
 0.82A 5ikrB-2r5kA:
undetectable		 5ikrB-2r5kA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 2r5k MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
10) 		3 / 3 LYS A 227
VAL A 225
ASP A 196
 None
 0.64A 6fgdA-2r5kA:
undetectable		 6fgdA-2r5kA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 2r5k MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
10) 		3 / 3 PHE A 458
ARG A 462
GLN A 457
 None
 1.06A 6g1pB-2r5kA:
undetectable		 6g1pB-2r5kA:
22.15