SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r6i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 2r6i UNCHARACTERIZED
PROTEIN ATU1473
(Agrobacterium
fabrum) 		3 / 3 ALA A 155
VAL A 152
TRP A 148
 None
 0.89A 1jnoA-2r6iA:
undetectable		 1jnoA-2r6iA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 2r6i UNCHARACTERIZED
PROTEIN ATU1473
(Agrobacterium
fabrum) 		3 / 3 ALA A 155
VAL A 152
TRP A 148
 None
 0.88A 1jnoB-2r6iA:
undetectable		 1jnoB-2r6iA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 2r6i UNCHARACTERIZED
PROTEIN ATU1473
(Agrobacterium
fabrum) 		6 / 11 ALA A 207
ILE A 115
VAL A 145
LEU A 254
THR A 194
ALA A 191
 None
 1.32A 1rv7A-2r6iA:
undetectable
1rv7B-2r6iA:
undetectable		 1rv7A-2r6iA:
15.98
1rv7B-2r6iA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 2r6i UNCHARACTERIZED
PROTEIN ATU1473
(Agrobacterium
fabrum) 		4 / 4 LEU A 189
ARG A 117
LEU A 116
ALA A 110
 None
 1.15A 3b9mA-2r6iA:
undetectable		 3b9mA-2r6iA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2r6i UNCHARACTERIZED
PROTEIN ATU1473
(Agrobacterium
fabrum) 		4 / 4 LEU A   8
PRO A  28
LEU A   5
ARG A  95
 None
 1.28A 3hcoB-2r6iA:
undetectable		 3hcoB-2r6iA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 2r6i UNCHARACTERIZED
PROTEIN ATU1473
(Agrobacterium
fabrum) 		4 / 8 ALA A 253
VAL A 256
LEU A 260
LEU A 189
 None
 0.64A 3roxA-2r6iA:
undetectable		 3roxA-2r6iA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 2r6i UNCHARACTERIZED
PROTEIN ATU1473
(Agrobacterium
fabrum) 		5 / 7 VAL A  97
LEU A  64
ALA A 100
LEU A  71
LEU A 260
 None
 1.09A 5jq7A-2r6iA:
undetectable		 5jq7A-2r6iA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 2r6i UNCHARACTERIZED
PROTEIN ATU1473
(Agrobacterium
fabrum) 		5 / 12 ALA A 207
LEU A 204
ALA A 205
TYR A 183
LEU A 180
 None
 1.15A 5k9dA-2r6iA:
undetectable		 5k9dA-2r6iA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 2r6i UNCHARACTERIZED
PROTEIN ATU1473
(Agrobacterium
fabrum) 		4 / 7 GLN A 232
ASP A 227
ALA A 220
LEU A 221
 None
 1.07A 5nwvA-2r6iA:
undetectable		 5nwvA-2r6iA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2r6i UNCHARACTERIZED
PROTEIN ATU1473
(Agrobacterium
fabrum) 		4 / 5 LEU A 180
LYS A 182
LEU A 206
GLU A 210
 None
 1.33A 5weaA-2r6iA:
undetectable		 5weaA-2r6iA:
15.95