SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r73'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 2r73 TRICHOSURIN
(Trichosurus
vulpecula) 		4 / 7 LEU A  61
ALA A  80
PHE A  89
VAL A  99
 None
 0.85A 1epbA-2r73A:
15.0		 1epbA-2r73A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 2r73 TRICHOSURIN
(Trichosurus
vulpecula) 		3 / 3 PHE A 129
PHE A 112
PHE A 114
 None
 0.70A 2od9A-2r73A:
undetectable		 2od9A-2r73A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 2r73 TRICHOSURIN
(Trichosurus
vulpecula) 		3 / 3 PHE A 129
PHE A 112
PHE A 114
 None
 0.70A 2qqgA-2r73A:
undetectable		 2qqgA-2r73A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 2r73 TRICHOSURIN
(Trichosurus
vulpecula) 		3 / 3 PHE A 112
ASN A 127
PHE A 114
 None
 1.08A 2zbuD-2r73A:
undetectable		 2zbuD-2r73A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 2r73 TRICHOSURIN
(Trichosurus
vulpecula) 		4 / 5 SER A  35
VAL A 125
ASN A 127
PRO A  46
 None
 1.38A 6fi4A-2r73A:
undetectable
6fi4B-2r73A:
undetectable		 6fi4A-2r73A:
22.55
6fi4B-2r73A:
9.43