SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r5x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCT_A_ASDA1223_1 (GLUTATHIONE S-TRANSFERASE A2)	2r5x	UNCHARACTERIZED CONSERVED PROTEIN (Geobacillus kaustophilus)	4 / 8	ILE A 71 GLY A 57 ARG A 37 LEU A 74	None	0.81A	2vctA-2r5xA: undetectable	2vctA-2r5xA: 21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCT_B_ASDB1223_1 (GLUTATHIONE S-TRANSFERASE A2)	2r5x	UNCHARACTERIZED CONSERVED PROTEIN (Geobacillus kaustophilus)	4 / 8	ILE A 71 GLY A 57 ARG A 37 LEU A 74	None	0.78A	2vctB-2r5xA: undetectable	2vctB-2r5xA: 21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCT_C_ASDC1223_1 (GLUTATHIONE S-TRANSFERASE A2)	2r5x	UNCHARACTERIZED CONSERVED PROTEIN (Geobacillus kaustophilus)	4 / 8	ILE A 71 GLY A 57 ARG A 37 LEU A 74	None	0.90A	2vctC-2r5xA: undetectable	2vctC-2r5xA: 21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QYN_B_RTLB201_0 (RETINOL-BINDING PROTEIN 2)	2r5x	UNCHARACTERIZED CONSERVED PROTEIN (Geobacillus kaustophilus)	5 / 12	ILE A 71 ARG A 29 LEU A 18 LEU A 107 LEU A 8	None	1.45A	4qynB-2r5xA: undetectable	4qynB-2r5xA: 23.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2VCT_A_ASDA1223_1","GLUTATHIONE S-TRANSFERASE A2","2r5x","UNCHARACTERIZED CONSERVED PROTEIN","Geobacillus kaustophilus",4,"ILE A  71;GLY A  57;ARG A  37;LEU A  74","None","0.81A","2vctA-2r5xA:undetectable","2vctA-2r5xA:21.17"],["2VCT_B_ASDB1223_1","GLUTATHIONE S-TRANSFERASE A2","2r5x","UNCHARACTERIZED CONSERVED PROTEIN","Geobacillus kaustophilus",4,"ILE A  71;GLY A  57;ARG A  37;LEU A  74","None","0.78A","2vctB-2r5xA:undetectable","2vctB-2r5xA:21.17"],["2VCT_C_ASDC1223_1","GLUTATHIONE S-TRANSFERASE A2","2r5x","UNCHARACTERIZED CONSERVED PROTEIN","Geobacillus kaustophilus",4,"ILE A  71;GLY A  57;ARG A  37;LEU A  74","None","0.90A","2vctC-2r5xA:undetectable","2vctC-2r5xA:21.17"],["4QYN_B_RTLB201_0","RETINOL-BINDING PROTEIN 2","2r5x","UNCHARACTERIZED CONSERVED PROTEIN","Geobacillus kaustophilus",5,"ILE A  71;ARG A  29;LEU A  18;LEU A 107;LEU A   8","None","1.45A","4qynB-2r5xA:undetectable","4qynB-2r5xA:23.72"]]