SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r66'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDT_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 11 TYR A 128
GLU A 184
TYR A 211
HIS A 208
GLU A 159
 F6P  A 501 (-4.6A)
None
None
None
None
 1.45A 1fdtA-2r66A:
6.0		 1fdtA-2r66A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 11 LEU A 453
GLU A 458
LYS A 193
ILE A 195
VAL A  42
 None
 1.20A 1gx9A-2r66A:
undetectable		 1gx9A-2r66A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 12 VAL A  42
SER A  43
GLY A 135
ALA A  11
VAL A  10
 None
 1.14A 1jg4A-2r66A:
undetectable		 1jg4A-2r66A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		4 / 8 THR A 448
LEU A  44
GLU A  77
TRP A 445
 None
 1.19A 1mxgA-2r66A:
undetectable		 1mxgA-2r66A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 12 TYR A 352
ILE A 265
ALA A 380
SER A 381
LEU A 373
 None
 1.06A 1nbhB-2r66A:
undetectable		 1nbhB-2r66A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		4 / 7 TYR A 352
THR A 365
GLU A 369
SER A 269
 None
 1.05A 1tv8A-2r66A:
undetectable		 1tv8A-2r66A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 12 PRO A  15
THR A 149
GLY A 129
GLY A 131
SER A 152
 None
None
None
None
F6P  A 501 (-2.9A)
 1.06A 1wg8A-2r66A:
4.1		 1wg8A-2r66A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		4 / 8 TYR A 352
THR A 365
GLU A 369
SER A 269
 None
 1.01A 2fb2A-2r66A:
undetectable		 2fb2A-2r66A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		4 / 7 TYR A 352
THR A 365
GLU A 369
SER A 269
 None
 0.93A 2fb2B-2r66A:
undetectable		 2fb2B-2r66A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_3
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 12 TYR A  75
ILE A  55
GLY A  33
LEU A  99
TYR A 128
 None
None
F6P  A 501 (-3.5A)
None
F6P  A 501 (-4.6A)
 1.41A 2nyrB-2r66A:
3.7		 2nyrB-2r66A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 12 LEU A  36
ILE A 195
ILE A 226
ARG A 450
ILE A 459
 None
 1.13A 2ygnA-2r66A:
undetectable		 2ygnA-2r66A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 11 VAL A 406
GLY A 417
ILE A 265
THR A 365
LEU A 280
 None
 1.02A 3bexC-2r66A:
2.3
3bexD-2r66A:
2.2		 3bexC-2r66A:
19.56
3bexD-2r66A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 11 THR A 365
LEU A 280
VAL A 406
GLY A 417
ILE A 265
 None
 1.04A 3bexE-2r66A:
2.5
3bexF-2r66A:
2.2		 3bexE-2r66A:
19.56
3bexF-2r66A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 11 VAL A 406
GLY A 417
ILE A 265
THR A 365
LEU A 280
 None
 1.03A 3bf1A-2r66A:
2.4
3bf1B-2r66A:
2.3		 3bf1A-2r66A:
19.56
3bf1B-2r66A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 12 THR A 365
LEU A 280
VAL A 406
GLY A 417
ILE A 265
 None
 1.03A 3bf1A-2r66A:
2.4
3bf1B-2r66A:
2.3		 3bf1A-2r66A:
19.56
3bf1B-2r66A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 11 VAL A 406
GLY A 417
ILE A 265
THR A 365
LEU A 280
 None
 1.04A 3bf1C-2r66A:
2.4
3bf1D-2r66A:
2.4		 3bf1C-2r66A:
19.56
3bf1D-2r66A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 11 THR A 365
LEU A 280
VAL A 406
GLY A 417
ILE A 265
 None
 1.05A 3bf1C-2r66A:
2.2
3bf1D-2r66A:
2.4		 3bf1C-2r66A:
19.56
3bf1D-2r66A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 11 VAL A 406
GLY A 417
ILE A 265
THR A 365
LEU A 280
 None
 1.02A 3bf1E-2r66A:
2.4
3bf1F-2r66A:
2.3		 3bf1E-2r66A:
19.56
3bf1F-2r66A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 11 THR A 365
LEU A 280
VAL A 406
GLY A 417
ILE A 265
 None
 1.04A 3bf1E-2r66A:
2.3
3bf1F-2r66A:
2.3		 3bf1E-2r66A:
19.56
3bf1F-2r66A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		4 / 8 TYR A 354
TYR A 239
SER A 360
ILE A 266
 None
 1.02A 3jz0B-2r66A:
undetectable		 3jz0B-2r66A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 12 LEU A  44
ALA A 449
VAL A  51
ILE A 456
VAL A  81
 None
 1.11A 3mwsB-2r66A:
undetectable		 3mwsB-2r66A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 12 TYR A 352
ALA A 385
GLY A 435
LEU A 397
ALA A 363
 None
 1.09A 3ou7B-2r66A:
2.9		 3ou7B-2r66A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 10 ILE A  83
PHE A  19
ILE A  56
SER A  43
HIS A 127
 None
 1.19A 3qgzA-2r66A:
undetectable		 3qgzA-2r66A:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G8Z_X_TOPX301_1
(DIHYDROFOLATE
REDUCTASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 10 ILE A 226
ALA A 449
PRO A 145
ILE A 195
TYR A  38
 None
 1.10A 4g8zX-2r66A:
undetectable		 4g8zX-2r66A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 11 GLY A 399
GLY A 400
GLY A 403
ALA A 394
LEU A 397
 None
 1.18A 4l8fB-2r66A:
2.8		 4l8fB-2r66A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		4 / 7 ASN A 112
GLU A 116
GLU A 117
GLU A  71
 None
 1.36A 4mj8C-2r66A:
undetectable		 4mj8C-2r66A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		4 / 5 TYR A 250
LYS A 246
LEU A 342
GLU A 347
 None
 1.37A 4olaA-2r66A:
3.1		 4olaA-2r66A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		4 / 8 PRO A 306
LEU A 300
VAL A 297
LEU A 271
 None
 1.00A 4pwdA-2r66A:
1.8		 4pwdA-2r66A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		4 / 7 ASN A 112
GLU A 116
GLU A 117
GLU A  71
 None
 1.31A 4r87I-2r66A:
undetectable		 4r87I-2r66A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		6 / 12 THR A 388
GLY A 372
GLY A 392
GLY A 391
ASN A 390
ALA A 374
 None
 1.31A 4uciA-2r66A:
2.2		 4uciA-2r66A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		6 / 12 THR A 388
GLY A 372
GLY A 392
GLY A 391
ASN A 390
ALA A 374
 None
 1.31A 4uciB-2r66A:
2.2		 4uciB-2r66A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		6 / 12 THR A 388
GLY A 372
GLY A 392
GLY A 391
ASN A 390
ALA A 374
 None
 1.31A 4uckA-2r66A:
2.1		 4uckA-2r66A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 12 GLY A 129
GLY A 150
LEU A  13
GLY A 131
GLY A 132
 None
 1.10A 4yvgA-2r66A:
undetectable		 4yvgA-2r66A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		4 / 6 TYR A 250
LYS A 246
LEU A 342
GLU A 347
 None
 1.32A 4z4cA-2r66A:
4.6		 4z4cA-2r66A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		4 / 5 TYR A 250
LYS A 246
LEU A 342
GLU A 347
 None
 1.23A 4z4hA-2r66A:
2.8		 4z4hA-2r66A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 8 ALA A 349
VAL A 234
GLY A 350
ALA A 353
GLY A 237
 None
 1.44A 4zjzB-2r66A:
undetectable		 4zjzB-2r66A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 11 ALA A 421
VAL A 404
LEU A 418
LEU A 280
VAL A 406
 None
 1.31A 5eb5A-2r66A:
1.8		 5eb5A-2r66A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		4 / 5 TYR A 250
LYS A 246
LEU A 342
GLU A 347
 None
 1.41A 5js1A-2r66A:
3.1		 5js1A-2r66A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		3 / 3 VAL A 361
SER A 360
TRP A 428
 None
 0.99A 5jwaA-2r66A:
3.5		 5jwaA-2r66A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		4 / 5 ARG A 442
PHE A 371
LEU A 373
LEU A 397
 None
 1.36A 5veuH-2r66A:
undetectable		 5veuH-2r66A:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		4 / 8 ILE A 194
TYR A  38
VAL A 225
ASP A 221
 None
 1.16A 5vlmF-2r66A:
undetectable		 5vlmF-2r66A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11802_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
UL4
RIBOSOMAL PROTEIN
UL15
RIBOSOMAL PROTEIN
EL15)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		3 / 3 ARG A 301
LYS A 246
ARG A 270
 None
 1.25A 6az3C-2r66A:
undetectable
6az3L-2r66A:
undetectable
6az3M-2r66A:
undetectable		 6az3C-2r66A:
9.45
6az3L-2r66A:
9.22
6az3M-2r66A:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		3 / 3 TYR A 354
ALA A 264
LEU A 251
 None
 0.62A 6d9kF-2r66A:
2.5		 6d9kF-2r66A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_2
(-)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		5 / 9 THR A 187
GLY A 132
GLY A 131
HIS A 127
VAL A  39
 None
 1.48A 6gnfA-2r66A:
9.8		 6gnfA-2r66A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 2r66 GLYCOSYL
TRANSFERASE, GROUP 1
(Halothermothrix
orenii) 		4 / 6 PRO A 384
TRP A 428
GLY A 435
GLU A 433
 None
 1.09A 6gqiA-2r66A:
undetectable		 6gqiA-2r66A:
21.07