SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r5y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMQ_A_BEZA3_0
(PROTEIN NDRG2)		 2r5y HOMEOTIC PROTEIN SEX
COMBS REDUCED
(Drosophila
melanogaster) 		4 / 7 TYR A 125
GLN A 150
PHE A 149
ARG A 152
 None
 1.47A 2qmqA-2r5yA:
undetectable		 2qmqA-2r5yA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 2r5y HOMEOTIC PROTEIN SEX
COMBS REDUCED
(Drosophila
melanogaster) 		3 / 3 PRO A  83
MET A  85
TYR A  82
 None
 1.04A 4qa2B-2r5yA:
undetectable		 4qa2B-2r5yA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 2r5y HOMEOTIC PROTEIN SEX
COMBS REDUCED
(Drosophila
melanogaster) 		3 / 3 TRP A 148
ARG A 152
LEU A 126
 None
 0.79A 5dbyA-2r5yA:
undetectable		 5dbyA-2r5yA:
8.41