SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r63'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 2r63 REPRESSOR PROTEIN
FROM BACTERIOPHAGE
434
(Escherichia
virus
Lambda) 		3 / 3 VAL A  54
VAL A  56
TRP A  58
 None
 0.96A 1w5uC-2r63A:
undetectable
1w5uD-2r63A:
undetectable		 1w5uC-2r63A:
19.51
1w5uD-2r63A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 2r63 REPRESSOR PROTEIN
FROM BACTERIOPHAGE
434
(Escherichia
virus
Lambda) 		3 / 3 VAL A  54
VAL A  56
TRP A  58
 None
 0.93A 3l8lC-2r63A:
undetectable
3l8lD-2r63A:
undetectable		 3l8lC-2r63A:
19.51
3l8lD-2r63A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_ACTA405_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 2r63 REPRESSOR PROTEIN
FROM BACTERIOPHAGE
434
(Escherichia
virus
Lambda) 		4 / 6 THR A  26
PRO A  42
GLN A  33
ILE A  31
 None
 1.32A 6ef6A-2r63A:
undetectable		 6ef6A-2r63A:
9.30