SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r5s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HZN_G_ACTG225_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	2r5s	UNCHARACTERIZED PROTEIN VP0806 (Vibrio parahaemolyticus)	3 / 3	PRO A 175 LEU A 176 GLN A 179	None	0.65A	3hznG-2r5sA: undetectable 3hznH-2r5sA: undetectable	3hznG-2r5sA: 25.86 3hznH-2r5sA: 25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WSJ_A_MK1A201_2 (PROTEASE)	2r5s	UNCHARACTERIZED PROTEIN VP0806 (Vibrio parahaemolyticus)	5 / 7	ARG A 276 LEU A 262 ALA A 235 VAL A 229 ILE A 261	None None None EDO A 3 (-3.6A) None	1.23A	3wsjB-2r5sA: undetectable	3wsjB-2r5sA: 22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PO0_A_NPSA602_1 (SERUM ALBUMIN)	2r5s	UNCHARACTERIZED PROTEIN VP0806 (Vibrio parahaemolyticus)	4 / 8	LYS A 154 ALA A 155 LEU A 159 LEU A 186	None	0.77A	4po0A-2r5sA: undetectable	4po0A-2r5sA: 16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZ8_A_GCSA208_1 (GLUCANASE/CHITOSANAS E)	2r5s	UNCHARACTERIZED PROTEIN VP0806 (Vibrio parahaemolyticus)	4 / 7	GLU A 206 TYR A 226 GLU A 198 ALA A 197	None None None EDO A 3 ( 4.5A)	1.13A	4zz8A-2r5sA: undetectable	4zz8A-2r5sA: 18.89

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3HZN_G_ACTG225_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","2r5s","UNCHARACTERIZED PROTEIN VP0806","Vibrio parahaemolyticus",3,"PRO A 175;LEU A 176;GLN A 179","None","0.65A","3hznG-2r5sA:undetectable;3hznH-2r5sA:undetectable","3hznG-2r5sA:25.86;3hznH-2r5sA:25.86"],["3WSJ_A_MK1A201_2","PROTEASE;PROTEASE","2r5s","UNCHARACTERIZED PROTEIN VP0806","Vibrio parahaemolyticus",5,"ARG A 276;LEU A 262;ALA A 235;VAL A 229;ILE A 261","None;None;None;EDO A   3 (-3.6A);None","1.23A","3wsjB-2r5sA:undetectable","3wsjB-2r5sA:22.09"],["4PO0_A_NPSA602_1","SERUM ALBUMIN","2r5s","UNCHARACTERIZED PROTEIN VP0806","Vibrio parahaemolyticus",4,"LYS A 154;ALA A 155;LEU A 159;LEU A 186","None","0.77A","4po0A-2r5sA:undetectable","4po0A-2r5sA:16.18"],["4ZZ8_A_GCSA208_1","GLUCANASE\/CHITOSANASE","2r5s","UNCHARACTERIZED PROTEIN VP0806","Vibrio parahaemolyticus",4,"GLU A 206;TYR A 226;GLU A 198;ALA A 197","None;None;None;EDO A   3 ( 4.5A)","1.13A","4zz8A-2r5sA:undetectable","4zz8A-2r5sA:18.89"]]